ClinicalTrials.gg
Sign In
CompletedNCT07877012Updated Oct 15, 2026

4-7-8 Breathing Before Colonoscopy: Effects on Anxiety, Pain, and Embarrassment

An interventional study of 4-7-8 Breathing Technique in Anxiety and Pain, sponsored by Manisa Celal Bayar University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-10-15.

Sponsored by Manisa Celal Bayar University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year 10 months after the study started (first participant enrolled Nov 2024, registered Oct 2026).
Updated Oct 15, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
104
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
All
01

Study summary

This study aimed to evaluate the effects of the 4-7-8 breathing technique performed before colonoscopy on patients' anxiety, pain, and embarrassment. Colonoscopy is a procedure used to examine the inside of the large intestine and may cause anxiety, discomfort, and embarrassment in some patients.

In this randomized controlled study, 104 patients undergoing colonoscopy were assigned to either an intervention group or a control group. Patients in the intervention group performed the 4-7-8 breathing technique before colonoscopy, while patients in the control group received usual care. Anxiety, pain, and embarrassment were assessed to compare outcomes between the two groups.

This study aimed to evaluate the effects of the 4-7-8 breathing technique performed before colonoscopy on patients' anxiety levels, pain intensity, feelings of embarrassment, and physiological parameters.

02

Conditions studied

  • Anxiety
  • Pain
03

In context

Anxiety Disorders

5,063 studies on the registry are indexed under Anxiety Disorders; 1,408 are open to participants now.

This study's enrollment of 104 is above the median of 80 across 4,339 interventional studies indexed under Anxiety Disorders.

Browse Anxiety Disorders studies →

Lead sponsor

Manisa Celal Bayar University is the lead sponsor of 33 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients were eligible for inclusion if they were aged 18 years or older, had effective verbal communication skills, were scheduled for their first-ever colonoscopy, were fully conscious and oriented, experienced no intraoperative or postoperative complications, had no diagnosed neurological or psychiatric disorders, and agreed to participate voluntarily

Exclusion criteria

Exclusion Criteria:

  • Patients were excluded if they were under 18 years of age, had hearing or speech impairments that would prevent understanding of the breathing technique instructions, regularly used anxiolytics or sedatives, or exhibited abnormal vital sign fluctuations requiring acute medical intervention during or after the procedure.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
104 participants (actual)

Study arms

  • Experimental
    4-7-8 Breathing Exercise Group

    Behavioral: 4-7-8 Breathing Technique

  • No intervention
    Control group

Interventions

  • Behavioral4-7-8 Breathing Technique

    Participants received individualized instruction on the 4-7-8 breathing technique from the principal investigator approximately 30 minutes before colonoscopy. The technique involved inhaling through the nose for 4 seconds, holding the breath for 7 seconds, and exhaling slowly through the mouth for 8 seconds. Participants completed four breathing cycles per set and two sets in total, with an intervention duration of approximately 8-10 minutes. After the exercise, participants rested for 10 minutes in a quiet pre-procedural room before the pre-procedural assessments and sedatio

06

What researchers measure

Primary outcomes

  1. Anxiety Level (State Anxiety Inventory Score)

    Anxiety was assessed using the State-Trait Anxiety Inventory-State subscale (STAI-S) at baseline (T0), immediately before sedation and colonoscopy (T1), and after the procedure when the patient had fully recovered (T2). Scores were compared between the intervention and control groups.

    Time frame: Baseline (T0), immediately before sedation and colonoscopy (T1), and after the procedure following full cognitive recovery (T2).

07

Study locations

1 site
  • Erhan Ergin Kliniği
    Manisa, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Nov 2024 to primary completion in Jun 2025, 6 months.

Of 2,720 non-industry interventional studies with no phase under Anxiety Disorders, half reached primary completion within 13 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 31. This study's 6 months is below that.

Counting every sponsor, half of 2,789 studies reached it within 12 months; a quarter within 5 and three quarters within 30.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 9, 2026
First posted
Oct 15, 2026
StartActual
Nov 30, 2024
Primary completionActual
Jun 1, 2025
CompletionActual
Jun 1, 2025
Last update
Oct 15, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 15, 2026
Show all 1 update
  1. Oct 15, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07877012
Lead sponsor
Manisa Celal Bayar University
Responsible party
Sponsor
First posted
Oct 15, 2026
Start date
Nov 30, 2024
Primary completion
Jun 1, 2025
Completion
Jun 1, 2025
Last update
Oct 15, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Anxiety Disorders →

Other studies from this sponsor

Manisa Celal Bayar University

Start the discussion