An interventional study of Rehabilitation in ICU-acquired Weakness, sponsored by Asan Medical Center. Not yet recruiting at 1 site in South Korea. Open to participants aged 18 Years to 79 Years. Per ClinicalTrials.gov, last updated 2026-10-26.
Sponsored by Asan Medical Center · Not applicable, Interventional, and Treatment
This pilot study aims to evaluate the efficacy, safety, feasibility, and user satisfaction of "Rehabit: swim," a customized, evidence-based, motion-recognition-based rehabilitation exergame designed for hospitalized patients with limited mobility, particularly those with a history of intensive care unit (ICU) admission. A total of 20 participants will perform the rehabilitation exergaming program while lying or sitting in bed. The intervention consists of 30-minute sessions, once a day, for a total of 10 sessions over approximately 2 weeks. Clinical outcomes, physical performance measures, and user experience metrics will be assessed before and after the intervention.
Background \& Rationale: Hospitalized patients, especially those recovering from critical illnesses or experiencing ICU-acquired weakness (ICU-AW) and sarcopenia, often face severe mobility restrictions. While early rehabilitation is crucial for functional recovery and reducing complications, available exercise options for bedridden patients are frequently monotonous, limiting patient motivation and adherence. To overcome these limitations, "Rehabit: swim," a customized interactive exergame optimized for bedridden patients, was developed.
Study Objectives: The primary objective is to investigate the efficacy, safety, and feasibility of utilizing the Rehabit: swim exergaming program in improving physical function, muscle strength, mobility, and quality of life among hospitalized patients with a history of ICU stays.
Study Design \& Methods:
Design: A prospective, single-center pilot study. Participants: 20 adult inpatients (≥19 years old) who meet the inclusion and exclusion criteria, including a history of ICU admission during their hospital stay.
Intervention: Participants will perform tailored rehabilitation exercise games using Rehabit: swim while in a bed (lying or sitting posture). The intervention is planned for 30 minutes per session, once daily, 10 sessions total within a 2-week period (extendable up to 3 weeks depending on condition).
Outcomes and Data Collection:
Clinical \& Functional Assessments: Evaluated at pre- and post-intervention, including Medical Research Council Sum Score (MRC-SS), grip strength, Functional Ambulatory Category (FAC), ICU Mobility Scale (ICU-MS), EQ-5D, EQ-VAS, K-MMSE2, Intrinsic Motivation Inventory (IMI), and Game User Experience Satisfaction Scale-18 (GUESS-18).
Intervention Metrics: Physical motion data (range of motion, angles, speed) captured via Inertial Measurement Units (IMUs), built-in metrics (calories burned, game scores, exercise time), heart rate changes, adherence, session completion/cessation reasons, and adverse events (e.g., falls).
Asan Medical Center is the lead sponsor of 578 studies on the registry; 74 are open to participants now.
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Exclusion Criteria:
All participants will receive the Rehabit: swim rehabilitation exergaming intervention for approximately 2 weeks (total of 10 sessions, 30 minutes per session) while in a bed (lying or sitting posture).
Device: Rehabilitation
Hospitalized patients with limited mobility, including those with a history of intensive care unit (ICU) admission, will perform customized rehabilitation exercise games using the "Rehabit: swim" motion-recognition system in a bed setting. The intervention is administered for 30 minutes per session, once daily, totaling 10 sessions over approximately 2 weeks.
Session Adherence Rate
Percentage of the 10 planned Rehabit: swim sessions attended by each participant, calculated as (number of sessions attended ÷ 10) × 100. A session is counted as attended when the participant starts the scheduled exercise-game session.
Time frame: From the first intervention session (Game 1) through the tenth session (Game 10), up to 3 weeks
Intervention Completion Rate
Percentage of enrolled participants who complete all 10 Rehabit: swim sessions within 3 weeks of the first session.
Time frame: From the first intervention session (Game 1) through the tenth session (Game 10), up to 3 weeks
Medical Research Council Sum Score (MRC-SS)
Change in muscle strength assessed using the MRC-SS. Scores range from 0 to 60; higher scores indicate greater muscle strength (better outcome).
Time frame: Baseline and post-intervention (approx. 2 weeks).
Grip Strength
Change in handgrip strength.
Time frame: Baseline and post-intervention (approx. 2 weeks).
Functional Ambulatory Category (FAC)
Changes in functional mobility and ambulation status measured by the Functional Ambulation Category (FAC). Scores range from 0 (nonfunctional ambulator) to 5 (independent ambulator on any surface, including stairs); higher scores indicate greater walking independence (better outcome).
Time frame: Baseline and post-intervention (approx. 2 weeks).
ICU Mobility Scale (ICU-MS)
Changes in functional mobility and ambulation status measured by the Intensive Care Unit Mobility Scale (ICU-MS). Scores range from 0 (lying in bed, no active movement) to 10 (walking independently without a gait aid); higher scores indicate greater mobility (better outcome).
Time frame: Baseline and post-intervention (approx. 2 weeks).
EQ-5D-5L Index
Health-related quality of life measured with the EuroQol 5-Dimension 5-Level questionnaire (EQ-5D-5L), which assesses mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, each rated on 5 levels from no problems to extreme problems. Responses are converted to a single index value using the Korean EQ-5D-5L value set (range -0.066 to 1; higher values indicate better health). Change is calculated as the post-intervention value minus the baseline value; positive values indicate improvement.
Time frame: Baseline and post-intervention (approx. 2 weeks).
EQ-VAS
Self-rated overall health measured with the EQ-VAS, ranging from 0 (worst imaginable health) to 100 (best imaginable health); higher scores indicate better self-rated health. Change is calculated as the post-intervention score minus the baseline score; positive values indicate improvement.
Time frame: Baseline and post-intervention (approx. 2 weeks).
Intrinsic Motivation Inventory (IMI) Interest/Enjoyment Subscale Score
Intrinsic motivation toward the Rehabit: swim exercise game measured with the Interest/Enjoyment subscale of the IMI, consisting of 7 items rated from 1 ("not at all true") to 7 ("very true"), with 2 items reverse-scored. The subscale score is the mean of the 7 items (range 1 to 7); higher scores indicate greater intrinsic motivation.
Time frame: Baseline and post-intervention (approx. 2 weeks).
Game User Experience Satisfaction Scale-18 (GUESS-18) Composite Score
Satisfaction with the Rehabit: swim exercise game measured with the GUESS-18, consisting of 18 items across 9 subscales rated from 1 ("strongly disagree") to 7 ("strongly agree"), with 1 item reverse-scored. Items are averaged within each subscale, and the 9 subscale scores are summed to obtain the composite score (range 9 to 63); higher scores indicate greater game satisfaction.
Time frame: Baseline and post-intervention (approx. 2 weeks).
Plan to share: No
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Start is estimated for Nov 2026; primary completion for Sep 2027, 10 months later.
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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