An interventional study of Sample collection in Methicillin-Resistant Staphylococcus Aureus Colonization, sponsored by Centre Hospitalier de Saint-Brieuc. Not yet recruiting at 2 sites in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-06.
Sponsored by Centre Hospitalier de Saint-Brieuc · Not applicable, Interventional, and Basic science
Antimicrobial resistance is a major public health issue. Methicillin resistance in Staphylococcus aureus (MRSA) is one of the indicators that is monitored particularly closely. In animals, pig farms, among others, have been identified as reservoirs of MRSA, with a risk of transmission to humans, particularly to individuals in direct contact with livestock. In France, the prevalence of MRSA in pig farms has increased markedly in recent years.
While cross-species transmission between pigs and humans in professional settings is well-documented, the temporal dynamics, the actual incidence of acquisition, and the associated determinants remain insufficiently characterized in France.
Adopting a "One Health" approach, this project aims to gain a better understanding of the mechanisms by which MRSA spreads between animal and human subpopulations and to incorporate these insights into a mathematical modeling framework.
The participants in this project will be farmers representing 20 different pig farms, the majority of which will be located in Brittany-a region recognized as the leading pork-producing area in France.
Participants will be asked to provide two types of samples, only one of which will contain personally identifiable data.
These successive samplings will be carried out over time in order to analyze carriage dynamics and estimate epidemiological parameters of interest. A modeling component will be incorporated to make use of the data collected.
303 studies on the registry are indexed under Staphylococcal Infections; 34 are open to participants now.
This study's planned enrollment of 20 is below the median of 124 across 198 interventional studies indexed under Staphylococcal Infections.
Browse Staphylococcal Infections studies →Centre Hospitalier de Saint-Brieuc is the lead sponsor of 9 studies on the registry; 3 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Other: Sample collection
Participants will be asked to provide two types of samples, only one of which will contain personally identifiable information. * Nasal samples: a monthly self-collected nasal swab, performed at approximately the same time each month. * Dust samples: following the collection and storage of the nasal swab, participants will be asked to collect dust samples from the production area-specifically, from the room within the fattening facility that houses the oldest animals-by wiping surfaces using a small cloth.
To estimate the prevalence of nasal carriage of MRSA among pig farmers during the study period.
The primary outcome measure is the prevalence of nasal carriage of MRSA among pig farmers during the study period, as determined by microbiological detection from self-collected nasal swabs.
Time frame: From enrollment to the end of the study : 24 months
Describe the temporal dynamics of nasal carriage of Staphylococcus aureus among pig farmers and within farms.
The prevalence of nasal carriage of MSSA among pig farmers.
Time frame: From enrollment to the end of the study : 24 months
Estimate the incidence of acquisition and clearance of MRSA and MSSA among pig farmers and within farms, based on repeated longitudinal measurements.
The incidence of acquisition and clearance of MRSA and MSSA among pig farmers, estimated from repeated longitudinal measurements of nasal carriage.
Time frame: From enrollment to the end of the study : 24 months
Identify factors associated with the carriage and acquisition of MRSA among pig farmers.
The prevalence and incidence of MSSA and MRSA within the pig farm environment.
Time frame: From enrollment to the end of the study : 24 months
Plan to share: Undecided
No publications or documents are linked to this record.
Start is estimated for Nov 2026; primary completion for Nov 2028, 24 months later.
Of 30 non-industry interventional studies with no phase under Staphylococcal Infections, half reached primary completion within 21 months of starting (the median), counting those still running; a quarter within 14 and three quarters within 57. This study's planned 24 months is above that.
Counting every sponsor, half of 32 studies reached it within 21 months; a quarter within 14 and three quarters within 57.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier de Saint-Brieuc