An interventional study of Chrysin LipoMicel in Physiologic Changes, Exercise and Physiological Changes (Heart Rate), sponsored by Isura. Completed at 1 site in Canada. Open to participants aged 21 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-13.
Sponsored by Isura · Not applicable, Interventional, and Treatment
Among 705 studies in Motor Activity with a site in Canada — 140 open to participants now, 168 under way, 2 of them phase 3. Motor Activity · Canada.
Among the 705 studies in Motor Activity with a site in Canada, this one is the 578th largest by enrollment of the 661 interventional ones, is one of 39 that started in 2025, is one of 570 with no phase, and was the 703rd registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
This study's enrollment of 15 is below the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Browse Motor Activity studies →140 of the 705 studies in Motor Activity with a site in Canada are open now, in 2 countries. Each count lists the studies.
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 21 Years to 65 Years · all sexes · healthy volunteers too.
The full table on the hub →705 studies; the count open now beside each. This study's row is marked.
First in 1997; this study’s year is marked. 39 started in 2025.
Median enrollment 46 across the 661 interventional studies, 50 across the 42 observational. Of the 473 that completed or were terminated, 41 (9%) have results posted.
12 of 705 have an industry lead sponsor. The 10 most frequent:
Isura is the lead sponsor of 6 studies on the registry; none are open to participants now.
Isura has 1 study filed under Motor Activity — fewer than ten, so there is no comparison to draw.
42 of the studies in Motor Activity with a site in Canada that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07717710University of British ColumbiaIvabradine for Heart Rate Reduction During Exercise in Healthy Adults | 2026-12 |
| NCT04078334Université du Québec a MontréalPersonalized Exercises Program Prescription to Prevent Functional Decline Throughout Older Adults Hospitalization | 2026-12 |
| NCT04970888Montreal Heart InstituteComparing the Effects of Combining Cognitive and Physical Exercise Training on Cognition, and Cerebral Blood Flow Regulation in Men and Women With Chronic Heart Failure | 2026-12-01 |
| NCT04426786Pacific Parkinson's Research CentreExercise & Brain Energetics in PD | 2026-12-30 |
| NCT07389837Université de MontréalMaple Syrup Carbohydrate Dose-Response on 20-km Cycling Time-Trial Performance | 2026-12-30 |
Among the 705 studies in Motor Activity with a site in Canada, from their registry updates:
This single-arm pilot study evaluates within-subject changes in aerobic capacity, heart rate responses, cycling power output, and related physiological measures in healthy adults during and after 30 days of supplementation with a chrysin-based multi-flavonoid LipoMicel formulation containing chrysin, quercetin, and rutin.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Each participant received a daily dose of a micellar chrysin-based multi-flavonoid formulation once daily for 30 days, providing a total daily dose of 1000 mg chrysin, 240 mg quercetin, and 230 mg rutin. On study visit days participants were instructed to take the intervention after completing a cardiopulmonary exercise testing sessions. No specific instructions were given regarding intake with or without food. Physiological assessments were performed at each study visit.
Dietary Supplement: Chrysin LipoMicel
A maximum oral dose of 1000mg chrysin.
Change in maximal oxygen uptake (VO2max)
VO₂max assessed during standardized incremental indoor cycling-based cardiopulmonary exercise testing. VO₂max is defined as the highest step-averaged oxygen uptake value achieved during the incremental cycling test.
Time frame: Day -7, 0, 14, 31, 45
Change in maximum heart rate (HRmax)
To assess within-subject changes in maximum heart rate, defined as the highest heart rate recorded during the standardized incremental cycling test, in healthy adult volunteers receiving the chrysin-based LipoMicel formulation.
Time frame: Day -7, 0, 14, 31, 45
Zone 2 heart rate (Zone 2 HR)
To assess changes in Zone 2 heart rate, defined as the heart rate corresponding to approximately 60-70% of individual HRmax during standardized incremental cycling testing.
Time frame: Day -7, 0, 14, 31, 45
Maximum cycling power output (Max Power)
To assess changes in maximum cycling power output, defined as the highest power output in watts successfully completed during standardized incremental cycling testing.
Time frame: Day -7, 0, 14, 31, 45
Change in maximal minute ventilation (Max Ve)
To assess within-subject changes in maximal minute ventilation, defined as the highest minute ventilation recorded during the standardized incremental cycling test, in healthy adult volunteers receiving the chrysin-based LipoMicel formulation.
Time frame: Day -7, 0, 14, 31, 45
Plan to share: No
No publications or documents are linked to this record.
Ran from Jan 2025 to primary completion in Oct 2025, 9 months.
Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 9 months is below that.
Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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Isura