An interventional study of Standard program and Plyometrics Training in Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation and Anterior Cruciate Ligament/Surgery, sponsored by Cairo University. Recruiting at 1 site in Egypt. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-10-15.
Sponsored by Cairo University · Not applicable, Interventional, and Treatment
The primary goal of this RCT is to evaluate the effect of adding plyometric training on standard program intervention in patients aged 18-40 years who have undergone ACLR surgery.
The primary question to answer is does adding plyometrics training to the standard rehabilitation program has superior effect in the improvement of muscular strength, dynamic balance and functional performance in ACLR patients. Participants will be divided into two groups. Group 1 (control) receives standard program for 24 weeks, and Group 2 (interventional) receives the same standard program for 16 weeks, followed by adding plyometrics for additional 8 weeks alongside with the standard program (total of 24 weeks).
Achieving full recovery after ACLR is still challenging as persistent deficits of muscular strength have still reported. Plyometrics consists of rapid muscle stretch (eccentric action) followed immediately by a shortening (concentric action) of the same muscle and connective tissue.
This study hypothesizes that adding plyometric training to standard physiotherapy will improve muscular strength, proprioception, dynamic balance and functional performance
Cairo University is the lead sponsor of 4,909 studies on the registry; 1,445 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
The subjects will receive standard rehabilitation program.
Other: Standard program
The subjects will receive Plyometrics Training added to the standard rehabilitation program.
Other: Standard program · Other: Plyometrics Training
Participants will receive only standard therapy for 24 weeks.
Participants will receive standard therapy for 16 weeks, followed by an additional 8 weeks of plyometrics training alongside with standard therapy. (total=24 weeks).
Joint Position Sense (JPS)
JPS was assessed by the Biodex System 4Pro isokinetic dynamometer by the Active Angle Reproduction technique (AAR) with eyes closed. The measurements are taken along 30° and 60° for both involved and uninvolved legs. The mean reproduced angle value is calculated at each angle to then calculate the JPS error. The smaller the error, the better the participant's perception of joint position is.
Time frame: Baseline (week 16), post-intervention (week 24) and follow up (week 32).
Dynamic Stability
Y-Balance Test is used to assess stability and balance in different directions. It is performed by leg reaches along 3 dimensions: anterior, posteromedial and posterolateral. The participant stands on one leg and reaches as far as possible with the second one along all three dimensions.
Time frame: Baseline (week 16), post-intervention (week 24) and follow up (week 32).
Isokinetic Quadriceps Peak Torques Normalized to Body Weight
The peak torque of quadriceps at 60°/s and 180°/s is considered as the highest peak torque along the 5 repetitions, each. It is then normalized to body mass by the following equation: PTrelative = Peak Torque (Nm) / Body Mass (kg).
Time frame: Baseline (week 16), post-intervention (week 24) and follow up (week 32).
Functional Performance test
For the distance tests (single-leg, triple ho, crossover hop), the longest distance (cm) is the best and is measured in centimeters using calibrated floor markings. For the time related test (6-meter timed hop), the shortest time (s) is considered and is measured using a digital stopwatch. For all four hop tests, 3 trials will be performed. The best trial will be taken to statistical analysis.
Time frame: Baseline (week 16), post-intervention (week 24) and follow up (week 32).
Plan to share: No
Start is estimated for Oct 2026; primary completion for Apr 2027, 6 months later.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.