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RecruitingNCT07892820Updated Oct 23, 2026

Evaluation of Different Grafting Technique of Thin Gingival Phenotype With Delayed Dental Implants

An interventional study of De-epithelized connective tissue graft and Sub-epithelized connective tissue graft in Implant Dentistry and Connective Tissue Graft, sponsored by Future University in Egypt. Recruiting at 1 site in Egypt. Open to participants aged 20 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-10-23.

Sponsored by Future University in Egypt · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 8 months after the study started (first participant enrolled Jan 2025, registered Oct 2026).
  • Started Jan 2025; still recruiting 1 year 8 months later.
Updated Oct 23, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
24
Allocation
Randomized
Ages
20 Years to 50 Years
Sex
All
01

Study summary

Implant dentistry has become a fundamental aspect of modern dental practice, with its success now determined by more than just Osseo integration. Various factors play a critical role in the long-term success of dental implants, one of the most important being the stability of the peri-implant soft tissues, which are essential for maintaining both function and aesthetics. This study aims to compare the outcomes of sub epithelial connective tissue grafts and de-epithelialized connective tissue grafts in conjunction with delayed implant placement.

02

Conditions studied

  • Implant Dentistry
  • Connective Tissue Graft
03

In context

Lead sponsor

Future University in Egypt is the lead sponsor of 103 studies on the registry; 30 are open to participants now.

Browse Future University in Egypt studies →

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Thin gingival phenotype \< 1.5mm.[6]
  • Medical free.
  • Single edentulous area.
  • Age range is between 20 to 50 years.
  • Gingival recession.
  • Free from any periodontal disease.
  • Positive patient's acceptance for participating in the study.
  • Patients able to sign informed consent.
  • Non-smokers.
  • Moderate palatal vault.
  • Thickness of palatal graft not \<2mm.
  • Width of bone not \<8mm.

Exclusion criteria

Exclusion Criteria:

  • Psychologically disturbed patients.
  • Patients with a history of allergy to any medication used in the study were excluded.
  • Osteoporosis.
  • Parafunctional habit.
  • Patients taking anticoa
  • Gulant therapy.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
24 participants (estimated)

Study arms

  • Experimental
    De-epithelized connective tissue graft with thin gingival phenotype with delayed implant placement.

    Procedure: De-epithelized connective tissue graft

  • Active comparator
    Sub-epithelized connective tissue graft

    Procedure: Sub-epithelized connective tissue graft

Interventions

  • ProcedureDe-epithelized connective tissue graft

    A free gingival graft will be harvested, de-epithelialized extra-orally, producing a 1.5 mm thick connective tissue graft. The graft will be inserted into the buccal pouch and will be sutured with resorbable sutures. Gel foam will be placed in the donor site and sutured, with a stent fixed in place.

  • ProcedureSub-epithelized connective tissue graft

    A free gingival graft will be harvested,and sub-epithelized intra-orally, producing a 1.5 mm thick connective tissue graft. The graft will be inserted into the buccal pouch and will be sutured with resorbable sutures. Gel foam will be placed in the donor site and sutured, with a stent fixed in place.

06

What researchers measure

Primary outcomes

  1. Gingival index

    Soft tissue healing clinical examination

    Time frame: baseline, after 6 months

Secondary outcomes

  1. Bone Density

    Radiographic examination

    Time frame: baseline, after 6 months

07

Study locations

1 of 1 sites recruiting
  • Future University in Egypt
    Cairo, Egypt
    Recruiting
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jan 2025 (actual). Primary completion is estimated for Dec 2026, 23 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 18, 2026
First posted
Oct 23, 2026
StartActual
Jan 30, 2025
Primary completionEst.
Dec 31, 2026
CompletionEst.
Jan 30, 2027
Last update
Oct 23, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 23, 2026
Show all 1 update
  1. Oct 23, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07892820
Lead sponsor
Future University in Egypt
Responsible party
Hossam Rushdy Al Araby (Master Degree Candidate in Periodontology Department -Faculty of Oral and Dental Medicine - Future university in Egypt, Future University in Egypt) — Principal investigator
First posted
Oct 23, 2026
Start date
Jan 30, 2025
Primary completion
Dec 31, 2026 (estimated)
Completion
Jan 30, 2027 (estimated)
Last update
Oct 23, 2026

Study contacts

Hossam Rushdy Master Candidate, Bachelor Degree
Contact
Hosam.Roshdy.1996@hotmail.com
+20 11 55436000

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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