An interventional study of supervised training and daily walking in Knee Osteoarthritis and Oxidative Stress, sponsored by Mariette Boshuis. Recruiting at 1 site in Netherlands. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-29.
Sponsored by Mariette Boshuis · Not applicable, Interventional, and Treatment
A six week patient study that intends to prove that training helps improve the life of people with osteoatritis of the knee.
It looks at pain and function in daily life and markers in the blood that show stress at a cell level.
In this study you will be part of a group one that receives 6 weeks of training (2 sessions per week) or you are part of group two that will exercise by walking 6000 steps per day.
To investigate the effect of the training and walking, there will be an first screening of your capillary blood (by use of a few drops of blood from your finger), and you will be asked to fill in some questionnaires about your symptoms, that will include a painscore and a questionair on your specific complaints. These test will be retaken at the end of your 6 weeks of training.
The study is focussed to benefit you by strengthening the muscles around your knee and improving your overall fitness.
Exclusion Criteria:
the patient will recieve 6 weeks of 2 supevised trainings per week as an outpatient
Other: supervised training
the patient will walk 6000 steps per day for the duration of 6 weeks
Other: daily walking
supervised training by a trained physical therapist, focussed on strength and overall fitness
walking 6000 steps per day unsupervised
NRPS Pain score
numeric pain rating scale
Time frame: 6 weeks
PSPF
Patient Specific Functional Scale
Time frame: 6 weeks
oxidative stress bloodmarkers
d-Roms fast test
Time frame: 6 weeks
Plan to share: No
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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