An interventional study of Foam rolling after total knee arthroplasty and Standard home exercise program after total knee arthroplasty in Total Knee Arthroplasty Recovery, Total Knee Arthroplasty Postoperative Pain and Total Knee ArthroplastyKnee Pain, Functionality, sponsored by Dokuz Eylul University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2026-10-02.
Sponsored by Dokuz Eylul University · Not applicable, Interventional, and Treatment
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Among 1,095 studies in Pain, Postoperative with a site in Turkey — 264 open to participants now, 296 under way, none of them phase 3. Pain, Postoperative · Turkey.
Among the 1,095 studies in Pain, Postoperative with a site in Turkey, this one is the 862nd largest by planned enrollment of the 880 interventional ones that give a count, is one of 220 that started in 2026, is one of 811 with no phase, reaches primary completion later than 285 of the 295 other live ones, and was the 1,043rd registered.
5,644 studies on the registry are indexed under Pain, Postoperative; 1,231 are open to participants now.
Browse Pain, Postoperative studies →264 of the 1,095 studies in Pain, Postoperative with a site in Turkey are open now. Recruiting first, the newest first:
Kocaeli City Hospital · Sites in Turkey
Ages 8–18 · Healthy volunteers
Bursa City Hospital · Sites in Turkey
Ages 18–85 · Women only
Van Training and Research Hospital · Sites in Turkey
Ages 18–65
Istanbul University · Sites in Turkey
Ages 1–12
Ankara City Hospital Bilkent · Sites in Turkey
Ages 60+ · Healthy volunteers
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 679 Pain, Postoperative studies recruiting now, 240 (35%) set no upper age limit and 329 (48%) stop at 75 or younger; 74 take children under 18; 128 take healthy volunteers.
This study: 40 Years and older · all sexes · no healthy volunteers.
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1,095 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 5 · Phase 2 4 · Phase 3 2 · Phase 4 59
First in 2009; this study’s year is marked. 220 started in 2026.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 26 is below the median of 75 across 4,829 interventional studies indexed under Pain, Postoperative.
Median enrollment 70 across the 880 interventional studies, 80 across the 215 observational. Of the 748 that completed or were terminated, 9 (1%) have results posted.
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2 of 1,095 have an industry lead sponsor. The 10 most frequent:
Dokuz Eylul University is the lead sponsor of 261 studies on the registry; 35 are open to participants now.
Dokuz Eylul University has 3 studies filed under Pain, Postoperative — fewer than ten, so there is no comparison to draw.
133 of the studies in Pain, Postoperative with a site in Turkey that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07659990Ferit YetikRISS Versus SPSIP Block in Modified Radical Mastectomy | 2026-11 |
| NCT07524673Cumhuriyet UniversityComprasion of SPSIP and Rhomboid Intercostal Plan Blocks on VATS | 2026-11 |
| NCT07561853Sakarya UniversitySerratus Posterior Superior vs Erector Spinae Plane Block for Breast Surgery | 2026-11-15 |
| NCT07650877Ankara City Hospital BilkentComparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block | 2026-11-20 |
| NCT07436806Medipol UniversitySPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery | 2026-11-20 |
Add all 133 to your calendar (.ics) → With an account.
Among the 1,095 studies in Pain, Postoperative with a site in Turkey, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The aim of this study is to investigate the effects of foam rolling in patients who have undergone total knee arthroplasty on pain, knee mobility, leg muscle strength, the ability to sense joint position, fear of movement, walking, balance, and the ability to perform daily activities.
A total of 26 patients, with 13 patients in each group, will be included in the study. Participants will be randomly assigned to two groups. One group will receive the routine rehabilitation program, while the other group will receive foam rolling in addition to the routine rehabilitation program.
Foam rolling and rehabilitation exercises will be taught at the Dokuz Eylül University Orthopedics and Traumatology Outpatient Clinic, and you will be asked to perform these exercises at home. The foam rolling group will perform foam rolling 6 days per week, 2 sets per day, with 3 repetitions of 60 seconds each. The control group will not perform foam rolling and will follow the routine rehabilitation program.
The standard rehabilitation program will consist of strengthening exercises in different directions for the entire leg, range-of-motion exercises, stretching exercises, and walking exercises. You will be asked to perform the exercises for 3 sets of 10 repetitions per day.
The assessments in the study will be performed at the second postoperative week (test 1), sixth postoperative week (test 2), and fourteenth postoperative week (test 3). These time points are also times when you would normally visit your doctor for routine follow-up; therefore, you will not be expected to make any additional hospital visits for the study.
The study will continue for 1 year, and each patient will be followed for 14 weeks.
Pain will be assessed using a single-question questionnaire. Walking, functional level, and leg muscle strength will be assessed using short performance tests involving sitting-to-standing and walking activities, as well as a questionnaire. Knee joint range of motion and proprioception will be assessed by measuring the angles of your knee using a ruler-like plastic device. Fear of movement will be assessed using a short questionnaire.
All assessments will take no more than 20 minutes. The results will be determined by examining whether there are differences in these measurements between the different assessment time points.
The aim of this study is to investigate the effects of foam rolling after total knee arthroplasty on pain, range of motion, muscle strength, proprioception, kinesiophobia, gait, balance, and functional level.
All patients will receive education regarding postoperative pain management, exercises, foam rolling, and the rehabilitation program to be implemented. Both the rehabilitation exercises and foam rolling will be taught to the patients by physiotherapists in the outpatient clinic and performed by the patients at home as part of their home program. The foam rolling intervention group will perform foam rolling for 4 weeks starting from the second postoperative week, 3 days per week, 1 set per day, with 3 repetitions of 60 seconds each. The control group will not perform foam rolling and will follow the standard home exercise program.
The standard home exercise program will consist of lower-extremity range-of-motion exercises, isometric exercises, stretching exercises for the knee joint, and straight leg raise exercises in different directions. Patients will be instructed to perform these exercises for 3 sets of 10 repetitions per day. In addition, patients will be encouraged to mobilize both indoors and outdoors.
Outcome assessments will be performed at the second postoperative week (test 1), sixth postoperative week (test 2), and fourteenth postoperative week (test 3).
Demographic and clinical characteristics, including age, gender, height, body weight, and body mass index, will be recorded on the data collection form. Clinical assessments will include pain level, range of motion, muscle strength, proprioception, kinesiophobia, gait, balance, and functional level. Maximum isometric muscle strength will be assessed only at the fourteenth postoperative week (test 3).
Pain will be assessed using the Visual Analog Scale (VAS). The maximum isometric muscle strength of the quadriceps femoris and hamstring muscles will be assessed using manual muscle testing and a hand-held dynamometer. Range of motion will be assessed using a plastic manual goniometer. Knee joint proprioception will be assessed using the active joint repositioning test at target angles of 30° and 60° of knee flexion. The Hospital for Special Surgery (HSS) Knee Score will be used to evaluate knee arthroplasty outcomes. Kinesiophobia will be assessed using the self-reported Tampa Scale for Kinesiophobia. The Timed Up and Go Test and the Five-Times Sit-to-Stand Test will be used to assess lower-extremity function, functional mobility, gait, and balance.
5,644 studies on the registry are indexed under Pain, Postoperative; 1,231 are open to participants now.
This study's planned enrollment of 26 is below the median of 75 across 4,829 interventional studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →Dokuz Eylul University is the lead sponsor of 261 studies on the registry; 35 are open to participants now.
Compared within Pain, Postoperative, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Pain. The counts are of registry records indexed under each term, refreshed daily. How we classify →
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Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The foam rolling intervention group will perform foam rolling for 4 weeks starting from the second postoperative week, 3 days per week, 1 set per day, with 3 repetitions of 60 seconds each.
Other: Foam rolling after total knee arthroplasty
The control group will not perform foam rolling and will follow the standard home exercise program. The standard home exercise program will consist of lower-extremity range-of-motion exercises, isometric exercises, stretching exercises for the knee joint, and straight leg raise exercises in different directions. Participants will be instructed to perform the exercises for 3 sets of 10 repetitions per day.
Other: Standard home exercise program after total knee arthroplasty
The foam rolling intervention will be performed for 4 weeks starting from the second postoperative week, 3 days per week, 1 set per day, with 3 repetitions of 60 seconds each.
The control group will not perform foam rolling and will follow the standard home exercise program. The standard home exercise program will consist of lower-extremity range-of-motion exercises, isometric exercises, stretching exercises for the knee joint, and straight leg raise exercises in different directions. Participants will be instructed to perform the exercises for 3 sets of 10 repetitions per day.
Change from baseline at week 14 in knee pain
Pain will be assessed using the 10-cm Visual Analog Scale (VAS), scored from 0 (no pain) to 10 (unbearable pain).
Time frame: From enrollment to the end of the 14-week period
Change from baseline at week 14 in knee range of motion
Knee range of motion will be measured using a 30-cm transparent plastic manual goniometer.
Time frame: From enrollment to the end of the 14-week period
Change from baseline at week 14 in muscle strength
Maximum isometric strength of the quadriceps femoris and hamstring muscles will be measured using a hand-held dynamometer and muscle strength will also be assessed using manual muscle testing.
Time frame: From enrollment to the end of the 14-week period
Change from baseline at week 14 in knee joint proprioception
Knee proprioception will be assessed using the active joint repositioning test at 30° and 60° knee flexion, with the absolute difference between the target and reproduced angles recorded.
Time frame: From enrollment to the end of the 14-week period
Change from baseline at week 14 in kinesiophobia
Kinesiophobia will be assessed using the 17-item Turkish version of the Tampa Scale for Kinesiophobia. Each item will be scored using a 4-point Likert scale ranging from 1 to 4.
Time frame: From enrollment to the end of the 14-week period
Change from baseline at week 14 in Timed Up and Go Test performance
Gait, balance, and functional mobility will be assessed using the Timed Up and Go Test. The patient will be asked to stand up from a chair, walk 3 meters, turn around, and sit back down. The completion time will be recorded in seconds.
Time frame: From enrollment to the end of the 14-week period
Change from baseline at week 14 in Five Times Sit-to-Stand Test performance
Lower-extremity strength, balance, and functional level will be assessed using the Five Times Sit-to-Stand Test. The patient will be asked to stand up and sit down five times as quickly and safely as possible, and the completion time will be recorded in seconds.
Time frame: From enrollment to the end of the 14-week period
Change from baseline at week 14 in Hospital for Special Surgery Knee Score
Knee function will be assessed using the Hospital for Special Surgery Knee Score. The Hospital for Special Surgery (HSS) Knee Score will be rated on a 0-100-point scale, with scores of ≥85 indicating excellent, 70-84 good, 60-69 moderate, and ≤59 poor knee function.
Time frame: From enrollment to the end of the 14-week period
Plan to share: No — Individual participant data will not be shared because the study does not plan to make individual-level participant data available to other researchers.
Started Sep 2026 (actual). Primary completion is estimated for Dec 2027, 15 months after the start.
Of 2,096 non-industry interventional studies with no phase under Pain, Postoperative, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 23. This study's planned 15 months is above that.
Counting every sponsor, half of 2,109 studies reached it within 11 months; a quarter within 6 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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