An interventional study of Standardized Acute Exercise Protocol in Exercise, Physical Performance and Circadian Rhythm, sponsored by Firat University. Completed at 1 site in Turkey (Türkiye). Open to male participants aged 18 Years to 25 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-17.
Sponsored by Firat University · Not applicable, Interventional, and Basic science
Among 10 studies in Motor Activity by Firat University — 4 open to participants now, 4 under way, none of them phase 3. Motor Activity · Firat University.
Among the 10 studies in Motor Activity by Firat University, this one is the only one that started in 2025, is one of 8 with no phase, and was the 10th registered.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
Browse Motor Activity studies →4 of the 10 studies in Motor Activity by Firat University are open now, in 1 country. Recruiting first, the newest first:
Firat University · Sites in Turkey
Ages 18–65
Firat University · Sites in Turkey
Ages 18–65 · Women only
Firat University · Sites in Turkey
Ages 18–65
Firat University · Sites in Turkey
Ages 18–65
By country, each count listing its studies:
Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.
This study: 18 Years to 25 Years · male · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
10 studies; the count open now beside each. This study's row is marked.
First in 2019; this study’s year is marked. 1 started in 2025.
This study's enrollment of 8 is below the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Median enrollment 28 across the 8 interventional studies, 31 across the 2 observational. Of the 3 that completed or were terminated, 0 (0%) have results posted.
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Firat University is the lead sponsor of 117 studies on the registry; 46 are open to participants now.
None of the studies under way reaches primary completion within a year.
Among the 10 studies in Motor Activity by Firat University, from their registry updates:
Nothing recorded among them since 2026-09-25.
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This study aims to investigate whether the time of day at which acute exercise is performed influences physical performance and acute hormonal and biochemical responses in healthy young male soccer players. Participants will complete the same standardized exercise protocol in the morning (08:00-09:30) and evening (17:00-18:30), with a 96-hour interval between sessions. Performance will be assessed using vertical jump and Yo-Yo shuttle run tests. Blood samples will be collected before exercise, immediately after exercise, and two hours after exercise to assess testosterone, cortisol, creatine kinase, AST, ALT, LDH, and troponin levels. The study will examine whether exercise responses differ between morning and evening sessions and whether these differences are consistent with circadian variation.
The purpose of this study is to examine the acute effects of exercise performed at different times of the day on physical performance, hormonal responses, and biochemical markers associated with exercise-induced muscle stress and recovery in healthy young male soccer players.
The study uses a single-group, repeated-measures pre-test/post-test design in which the same participants complete an identical standardized exercise protocol on two separate occasions. One exercise session will be performed in the morning between 08:00 and 09:30, and the other will be performed in the evening between 17:00 and 18:30. The two experimental sessions will be separated by 96 hours (4 days) to reduce the influence of the preceding exercise session on subsequent measurements.
Before each exercise session, participants will undergo anthropometric assessment and provide a resting blood sample. Participants will then complete standardized physical performance assessments, including a vertical jump test and a Yo-Yo shuttle run endurance test. Immediately after completion of the exercise protocol, a second blood sample will be collected. A third blood sample will be collected two hours after exercise to assess the early recovery response.
Blood samples will be analyzed for hormonal and biochemical parameters, including testosterone and cortisol as hormonal markers, and creatine kinase (CK), aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), and troponin as biochemical markers of exercise-related physiological and metabolic responses.
The primary purpose of the comparison is to determine whether the acute physiological responses to the same exercise stimulus differ according to the time of day. The study will also explore the potential relationship between exercise timing and circadian variation in physical performance, hormonal responses, and biochemical markers.
All participants will complete the same exercise and measurement procedures under standardized conditions. The study population consists of healthy male soccer players who regularly participate in sports. Participants must be physically able to safely complete the exercise and assessment protocols and must not have medical or musculoskeletal conditions that could affect exercise performance or the safety of the study procedures.
This study is designed to provide information about the influence of exercise timing on acute performance and physiological responses and may contribute to the development of time-of-day considerations in exercise programming and sports training.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Healthy male soccer players participated in a single-group intervention study. All participants completed the same standardized acute exercise protocol twice, once in the morning (08:00-09:30) and once in the evening (17:00-18:30), separated by 96 hours. Performance tests (vertical jump and Yo-Yo shuttle run) and blood samples were obtained before exercise, immediately after exercise, and 2 hours after exercise to evaluate hormonal and biochemical responses.
Behavioral: Standardized Acute Exercise Protocol
Participants completed a standardized acute exercise protocol consisting of a vertical jump test and a Yo-Yo shuttle run endurance test. The protocol was performed twice, once in the morning (08:00-09:30) and once in the evening (17:00-18:30), with a 96-hour washout period between sessions. Blood samples were collected before exercise, immediately after exercise, and 2 hours after exercise to assess hormonal (testosterone and cortisol) and biochemical (CK, AST, ALT, LDH, and troponin) responses.
Yo-Yo Shuttle Run Performance
Change in endurance performance measured by the Yo-Yo shuttle run test following the standardized acute exercise protocol performed in the morning and evening.
Time frame: Immediately after completion of the exercise performance assessment during each experimental session.
Vertical Jump Performance
Explosive lower-extremity performance will be assessed using the vertical jump test during the morning and evening experimental sessions.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise.
Serum Testosterone Concentration
Serum testosterone concentration will be assessed from blood samples collected before exercise, immediately after exercise, and 2 hours after exercise during the morning and evening experimental sessions.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise.
Serum Cortisol Concentration
Serum cortisol concentration will be assessed from blood samples collected before exercise, immediately after exercise, and 2 hours after exercise during the morning and evening experimental sessions.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise.
Serum Creatine Kinase (CK) Concentration
Serum creatine kinase concentration will be assessed as a biochemical marker of exercise-related physiological response using blood samples collected before exercise, immediately after exercise, and 2 hours after exercise.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise.
Serum Aspartate Aminotransferase (AST) Concentration
Serum AST concentration will be assessed from blood samples collected before exercise, immediately after exercise, and 2 hours after exercise during the morning and evening sessions.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise.
Serum Alanine Aminotransferase (ALT) Concentration
Serum ALT concentration will be assessed from blood samples collected before exercise, immediately after exercise, and 2 hours after exercise during the morning and evening sessions.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise.
Serum Lactate Dehydrogenase (LDH) Concentration
Serum LDH concentration will be assessed from blood samples collected before exercise, immediately after exercise, and 2 hours after exercise during the morning and evening sessions.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise.
Serum Troponin Concentration
Serum troponin concentration will be assessed from blood samples collected before exercise, immediately after exercise, and 2 hours after exercise during the morning and evening experimental sessions.
Time frame: Baseline (pre-exercise), immediately post-exercise, and 2 hours post-exercise
Plan to share: No — Individual participant data will not be made available to other researchers. The study dataset will be used for the purposes described in the study protocol and will not be shared at the individual participant level.
No publications or documents are linked to this record.
Ran from Nov 2025 to primary completion in Dec 2025, 0 months.
Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 0 months is below that.
Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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