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Not yet recruitingNCT07845188Updated Sep 28, 2026

Nutritional Status of Gaucher Disease Patients

An observational study in Gaucher Disease, sponsored by Assiut University. Not yet recruiting. Open to participants aged 1 Month and older. Per ClinicalTrials.gov, last updated 2026-09-28.

Sponsored by Assiut University · Observational

Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
84
Ages
1 Month and older
Sex
All
01

Study summary

This cross-sectional study aims to evaluate the nutritional status of patients with Gaucher disease attending Assiut University Children's Hospital using anthropometric measurements and body composition analysis.

Read the detailed description

Gaucher disease is a lysosomal storage disorder that may affect growth and nutritional status, particularly in children. This observational study will include patients with confirmed Gaucher disease (types 1, 2, and 3) who attend follow-up visits at Assiut University Children's Hospital.

Nutritional status will be assessed by detailed dietary history, anthropometric measurements (weight, height, BMI, mid-arm circumference), and body composition analysis using bioelectrical impedance analysis (BIA).

02

Conditions studied

  • Gaucher Disease

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Keywords

  • Gaucher disease
  • Nutritional status
  • Body composition
  • Anthropometry
  • Assiut
03

Who can participate

Ages eligible
1 Month and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with confirmed Gaucher disease attending Assiut University Children's Hospital for follow-up visits.

Inclusion criteria

  • Confirmed diagnosis of Gaucher disease (type 1, 2, or 3)
  • Undergoing a follow-up visit at Assiut University Children's Hospital
  • Written informed consent from caregivers

Exclusion criteria

Exclusion Criteria:

  • Other autosomal recessive lysosomal storage diseases
  • Not undergoing a follow-up visit at Assiut University Children's Hospital
04

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
84 participants (estimated)
Patient registry
No

Groups and cohorts

  • Single cohort: Gaucher Disease Patients

    Patients with confirmed Gaucher disease (types 1, 2, and 3) who will undergo nutritional assessment including anthropometry and body composition analysis.

05

What researchers measure

Primary outcomes

  1. Prevalence of underweight

    Proportion of patients with weight-for-age below -2 standard deviations according to WHO growth charts.

    Time frame: Baseline

Secondary outcomes

  1. Prevalence of stunting

    Proportion of patients with height-for-age below -2 standard deviations according to WHO growth charts.

    Time frame: Baseline

  2. Mean body mass index

    Mean body mass index (BMI) in kg/m².

    Time frame: Baseline

  3. Mean mid-arm circumference

    Mean mid-upper arm circumference in centimeters.

    Time frame: Baseline

  4. Mean fat mass percentage

    Mean fat mass percentage measured by bioelectrical impedance analysis (BIA).

    Time frame: Baseline

  5. Mean lean body mass

    Mean lean body mass measured by bioelectrical impedance analysis (BIA).

    Time frame: Baseline

06

Study locations

No study locations are listed for this record.

07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07845188
Lead sponsor
Assiut University
Responsible party
Salma Hassanein Salem Ahmed (Resident Physician, Department of Pediatrics, Assiut University) — Principal investigator
First posted
Sep 28, 2026
Start date
Sep 26, 2026 (estimated)
Primary completion
Sep 26, 2027 (estimated)
Completion
Feb 25, 2028 (estimated)
Last update
Sep 28, 2026

Study contacts

Salma H Salem, Resident
Contact
Salma.17308823@med.aun.edu.eg
+20 10 14620228
Mostafa M Embaby, prof
study chair · Pediatrics Department, Assiut University Hospitals

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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