An interventional study of Medial-Support Knee Brace and Eccentric Loading Exercise in Pes Anserine Bursitis, sponsored by Dr Aneeqa Sultan. Completed at 2 sites in Pakistan. Open to participants aged 20 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-10-20.
Sponsored by Dr Aneeqa Sultan · Not applicable, Interventional, and Treatment
This study aims to compare the effects of knee bracing and eccentric loading exercises on pain and functional ability in adults with acute pes anserine bursitis. Pes anserine bursitis is a condition affecting the inner side of the knee that can cause pain and difficulty with activities such as walking, climbing stairs, and standing up from a chair.
A total of 32 participants will be included in the study and divided into two groups. One group will receive a knee-bracing intervention, while the other group will participate in a structured exercise program involving eccentric loading and strengthening exercises for the muscles around the knee.
The bracing group will be instructed to wear a properly fitted medial-support knee brace for approximately 6-8 hours daily during weight-bearing activities. The exercise group will perform prescribed exercises three times per week for eight weeks, with exercise intensity adjusted according to individual tolerance.
Pain intensity and knee-related functional ability will be assessed using the Visual Analogue Scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Assessments will be conducted before treatment and at the planned follow-up visits to evaluate changes in symptoms and function.
The findings are intended to help determine which intervention provides greater improvement in pain and functional ability in people with acute pes anserine bursitis and may help guide physiotherapy treatment decisions.
Pes anserine bursitis is a condition involving irritation or inflammation of the bursa located near the insertion of the sartorius, gracilis, and semitendinosus tendons on the inner side of the knee. It may cause localized pain and tenderness and can limit daily activities, including walking, climbing stairs, standing up from a chair, and performing other movements involving the knee.
Conservative physiotherapy management may include exercise therapy and external support. Exercise therapy aims to improve the strength and functional capacity of the muscles surrounding the knee, while a knee brace may provide support during weight-bearing activities. However, further comparative evidence is needed to determine which approach provides greater improvements in pain and functional ability in patients with acute pes anserine bursitis.
**Study objective**
The objective of this randomized controlled trial is to compare the effects of knee bracing and eccentric loading exercises on pain intensity and knee-related functional ability in adults with acute pes anserine bursitis. The study is intended to determine whether either intervention provides greater improvement in the measured outcomes.
**Study design and treatment groups**
The study uses a two-group, parallel randomized controlled trial design. Eligible participants are assigned to one of two intervention groups following screening and informed consent. The planned sample comprises 32 participants, with 16 participants allocated to each group.
**Bracing group**
Participants assigned to the bracing group receive a properly fitted medial-support knee brace. The prescribed wearing schedule is approximately 6-8 hours daily during weight-bearing activities for eight weeks. Participants are instructed on the correct use and care of the brace.
**Eccentric loading exercise group**
Participants assigned to the exercise group follow a structured exercise program targeting the muscles surrounding the knee, including the quadriceps and hamstrings. The program includes strengthening and functional exercises, such as leg raises, hamstring curls, and step-ups. Exercises are prescribed three times per week for eight weeks, with three sets of approximately 10-15 repetitions, adjusted according to the participant's tolerance and ability. Exercise intensity progresses gradually as tolerated.
**Outcome assessment**
Pain intensity is assessed using the Visual Analogue Scale (VAS), and knee-related symptoms and functional limitations are assessed using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). These instruments are used to evaluate changes in pain and function over the course of the intervention.
Baseline assessments are performed before treatment. Follow-up assessments are planned to evaluate treatment response and determine whether improvements are maintained. The final assessment schedule should correspond to the actual visits completed and the time points specified in the approved study protocol.
**Data analysis**
Participant characteristics are summarized using descriptive statistics. Within-group changes and between-group differences in pain and functional outcomes are evaluated using appropriate statistical methods. The choice of statistical tests depends on the distribution of the data, the study design, and the availability of measurements at each assessment time point.
Potential significance
The findings may contribute to the evidence supporting conservative physiotherapy management of acute pes anserine bursitis. Comparing these interventions may help physiotherapists make informed treatment decisions based on improvements in pain and knee-related function.
417 studies on the registry are indexed under Bursitis; 112 are open to participants now.
This study's enrollment of 32 is below the median of 45 across 376 interventional studies indexed under Bursitis.
Browse Bursitis studies →Dr Aneeqa Sultan is the lead sponsor of 2 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Participants will use a medial-support knee brace daily for 6-8 hours during mobility for 8 weeks. The intervention aims to reduce pain and improve functional ability in patients with acute pes anserine bursitis.
Device: Medial-Support Knee Brace
Participants will receive a structured exercise program targeting the quadriceps and hamstring muscles. Supervised sessions will be conducted three times per week for 8 weeks, with 3 sets of 10-15 repetitions. Exercises will progress from low to moderate intensity according to participant tolerance.
Behavioral: Eccentric Loading Exercise
Participants will use a medial-support knee brace daily for 6-8 hours during mobility for 8 weeks. The intervention will be used in patients with acute pes anserine bursitis to assess its effects on pain modulation and functional improvement.
Participants will perform a structured exercise program targeting the quadriceps and hamstring muscles for 8 weeks. Supervised sessions will be conducted three times per week, with 3 sets of 10-15 repetitions. Exercise intensity will progress according to participant tolerance.
Change in Pain Intensity Measured by the Visual Analogue Scale (VAS)
Pain intensity will be assessed using the Visual Analogue Scale (VAS) before and after the intervention. Changes in VAS scores will be used to evaluate pain reduction following bracing or eccentric loading exercise in patients with acute pes anserine bursitis.
Time frame: Baseline and after 8 weeks of intervention
Change in Knee Pain and Functional Ability Measured by the WOMAC Index
Knee-related pain and functional ability will be assessed using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) before and after the intervention. Changes in WOMAC scores will be used to evaluate improvement following bracing or eccentric loading exercise.
Time frame: Baseline and after 8 weeks of intervention
Plan to share: No
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