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CompletedNCT07863349Updated Oct 7, 2026

Physical Activity and Quality of Life After Liver Paired Exchange Transplantation

An observational study in Liver Transplantation (LT), sponsored by İlker DEMİR. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-07.

Sponsored by İlker DEMİR · Observational

Updated Oct 7, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
68
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 995 studies in Motor Activity with a site in Turkey — 196 open to participants now, 225 under way, none of them phase 3. Motor Activity · Turkey.

Enrollment
118th of 227
68 · median 70
Started
2025
with 147 others
Observational
227 of 995
36 open now
Registered
981st of 995
by date

Among the 995 studies in Motor Activity with a site in Turkey, this one is the 118th largest by enrollment of the 227 observational ones that give a count, is one of 148 that started in 2025, is one of 227 observational ones, and was the 981st registered.

Motor Activity

9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.

Browse Motor Activity studies →

Open to participants now

196 of the 995 studies in Motor Activity with a site in Turkey are open now. Recruiting first, the newest first:

191 more — sign in →

All 196 open studies →

A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →

Who these studies take

Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.

This study: 18 Years and older · all sexes · no healthy volunteers.

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02

Study summary

This prospective longitudinal observational study evaluated changes in physical activity, cognitive function, functional exercise capacity, and health-related quality of life in adult recipients following liver paired exchange (LPE) transplantation. Participants were assessed at 3 and 12 months after transplantation. Physical activity was evaluated using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), cognitive function using the Montreal Cognitive Assessment (MoCA), health-related quality of life using the Short Form-36 (SF-36), and functional exercise capacity using the Six-Minute Walk Test (6MWT). The study aimed to describe changes in these outcomes during the first year following LPE transplantation.

03

Conditions studied

  • Liver Transplantation (LT)

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Keywords

  • Liver Paired Exchange
  • Liver Paired Exchange Transplantation
  • Physical Activity
  • Quality of Life
  • Cognitive Function
  • Functional Exercise Capacity
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adult liver transplant recipients who underwent liver paired exchange (LPE) transplantation at the Liver Transplant Institute Hospital of Inonu University, Malatya, Türkiye. Participants were prospectively evaluated at 3 and 12 months after transplantation.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Underwent liver paired exchange (LPE) transplantation
  • Aged 18 years or older
  • Voluntarily agreed to participate in the study
  • Breathing spontaneously
  • Able to cooperate and follow instructions
  • Hemodynamically stable
  • Able to comply with the study assessments

Exclusion criteria

Exclusion Criteria:

  • Underwent multi-organ transplantation
  • Underwent multi-organ transplantation
  • Had comorbid conditions that prevented completion of the assessments
  • Had orthopedic disorders affecting mobility
  • Unable to complete the assessments due to health-related or other reasons
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
68 participants (actual)
Patient registry
No

Groups and cohorts

  • Liver Paired Exchange Transplant Recipients

    Adult recipients who underwent liver paired exchange (LPE) transplantation were included in this cohort. Participants were evaluated at 3 and 12 months after transplantation. No study-specific intervention was administered.

    Other: Post-Transplant Follow-up Assessments

Interventions

  • OtherPost-Transplant Follow-up Assessments

    Participants who had undergone liver paired exchange transplantation were prospectively followed and evaluated at 3 and 12 months after transplantation. Physical activity, cognitive function, health-related quality of life, and functional exercise capacity were assessed. No therapeutic, surgical, or rehabilitation intervention was assigned as part of the study.

06

What researchers measure

Primary outcomes

  1. Cognitive Function

    Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). The total MoCA score ranges from 0 to 30, with higher scores indicating better cognitive function.

    Time frame: At 3 months and 12 months after liver transplantation

  2. Physical Activity Level

    Physical activity was assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF). The IPAQ-SF assesses walking, moderate-intensity physical activity, vigorous-intensity physical activity, and sitting time during the previous 7 days. Physical activity levels were calculated according to the IPAQ-SF scoring procedure.

    Time frame: At 3 months and 12 months after liver transplantation

  3. Health-Related Quality of Life

    Health-related quality of life was assessed using the Short Form-36 (SF-36). The SF-36 evaluates eight dimensions of health. Scores range from 0 to 100, with higher scores indicating better health-related quality of life.

    Time frame: At 3 months and 12 months after liver transplantation

  4. Functional Exercise Capacity

    Functional exercise capacity was assessed using the Six-Minute Walk Test (6MWT). The distance walked during the test was recorded in meters, with a greater walking distance indicating better functional exercise capacity.

    Time frame: At 3 months and 12 months after liver transplantation

07

Study locations

1 site
  • Inonu University Turgut Ozal Medical Center
    Malatya, 44090, Turkey (Türkiye)
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be publicly shared due to participant confidentiality and data protection considerations.

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Apr 2025 to primary completion in Jul 2026, 15 months.

Of 490 non-industry observational studies under Motor Activity, half reached primary completion within 22 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 48. This study's 15 months is below that.

Counting every sponsor, half of 500 studies reached it within 22 months; a quarter within 8 and three quarters within 48.

How these figures are worked out, and which studies are left out of them.

Registered
Oct 2, 2026
First posted
Oct 7, 2026
StartActual
Apr 1, 2025
Primary completionActual
Jul 1, 2026
CompletionActual
Jul 1, 2026
Last update
Oct 7, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Oct 7, 2026
Show all 1 update
  1. Oct 7, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07863349
Lead sponsor
İlker DEMİR
Responsible party
İlker DEMİR (Physiotherapist, PhD, Hasan Kalyoncu University) — Sponsor-investigator
First posted
Oct 7, 2026
Start date
Apr 1, 2025
Primary completion
Jul 1, 2026
Completion
Jul 1, 2026
Last update
Oct 7, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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