An observational study in Vital Pulp Therapy, sponsored by Cairo University. Not yet recruiting. Open to participants aged 10 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-10-26.
Sponsored by Cairo University · Observational
Predicting the success of vital pulp therapy remains a clinical challenge. There is a knowledge gap regarding the relationship between age, inflammasome related proteins expression , and clinical/radiographic outcomes. Therefore, the effect of age on will be evaluated, and their predictive value for clinical and radiographic outcomes will be assessed in a prospective cohort study.
Cairo University is the lead sponsor of 4,909 studies on the registry; 1,445 are open to participants now.
Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients ,aged from 10 to 60 years, have permanent mature posterior teeth diagnosed with symptomatic irreversible pulpitis with normal periapical condition and will undergo a standardized complete pulpotomy protocol.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
patient aged (10 - 25 years)
Procedure: Standardized complete pulpotomy protocol
patient aged (26 - 40 years)
Procedure: Standardized complete pulpotomy protocol
patient aged (41 - 60 years)
Procedure: Standardized complete pulpotomy protocol
Standardized complete pulpotomy protocol
Clinical success
Tool: Resolution of clinical signs and symptoms, no swelling and/or no sinus tract.
Time frame: After 6 months and 12 months.
Radiographic success
Tool: Absence of periapical radiolucency, periodontal ligament space widening, internal or external root resorption, and other radiographic signs of endodontic failure
Time frame: After 6 months and 12 months.
Inflammasome-related proteins expression levels
Tool: Enzyme-Linked Immunosorbent Assay
Time frame: After 2 weeks
Dentin bridge
Tool: Cone Beam Computed Tomography
Time frame: After 6 months and 12 months.
No study locations are listed for this record.
Start is estimated for Oct 2026; primary completion for Dec 2027, 14 months later.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.
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