An observational study in Nasal Neoplasm, Nasal Neoplasm Benign and Skull Base Neoplasms, sponsored by University Medical Centre Ljubljana. Recruiting at 1 site in Slovenia. Per ClinicalTrials.gov, last updated 2026-04-29.
Sponsored by University Medical Centre Ljubljana · Observational
This observational prospective clinical study aims to describe the epidemiology, management and outcome of patients with sinonasal and skull-base pathology (tumours and diseases with malignant clinical characteristics) in a tertiary otorhinolaryngology referral centre. The main questions it aims to answer are:
Sinonasal tumours and tumours that involve the adjacent skull base are rare entities. However, their management necessitates a special knowledge of ENT areas and specifics of sinonasal anatomy and skull base. Due to the heterogeneity of pathological diagnoses of sinonasal and skull-base tumours, one of the main aims of this study is to provide epidemiological characteristics in our geographical area. Furthermore, to compare with other tertiary referral centres, we will analyse management results, which could improve the management of these diseases. Since the sinonasal area and skull base house several important neuroanatomical structures and senses, we aim to provide an analysis of the patient-reported quality of life.
The study population will be recruited from patients referred to the tertiary otorhinolaryngology referral centre. The referral applies to the in-hospital or outpatient setting.
Exclusion Criteria:
Absence of the disease
Absence of the disease after the treatment has been completed
Time frame: twelve months after the treatment completion
Overall survival
Survival after the treatment has been completed
Time frame: twelve months after the treatment completion
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Nose Neoplasms
University Medical Centre Ljubljana