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Not yet recruitingNCT07866937peppermintUpdated Oct 8, 2026

Peppermint and Decongestant Technique on Chronic Sinusitis

An interventional study of Sinus self-massage and inhalation of steated boiled peppermint in Sinus Disease, sponsored by Assiut University. Not yet recruiting. Open to participants aged 65 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-10-08.

Sponsored by Assiut University · Not applicable, Interventional, and Treatment

Updated Oct 8, 2026Newly registeredGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
108
Allocation
Randomized
Ages
65 Years to 80 Years
Sex
All
01

Study summary

Chronic rhinosinusitis (CRS) is defined as persistent symptomatic inflammation of the nasal and sinus mucosa that lasts more than 3 months. Epidemiologic studies estimate that 10% to 15% of the US population has CRS with a prevalence of up to 12% in Western populations. CRS is defined as the symptomatic inflammation of the nose and para nasals in uses with the distinction based on the duration of the complaints. CRS is typically described more broadly as an inflammatory disorder and the importance of specific microbial agents in driving the process remains controversial. It is not clear what medical therapy should be followed as the proper treatment for CRS. The most common treatment of CRS includes medical therapy and in cases resistant to medication, endoscopic sinus surgery might be an option. (Kamaneh et al., 2020).

Read the detailed description

CRS is mostly treated by antibiotics and intranasal steroids but due to limited evidence, results of treatment are unsatisfactory. Previous studies have not confirmed the efficiency of herbal medicine to treat rhinosinusitis, particularly in chronic cases. New investigations recommend that some herbal medicines, either alone or combined with other kinds of treatment might alleviate the symptoms of severe sinus infection (Pleis et al.,2010).

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Conditions studied

  • Sinus Disease
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In context

Paranasal Sinus Diseases

45 studies on the registry are indexed under Paranasal Sinus Diseases; 16 are open to participants now.

This study's planned enrollment of 108 is above the median of 80 across 28 interventional studies indexed under Paranasal Sinus Diseases.

Browse Paranasal Sinus Diseases studies →

Lead sponsor

Assiut University is the lead sponsor of 5,050 studies on the registry; 2,174 are open to participants now.

Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 1- Elderly patients able to communicate. 2- Elderly patients have chronic rhinosinusitis

Exclusion criteria

Exclusion Criteria:

  • Hypersensitivity 2-Bronchial asthma and spasmophilia 3- Gastroesophageal reflux disease (heartburn)
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
108 participants (estimated)

Study arms

  • Experimental
    study

    The patient should inhale steam from boiled mint leaves twice daily and perform Sinus Self-Massage to relieve nasal and sinus congestion, in addition to taking the prescribed medications.

    Behavioral: Sinus self-massage and inhalation of steated boiled peppermint

  • No intervention
    control

    routine hospital care

Interventions

  • BehavioralSinus self-massage and inhalation of steated boiled peppermint

    The patient should inhale steam from boiled mint leaves twice daily and perform Sinus Self-Massage to relieve nasal and sinus congestion, in addition to taking the prescribed medications.

06

What researchers measure

Primary outcomes

  1. rhinosinusitis-specific scale

    the 22-item Sino Nasal Outcome Test (SNOT-22) will be used for measuring quality of life. Each item is categorized into 6 levels (0 for no problem to 5 for the problem is as bad as it can be). The total score is gained by adding the score of each item (range 0-110) with lower scores implying a better health-related quality of life. It covers a wide range of health-related quality of life that may affect patient outcomes. SNOT subscales include 5 questions on rhinological symptoms, 4 questions on ear/facial symptoms, 3 questions on sleep function and 6 questions on psychological function. As with the total SNOT scale, higher scores indicate worse symptoms and lower quality of life

    Time frame: 3 months

  2. Visual Analog Pain Scale

    It was adopted from Chiarotto et al. (2019) and used by the researcher to assess the severity of low back pain. Scoring system: The total scores of the visual analog pain scale ranged from (0-10);

    Time frame: 3 months

07

Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Oct 2026; primary completion for Dec 2027, 14 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 5, 2026
First posted
Oct 8, 2026
StartEst.
Oct 1, 2026
Primary completionEst.
Dec 1, 2027
CompletionEst.
Dec 1, 2027
Last update
Oct 8, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 8, 2026
Show all 1 update
  1. Oct 8, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

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Registry details

Key details

Study ID
NCT07866937
Lead sponsor
Assiut University
Responsible party
Tasneem ahmed (lecterurer, Assiut University) — Principal investigator
First posted
Oct 8, 2026
Start date
Oct 1, 2026 (estimated)
Primary completion
Dec 1, 2027 (estimated)
Completion
Dec 1, 2027 (estimated)
Last update
Oct 8, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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