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Not yet recruitingNCT07884032Updated Oct 20, 2026

Expression Intensity Modulates Social Intention Understanding in ASD Children

An observational study in Autism Spectrum Disorder (ASD), sponsored by University of Electronic Science and Technology of China. Not yet recruiting. Open to participants aged 5 Years to 8 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-20.

Sponsored by University of Electronic Science and Technology of China · Observational

Updated Oct 20, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
90
Ages
5 Years to 8 Years
Sex
All
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Study summary

Children watch videos of a single model playing with toys, judge whether the model desires a new toy based on observing the model's varying expression intensities, and form a judgment on whether the model intends to obtain a new toy or not. During this process, children's eye-tracking data are recorded, and changes in blood oxygen levels in the cerebral cortex are captured via functional near-infrared spectroscopy (fNIRS) equipment. This study discusses children's social attention and the corresponding neural mechanisms during the intention understanding process.

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Conditions studied

  • Autism Spectrum Disorder (ASD)

Keywords

  • Intention understanding
  • Expression intensity
  • eye-tracking
  • functional near-infrared spectroscopy
  • social cognition
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In context

Autism Spectrum Disorder

1,755 studies on the registry are indexed under Autism Spectrum Disorder; 507 are open to participants now.

This study's planned enrollment of 90 is below the median of 102 across 328 observational studies indexed under Autism Spectrum Disorder.

Browse Autism Spectrum Disorder studies →

Lead sponsor

University of Electronic Science and Technology of China is the lead sponsor of 112 studies on the registry; 37 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
5 Years to 8 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

An estimated 90 Chinese children participated in this study, with 30 in the TD group, 30 in the ASD group, and 30 in the ID group. Children with ASD and ID were recruited from private or public specialist schools in Chengdu, while TD children were from primary school and kindergarten in Shehong City, Sichuan Province. The average age was 7 years old, including 15 males and 15 females in each group. Eye-tracking data with a sampling rate below 70% will be excluded from analysis.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • For the TD group: Typically developing children without any developmental or neurological disorders.
  • For the ASD group: Confirmed clinical diagnosis of Autism Spectrum Disorder (ASD) and reconfirmed by the criteria of the Diagnostic Observation Table for ASD, Second Edition (ADOS-2).
  • For the ID group: Confirmed clinical diagnosis of Intellectual Disability (ID) and the ADOS-2 with a comparison score below the ASD diagnostic cut-off score (comparison score ≤ 2).
  • All groups: Normal or corrected-to-normal vision, no color vision deficiencies.
  • All groups: Legal guardian provided written informed consent.

Exclusion criteria

Exclusion Criteria:

  • Failure to meet the study's group-specific screen cutoffs on the Social Responsiveness Scale (SRS) and ADOS-2.
  • Known genetic syndromes.
  • Significant hearing loss.
  • Uncorrectable visual impairment.
05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
90 participants (estimated)
Patient registry
No

Groups and cohorts

  • Typically Developing Children (TD)group
  • Autism Spectrum Disorder (ASD) Group
  • Intellectual Disability(ID) Group
06

What researchers measure

Primary outcomes

  1. The proportions of fixation duration

    The fixation duration proportion for each area of interest (AOI) was calculated as the ratio of the fixation duration of different AOIs (face, hand) to the total fixation duration of the screen.

    Time frame: During the first 13 seconds video presentation.

  2. The proportion of fixation duration on the screen displaying correct answers

    The ratio of gaze duration on the correct answer screen to total gaze duration during the stage when judging whether the model wanted or did not want the new toy.

    Time frame: Experimental material video from 18 seconds to 26 seconds

  3. Changes in cerebral cortex blood oxygen concentration

    Changes in blood oxygen concentration in the cerebral cortex were monitored throughout the entire experimental procedure.

    Time frame: Each trial lasts 26 seconds, followed by a 20-second rest interval, for a total of 18 trials.

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Oct 2026; primary completion for Dec 2026, 2 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 8, 2026
First posted
Oct 20, 2026
StartEst.
Oct 10, 2026
Primary completionEst.
Dec 10, 2026
CompletionEst.
Dec 31, 2026
Last update
Oct 20, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 20, 2026
Show all 1 update
  1. Oct 20, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07884032
Responsible party
Shan Gao (Professor, University of Electronic Science and Technology of China) — Principal investigator
First posted
Oct 20, 2026
Start date
Oct 10, 2026 (estimated)
Primary completion
Dec 10, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Oct 20, 2026

Study contacts

Shan Gao
Contact
hohxil@sina.com
86+13541290631
Shan Gao, Dr
principal investigator · School of Foreign Languages, University of Electronic Science and Technology of China, Chengdu

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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