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Not yet recruitingNCT07843524Updated Sep 28, 2026

Prevalence and Association of Dysfunctional Breathing With Nicotine Dependence and Physical Activity Among Young Smokers

An observational study in Dysfunctional Breathing, Physical Activity and Nicotine Dependence, sponsored by Istinye University. Not yet recruiting. Open to participants aged 18 Years to 24 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-28.

Sponsored by Istinye University · Observational

Study type
Observational
Model
Other
Time perspective
Cross-sectional
Enrollment
420
Ages
18 Years to 24 Years
Sex
All
01

Study summary

We will structure the study's summary to provide a clear and accessible overview for patients, families, and healthcare providers. The research will examine young adult cigarette smokers aged 18 to 24 to estimate the prevalence of a dysfunctional breathing-compatible symptom pattern using the Nijmegen Questionnaire. Furthermore, the study will assess how nicotine dependence severity-measured via the Fagerström Test for Nicotine Dependence-and physical activity levels-assessed using the International Physical Activity Questionnaire-relate to this symptom burden. We will recruit participants through social media announcements and conduct face-to-face evaluations at Istinye University. The project will employ hierarchical linear and binary logistic regression models, adjusting for age, sex, and body mass index, to determine independent predictors of dysfunctional breathing. Ultimately, the findings will provide valuable insights into the combined impacts of smoking severity and physical activity on respiratory health in young adults.

02

Conditions studied

  • Dysfunctional Breathing
  • Physical Activity
  • Nicotine Dependence

Keywords

  • nicotine dependence
  • Dysfunctional breathing
  • physical activity
03

Who can participate

Ages eligible
18 Years to 24 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study population will consist of young adult cigarette smokers aged 18 to 24 recruited through social media announcements, who will undergo face-to-face evaluation and eligibility assessments at a single center.

Inclusion criteria

  • Being between 18 and 24 years of age.
  • Reporting current cigarette smoking (daily or occasionally) at the time of assessment

Exclusion criteria

Exclusion Criteria:

  • Having a diagnosed personality disorder.
  • Having a substance use disorder.
  • Engaging in regular meditation or breathing exercises.
  • Having a chronic cardiovascular or pulmonary disease.
04

Study design

Observational model
Other
Time perspective
Cross-sectional
Enrollment
420 participants (estimated)
Patient registry
No

Groups and cohorts

  • Young adult cigarette smokers.

    Other: Observational evaluation.

Interventions

  • OtherObservational evaluation.

    This study will not involve any experimental medical treatment or intervention. It will be an observational evaluation where participants will complete self-report instruments, including the Fagerström Test for Nicotine Dependence, the International Physical Activity Questionnaire, and the Nijmegen Questionnaire, along with a sociodemographic form during a single face-to-face session.

05

What researchers measure

Primary outcomes

  1. Fagerström Test for Nicotine Dependence

    his instrument will assess the severity of nicotine dependence through six items evaluating daily cigarette consumption and smoking patterns.

    Time frame: Measured once during the single face-to-face evaluation session

  2. Nijmegen Questionnaire

    This questionnaire will assess the symptom burden of respiratory, neurovegetative, and neuromuscular features to identify a dysfunctional breathing-compatible symptom pattern.

    Time frame: Measured once during the single face-to-face evaluation session.

  3. International Physical Activity Questionnaire Short Form

    This tool will evaluate the participant's physical activity levels over the previous week by recording the duration and frequency of walking and physical activities.

    Time frame: Measured once during the single face-to-face evaluation session.

06

Study locations

No study locations are listed for this record.

07

Registry details

Key details

Study ID
NCT07843524
Lead sponsor
Istinye University
Responsible party
Yunus Emre Tutuneken (Dr. Assistant Professor, Istinye University) — Principal investigator
First posted
Sep 28, 2026
Start date
Sep 30, 2026 (estimated)
Primary completion
Nov 15, 2026 (estimated)
Completion
Nov 15, 2026 (estimated)
Last update
Sep 28, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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