An interventional study of Biomechanical motion analysis in Chronic Lateral Ankle Instability, sponsored by Clinique du Sport, Bordeaux Mérignac. Recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-21.
Sponsored by Clinique du Sport, Bordeaux Mérignac · Not applicable, Interventional, and Treatment
Chronic lateral ankle instability is a common condition in athletic populations and may lead to persistent biomechanical alterations despite appropriate management. This condition typically develops following one or more ankle sprains and is characterized by a sensation of instability, episodes of the ankle giving way, pain, or discomfort during physical or sporting activities. When conventional treatments such as rehabilitation, physiotherapy, and activity modification do not provide sufficient improvement, surgical ligament repair may be recommended.
Although this surgery generally restores ankle stability, there is currently limited evidence regarding how lower-limb function evolves following the procedure. In particular, there is no established objective reference measure to assess functional recovery and support healthcare professionals in making decisions regarding rehabilitation or return to sport.
The prospective interventional comparative analysis proposed in this study aims to evaluate surgery-induced changes in ankle and lower-limb movement and function that can be objectively quantified through biomechanical motion analysis.
Clinique du Sport, Bordeaux Mérignac is the lead sponsor of 11 studies on the registry; 11 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Relapsed: the illness came back after treatment had worked. Refractory: it did not respond to treatment, or stopped responding while still on it.
Relapsed and refractory
Relapsed: the illness came back after treatment had worked. Refractory: it did not respond to treatment, or stopped responding while still on it.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants with chronic lateral ankle instability who regularly engage in physical activity and/or sports and are scheduled to undergo lateral ankle ligament repair. Biomechanical motion analysis will be performed preoperatively and at 3 and 6 months postoperatively.
Other: Biomechanical motion analysis
The studied parameters will be categorized as follows: Kinematics * Ankle dorsiflexion/plantarflexion, inversion/eversion, and foot internal/external rotation angles * Knee flexion and valgus/varus angles * Hip flexion, adduction/abduction, and internal/external rotation angles * Trunk flexion/extension * Pelvic frontal plane tilt Kinetics and Inverse Dynamics * Ankle, knee, and hip extensor joint moments * Knee adduction moment * Positive and negative joint power at the knee and ankle * Vertical ground reaction force (vGRF) * Anterior-posterior braking and propulsion forces Spatiotemporal Parameters * Ground contact time * Stance and flight phase durations * Jump height (countermovement jump \[CMJ\] and drop jump) The three-dimensional biomechanical analysis will be performed using a 12-camera Qualisys MIQUS M3 motion capture system synchronized with two floor-embedded AMTI force platforms to quantify lower-limb kinematics, kinetics, and spatiotemporal parameters
Also known as: three-dimensional biomedical motion analysis, Functional biomechanical analysis
Change in biomechanical parameters derived from three-dimensional motion analysis
Change in Kinematic parameters derived from three-dimensional motion analysis between the preoperative assessment (T0), the 3-month postoperative assessment (T1), and the 6-month postoperative assessment (T2). Kinematic variables include ankle, knee, hip, trunk, and pelvic joint angles (°). Data will be collected using a 12-camera Qualisys MIQUS M3 optoelectronic motion capture system (Qualisys AB, Gothenburg, Sweden).
Time frame: From enrollement to 6 months after surgery
Changes in Kinetic Moments Measurements
Kinetic and inverse dynamics measures at T0, T1, and T2 include : * Ankle, knee, and hip extensor joint moments (N·m/kg) * Knee adduction moment (N·m/kg)
Time frame: From enrollement to 6 months after surgery
Changes in Spatiotemporal Parameters
Spatiotemporal parameters measured at T0, T1, and T2 include: * Ground contact time (s) * Stance phase duration (s) * Flight phase duration (s)
Time frame: From enrollement to 6 months after surgery
Limb Symmetry Index (LSI) for selected biomechanical parameters
Inter-limb symmetry will be expressed as a Limb Symmetry Index (LSI), calculated as: LSI = (Operated limb value / Contralateral limb value) × 100 Values will be expressed as percentages (%). Separate analyses will be performed for each predefined biomechanical parameter.
Time frame: From enrollement to 6 months after surgery
Change in Limb Symmetry Index over time
Evolution of the Limb Symmetry Index (LSI) between baseline (T0), 3 months (T1), and 6 months (T2) following surgery.
Time frame: From inclusion to 6 months post-surgery
Countermovement Jump (CMJ) Height
Vertical jump height measured during the Countermovement Jump (CMJ), expressed in centimeters.
Time frame: From Inclusion to 6 months post-surgery
Drop Jump Height
Vertical jump height measured during the Drop Jump task, expressed in centimeters.
Time frame: From enrollement to 6 months after surgery
Changes in Kinetic Joint Power Measurements
Kinetic and inverse dynamics measures at T0, T1, and T2 include : Positive and negative joint power at the knee and ankle (W/kg)
Time frame: From enrollement to 6 months after surgery
Changes in Kinetic Vertical ground reaction force Measurements
Kinetic and inverse dynamics measures at T0, T1, and T2 include : Vertical ground reaction force (vGRF) (N)
Time frame: From enrollement to 6 months after surgery
Changes in Kinetic Reaction Forces Measurements
Kinetic and inverse dynamics measures at T0, T1, and T2 include : Anterior-posterior braking and propulsive ground reaction forces (N/kg)
Time frame: From enrollement to 6 months after surgery
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Oct 2026; primary completion for Jun 2028, 20 months later.
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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Clinique du Sport, Bordeaux Mérignac