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RecruitingNCT07848126Updated Sep 29, 2026

Effect of Foam Rolling After Total Knee Arthroplasty

An interventional study of Foam rolling after total knee arthroplasty and Standard home exercise program after total knee arthroplasty in Total Knee Arthroplasty Recovery, Total Knee Arthroplasty Postoperative Pain and Total Knee ArthroplastyKnee Pain, Functionality, sponsored by Dokuz Eylul University. Recruiting at 1 site in Turkey (Türkiye). Open to participants aged 40 Years and older. Per ClinicalTrials.gov, last updated 2026-09-29.

Sponsored by Dokuz Eylul University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
26
Allocation
Randomized
Ages
40 Years and older
Sex
All
01

Study summary

The aim of this study is to investigate the effects of foam rolling in patients who have undergone total knee arthroplasty on pain, knee mobility, leg muscle strength, the ability to sense joint position, fear of movement, walking, balance, and the ability to perform daily activities.

A total of 26 patients, with 13 patients in each group, will be included in the study. Participants will be randomly assigned to two groups. One group will receive the routine rehabilitation program, while the other group will receive foam rolling in addition to the routine rehabilitation program.

Foam rolling and rehabilitation exercises will be taught at the Dokuz Eylül University Orthopedics and Traumatology Outpatient Clinic, and you will be asked to perform these exercises at home. The foam rolling group will perform foam rolling 6 days per week, 2 sets per day, with 3 repetitions of 60 seconds each. The control group will not perform foam rolling and will follow the routine rehabilitation program.

The standard rehabilitation program will consist of strengthening exercises in different directions for the entire leg, range-of-motion exercises, stretching exercises, and walking exercises. You will be asked to perform the exercises for 3 sets of 10 repetitions per day.

The assessments in the study will be performed at the second postoperative week (test 1), sixth postoperative week (test 2), and fourteenth postoperative week (test 3). These time points are also times when you would normally visit your doctor for routine follow-up; therefore, you will not be expected to make any additional hospital visits for the study.

The study will continue for 1 year, and each patient will be followed for 14 weeks.

Pain will be assessed using a single-question questionnaire. Walking, functional level, and leg muscle strength will be assessed using short performance tests involving sitting-to-standing and walking activities, as well as a questionnaire. Knee joint range of motion and proprioception will be assessed by measuring the angles of your knee using a ruler-like plastic device. Fear of movement will be assessed using a short questionnaire.

All assessments will take no more than 20 minutes. The results will be determined by examining whether there are differences in these measurements between the different assessment time points.

Read the detailed description

The aim of this study is to investigate the effects of foam rolling after total knee arthroplasty on pain, range of motion, muscle strength, proprioception, kinesiophobia, gait, balance, and functional level.

All patients will receive education regarding postoperative pain management, exercises, foam rolling, and the rehabilitation program to be implemented. Both the rehabilitation exercises and foam rolling will be taught to the patients by physiotherapists in the outpatient clinic and performed by the patients at home as part of their home program. The foam rolling intervention group will perform foam rolling for 4 weeks starting from the second postoperative week, 3 days per week, 1 set per day, with 3 repetitions of 60 seconds each. The control group will not perform foam rolling and will follow the standard home exercise program.

The standard home exercise program will consist of lower-extremity range-of-motion exercises, isometric exercises, stretching exercises for the knee joint, and straight leg raise exercises in different directions. Patients will be instructed to perform these exercises for 3 sets of 10 repetitions per day. In addition, patients will be encouraged to mobilize both indoors and outdoors.

Outcome assessments will be performed at the second postoperative week (test 1), sixth postoperative week (test 2), and fourteenth postoperative week (test 3).

Demographic and clinical characteristics, including age, gender, height, body weight, and body mass index, will be recorded on the data collection form. Clinical assessments will include pain level, range of motion, muscle strength, proprioception, kinesiophobia, gait, balance, and functional level. Maximum isometric muscle strength will be assessed only at the fourteenth postoperative week (test 3).

Pain will be assessed using the Visual Analog Scale (VAS). The maximum isometric muscle strength of the quadriceps femoris and hamstring muscles will be assessed using manual muscle testing and a hand-held dynamometer. Range of motion will be assessed using a plastic manual goniometer. Knee joint proprioception will be assessed using the active joint repositioning test at target angles of 30° and 60° of knee flexion. The Hospital for Special Surgery (HSS) Knee Score will be used to evaluate knee arthroplasty outcomes. Kinesiophobia will be assessed using the self-reported Tampa Scale for Kinesiophobia. The Timed Up and Go Test and the Five-Times Sit-to-Stand Test will be used to assess lower-extremity function, functional mobility, gait, and balance.

02

Conditions studied

  • Total Knee Arthroplasty Recovery
  • Total Knee Arthroplasty Postoperative Pain
  • Total Knee ArthroplastyKnee Pain, Functionality
  • Total Knee Arthroplasty\(TKA\)
  • Foam Roller

Keywords

  • total knee arthroplasty
  • foam roller
  • rondomized controlled trials
03

Who can participate

Ages eligible
40 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Willingness to participate in the study
  • Scheduled for primary total knee arthroplasty
  • Age 40 years or older

Exclusion criteria

Exclusion Criteria:

  • Body mass index (BMI) > 40 kg/m²
  • History of revision surgery in the knee region
  • Any other orthopedic or neurological condition that may cause walking or functional impairment
  • Presence of heart disease or uncontrolled hypertension
  • Presence of neuromuscular or neurodegenerative disease
  • Inability to understand the study protocol instructions
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
26 participants (estimated)

Study arms

  • Experimental
    Foam rolling group

    The foam rolling intervention group will perform foam rolling for 4 weeks starting from the second postoperative week, 3 days per week, 1 set per day, with 3 repetitions of 60 seconds each.

    Other: Foam rolling after total knee arthroplasty

  • Active comparator
    Control group

    The control group will not perform foam rolling and will follow the standard home exercise program. The standard home exercise program will consist of lower-extremity range-of-motion exercises, isometric exercises, stretching exercises for the knee joint, and straight leg raise exercises in different directions. Participants will be instructed to perform the exercises for 3 sets of 10 repetitions per day.

    Other: Standard home exercise program after total knee arthroplasty

Interventions

  • OtherFoam rolling after total knee arthroplasty

    The foam rolling intervention will be performed for 4 weeks starting from the second postoperative week, 3 days per week, 1 set per day, with 3 repetitions of 60 seconds each.

  • OtherStandard home exercise program after total knee arthroplasty

    The control group will not perform foam rolling and will follow the standard home exercise program. The standard home exercise program will consist of lower-extremity range-of-motion exercises, isometric exercises, stretching exercises for the knee joint, and straight leg raise exercises in different directions. Participants will be instructed to perform the exercises for 3 sets of 10 repetitions per day.

05

What researchers measure

Primary outcomes

  1. Change from baseline at week 14 in knee pain

    Pain will be assessed using the 10-cm Visual Analog Scale (VAS), scored from 0 (no pain) to 10 (unbearable pain).

    Time frame: From enrollment to the end of the 14-week period

  2. Change from baseline at week 14 in knee range of motion

    Knee range of motion will be measured using a 30-cm transparent plastic manual goniometer.

    Time frame: From enrollment to the end of the 14-week period

Secondary outcomes

  1. Change from baseline at week 14 in muscle strength

    Maximum isometric strength of the quadriceps femoris and hamstring muscles will be measured using a hand-held dynamometer and muscle strength will also be assessed using manual muscle testing.

    Time frame: From enrollment to the end of the 14-week period

  2. Change from baseline at week 14 in knee joint proprioception

    Knee proprioception will be assessed using the active joint repositioning test at 30° and 60° knee flexion, with the absolute difference between the target and reproduced angles recorded.

    Time frame: From enrollment to the end of the 14-week period

  3. Change from baseline at week 14 in kinesiophobia

    Kinesiophobia will be assessed using the 17-item Turkish version of the Tampa Scale for Kinesiophobia. Each item will be scored using a 4-point Likert scale ranging from 1 to 4.

    Time frame: From enrollment to the end of the 14-week period

  4. Change from baseline at week 14 in Timed Up and Go Test performance

    Gait, balance, and functional mobility will be assessed using the Timed Up and Go Test. The patient will be asked to stand up from a chair, walk 3 meters, turn around, and sit back down. The completion time will be recorded in seconds.

    Time frame: From enrollment to the end of the 14-week period

  5. Change from baseline at week 14 in Five Times Sit-to-Stand Test performance

    Lower-extremity strength, balance, and functional level will be assessed using the Five Times Sit-to-Stand Test. The patient will be asked to stand up and sit down five times as quickly and safely as possible, and the completion time will be recorded in seconds.

    Time frame: From enrollment to the end of the 14-week period

  6. Change from baseline at week 14 in Hospital for Special Surgery Knee Score

    Knee function will be assessed using the Hospital for Special Surgery Knee Score. The Hospital for Special Surgery (HSS) Knee Score will be rated on a 0-100-point scale, with scores of ≥85 indicating excellent, 70-84 good, 60-69 moderate, and ≤59 poor knee function.

    Time frame: From enrollment to the end of the 14-week period

06

Study locations

1 of 1 sites recruiting
  • Dokuz Eylül University
    Izmir, Balçova, Turkey (Türkiye)
    Recruiting
07

References and documents

Publications

  • Yokochi M, Nakamura M, Iwata A, Kaneko R, Yamada N, Konrad A. The acute cross-education effect of foam rolling on the thigh muscles in patients after total knee arthroplasty. Front Rehabil Sci. 2024 Oct 25;5:1433231. doi: 10.3389/fresc.2024.1433231. eCollection 2024. PubMed 39619124 ↗
  • Yokochi M, Nakamura M, Iwata A, Kaneko R, Watanabe S, Konrad A, Yamada N. The acute effect of roller massager on knee joint range of motion and muscle pain in older adults with total knee arthroplasty. J Musculoskelet Neuronal Interact. 2023 Jun 1;23(2):223-227. PubMed 37259662 ↗
  • Konrad A, Nakamura M, Tilp M, Donti O, Behm DG. Foam Rolling Training Effects on Range of Motion: A Systematic Review and Meta-Analysis. Sports Med. 2022 Oct;52(10):2523-2535. doi: 10.1007/s40279-022-01699-8. Epub 2022 May 26. PubMed 35616852 ↗
  • Konrad A, Nakamura M, Paternoster FK, Tilp M, Behm DG. A comparison of a single bout of stretching or foam rolling on range of motion in healthy adults. Eur J Appl Physiol. 2022 Jul;122(7):1545-1557. doi: 10.1007/s00421-022-04927-1. Epub 2022 Mar 17. PubMed 35298696 ↗
  • Yokochi M, Nakamura M, Iwata A, Kaneko R, Watanabe S, Konrad A, Yamada N. A 1-Week Comprehensive Foam Rolling Intervention Program Can Improve Knee Pain but Not Muscle Function and Range of Motion in Patients with Total Knee Arthroplasty. Int J Environ Res Public Health. 2023 Feb 14;20(4):3351. doi: 10.3390/ijerph20043351. PubMed 36834043 ↗

Individual participant data

Plan to share: No — Individual participant data will not be shared because the study does not plan to make individual-level participant data available to other researchers.

08

Registry details

Key details

Study ID
NCT07848126
Lead sponsor
Dokuz Eylul University
Responsible party
Öykü Bulduk (Physiotherapist, Dokuz Eylul University) — Principal investigator
First posted
Sep 29, 2026
Start date
Sep 9, 2026
Primary completion
Dec 2027 (estimated)
Completion
Dec 2027 (estimated)
Last update
Sep 29, 2026

Study contacts

Öykü Bulduk, Physiotherapist
Contact
buldukoyku@gmail.com
+905362743035
Bayram Ünver, Prof. Dr.
Contact
unverbay@gmail.com
Bayram Ünver, Prof. Dr.
study director · Dokuz Eylul University
Vasfi Karatosun, Prof. Dr.
study chair · Dokuz Eylul University
Gonca Cura, Physiotherapist
study chair · Dokuz Eylul University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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