A Phase 4 interventional study of Amoxicillin 2g and Clindamycin 600 mg in Wisdom Tooth Removal, Antibiotic Prophylaxis and Single Dose, sponsored by Dow University of Health Sciences. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-26.
Sponsored by Dow University of Health Sciences · Phase 4, Interventional, and Prevention
The goal of this clinical trial is to learn which drug amongst Amoxicillin, Clindamycin and Azithromycin single dose works better in reducing post-surgical complications in Participants getting lower wisdom teeth pulled. The main question it aims to answer is:
Participants will:
In this Clinical Trial, Principal Investigator is comparing three single dose antibiotic drugs by comparing post-operative outcomes of Lower third molar extraction (Wisdom Tooth getting pulled).
After checking for Participant's eligibility. Participants will be asked for their consent to be part of research and then Initial Baseline reading will be measured and then they will be given medication and will be asked to take it and wait for an hour.
After Surgery, once participant is calmed down Investigators will wait for 25-30mins and will record 2nd set of readings to check the effect of surgery on pain, mouth opening, bleeding.
After Surgery day 3 participant will be called for follow-up that's when third set of readings will be measured.
Post Data Collection Data Analysis will be done using SPSS 21
Dow University of Health Sciences is the lead sponsor of 176 studies on the registry; 32 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
This Group will receive Amoxicillin Single dose
Drug: Amoxicillin 2g
This Group will receive Clindamycin Single dose
Drug: Clindamycin 600 mg
This group will receive Azithromycin Single dose
Drug: Azithromycin 500mg
single dose
Single dose
Single dose
No. of Participants with Dry Socket
Alveolar Osteitis, sharp pain accompanied by smell and absence of blood clot. Reported as yes or no
Time frame: from baseline pre-surgery to third day post-surgery
No. of Participants with Surgical Site Infection
Surgical Site infection presence of post-operative granulation tissue or non-healing, reported as yes or no
Time frame: from baseline pre-surgery to third day post-surgery
No. of Participants with Trismus
Inability to open jaw till normal mouth opening range
Time frame: from baseline pre-surgery to third day post-surgery
Mean and Standard Deviation of Pain Score
Pain Score measured on Likert scale. Where low score means less pain and higher score means more pain.
Time frame: from baseline pre-surgery to third day post-surgery
No. of Participants with Bleeding
Presence and absence of Bleeding
Time frame: from baseline pre-surgery to third day post-surgery
No study locations are listed for this record.
Documents are hosted by the registry — open the source record to download them.
Plan to share: Yes — IPD that's used for results publication
Supporting information: Study protocol, Informed consent form
Time frame: December 2026- December 2027
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Clindamycin
Dow University of Health Sciences →