An interventional study of Pilates Exercise and Walking Exercise in Elevated Blood Pressure, sponsored by Universidade Estadual do Norte do Parana. Completed at 1 site in Brazil. Open to female participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-09-14.
Sponsored by Universidade Estadual do Norte do Parana · Not applicable, Interventional, and Treatment
Among 208 studies in Hypertension with a site in Brazil — 30 open to participants now, 34 under way, 6 of them phase 3. Hypertension · Brazil.
Among the 208 studies in Hypertension with a site in Brazil, this one is the 182nd largest by enrollment of the 189 interventional ones that give a count, is one of 12 that started in 2024, is one of 112 with no phase, and was the 207th registered.
6,114 studies on the registry are indexed under Hypertension; 912 are open to participants now.
Browse Hypertension studies →30 of the 208 studies in Hypertension with a site in Brazil are open now. Recruiting first, the newest first:
University of Nove de Julho · Sites in Brazil
Ages 18–65
AstraZeneca · Sites in Brazil
Ages 18+
Instituto Dante Pazzanese de Cardiologia · Sites in Brazil
Ages 18+
Raphael Mendes Ritti Dias · Sites in Brazil
Ages 60+
Universidade Federal Fluminense · Sites in Brazil
Ages 18–75
A study can be open while its sites in Brazil have not opened yet or have stopped. Only those recruiting at a site in Brazil →
Of the 564 Hypertension studies recruiting now, 266 (47%) set no upper age limit and 200 (35%) stop at 75 or younger; 40 take children under 18; 138 take healthy volunteers.
This study: 50 Years and older · female · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
208 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 3 · Phase 2 7 · Phase 3 40 · Phase 4 31
First in 1999; this study’s year is marked. 12 started in 2024.
By drug class, each counting the studies that test any of its medicines:
This study's enrollment of 15 is below the median of 100 across 4,575 interventional studies indexed under Hypertension.
Median enrollment 80 across the 189 interventional studies, 124 across the 17 observational. Of the 134 that completed or were terminated, 20 (15%) have results posted.
This tab as a report to print or save as PDF → With an account.
37 of 208 have an industry lead sponsor. The 10 most frequent:
Universidade Estadual do Norte do Parana is the lead sponsor of 12 studies on the registry; 2 are open to participants now.
Universidade Estadual do Norte do Parana has 1 study filed under Hypertension — fewer than ten, so there is no comparison to draw.
19 of the studies in Hypertension with a site in Brazil that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT03683186Phase 3United TherapeuticsA Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension | 2026-12 |
| NCT07361276AstraZenecaObservational Study That Will Evaluate Treatment Patterns in the Management of Hypertension in the Public Primary Care System | 2026-11-30 |
| NCT07058922National Institute of Cardiology, Laranjeiras, BrazilAcute Effects of Powdered Beetroot Extract Supplementation on the Microcirculation of Resistant Hypertensive Individuals | 2026-12 |
| NCT06105775University of Sao PauloInorganic Nitrate Supplementation in Chronic Hypertensive Pregnancies | 2026-12 |
| NCT06169241National Institute of Cardiology, Laranjeiras, BrazilEffect of Nitrate Supplementation on Blood Pressure and Microvascular Function of Resistant Hypertensive Patients | 2026-12 |
Among the 208 studies in Hypertension with a site in Brazil, from their registry updates:
This tab as a report to print or save as PDF → With an account.
The objective of this randomized crossover clinical trial was to evaluate the acute effect of a Pilates exercise session on blood pressure in women aged 50 years or older. The main questions investigated were:
In the Pilates condition, participants performed a session lasting approximately 50 minutes, consisting of 10 exercises. In the walking condition, they performed approximately 50 minutes of treadmill walking at an intensity corresponding to 60-70% of their maximum heart rate. After each experimental condition, blood pressure was monitored for 24 hours using ABPM.
This randomized crossover clinical trial investigated the acute effect of a single Pilates exercise session on ambulatory blood pressure in women aged 50 years or older with elevated blood pressure.
The study was conducted through three experimental sessions. In the first session, all participants underwent the control/baseline condition, which included clinical and sociodemographic assessment, familiarization with the assessment procedures, and baseline blood pressure measurements. An ambulatory blood pressure monitoring device was then fitted and maintained for 24 hours without exercise, establishing the control condition.
Following the control/baseline session, participants were randomly assigned to one of two intervention sequences: Pilates followed by walking or walking followed by Pilates. A six-day interval was maintained between the experimental sessions. Thus, all participants completed both exercise interventions, but the order of the interventions was randomized.
The walking session was performed on a treadmill for 50 minutes at an individually prescribed intensity of 60-70% of heart rate reserve. Heart rate was continuously monitored throughout the session, and treadmill speed was adjusted as necessary to maintain the target intensity.
The Pilates session was performed on a mat using body weight and a Magic Circle accessory. The session lasted 50 minutes and consisted of 10 exercises involving the trunk, upper limbs, and lower limbs. Each exercise was performed for one set of 10 repetitions, with a one-minute interval between exercises. Participants were previously instructed and familiarized with the correct execution of the exercises.
After each exercise session, ambulatory blood pressure was monitored for 24 hours. Monitoring began at 2:00 PM and included measurements during both waking and sleeping periods. Participants maintained their usual medication regimen throughout the study and recorded relevant daily information, including medication use, meals, sleep and wake times, and stressful events, in an activity diary.
Heart rate, perceived exertion, satisfaction, and affective responses were also assessed during the exercise sessions to characterize the physiological and subjective responses to the two exercise modalities.
The study was conducted in accordance with ethical principles for research involving human participants and received approval from the Research Ethics Committee under opinion number 4.170.827. All participants provided informed consent before participation.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants first completed a 50-minute Pilates exercise session. The session consisted of 10 exercises performed on a mat using body weight and a Metalife Magic Circle, with one set of 10 repetitions for each exercise and a 1-minute interval between exercises. After a 6-day washout period, participants completed a 50-minute walking session on a treadmill at 60-70% of heart rate reserve. Ambulatory blood pressure monitoring was performed for 24 hours after each exercise session.
Behavioral: Pilates Exercise · Behavioral: Walking Exercise
Participants first completed a 50-minute walking session on a treadmill at 60-70% of heart rate reserve. After a 6-day washout period, participants completed a 50-minute Pilates exercise session. The Pilates session consisted of 10 exercises performed on a mat using body weight and a Metalife Magic Circle, with one set of 10 repetitions for each exercise and a 1-minute interval between exercises. Ambulatory blood pressure monitoring was performed for 24 hours after each exercise session.
Behavioral: Pilates Exercise · Behavioral: Walking Exercise
A single 50-minute Pilates exercise session was performed on a mat using body weight and a Metalife Magic Circle. The session consisted of 10 exercises, with one set of 10 repetitions for each exercise and a 1-minute interval between exercises. The exercises targeted mobility, flexibility, strengthening, and trunk and lower- and upper-limb movements. Participants were previously familiarized with the exercises and instructed on their proper execution.
A single 50-minute walking session was performed on a treadmill. Exercise intensity was individually prescribed at 60-70% of heart rate reserve, with continuous heart rate monitoring throughout the session. Treadmill speed was progressively adjusted as needed to maintain the target heart rate range.
24-hour ambulatory blood pressure
Twenty-four-hour ambulatory blood pressure was assessed after each experimental condition using ambulatory blood pressure monitoring. Systolic and diastolic blood pressure were recorded throughout the 24-hour monitoring period, including waking and sleeping periods, to evaluate the acute effects of Pilates and walking on blood pressure.
Time frame: 24 hours after each experimental condition
Systolic Blood Pressure
Systolic blood pressure was assessed using 24-hour ambulatory blood pressure monitoring after each condition. Mean values were evaluated for the total 24-hour period and separately for waking and sleeping periods to compare the acute responses to Pilates, treadmill walking, and the control condition.
Time frame: 24 hours after each condition
Diastolic Blood Pressure
Diastolic blood pressure was assessed using 24-hour ambulatory blood pressure monitoring after each condition. Mean values were evaluated for the total 24-hour period and separately for waking and sleeping periods to compare the acute responses to Pilates, treadmill walking, and the control condition.
Time frame: 24 hours after each condition
Mean Arterial Pressure
Mean arterial pressure was assessed using 24-hour ambulatory blood pressure monitoring after each condition. Mean values were evaluated for the total 24-hour period and separately for waking and sleeping periods to compare the acute responses to Pilates, treadmill walking, and the control condition.
Time frame: 24 hours after each condition
Pulse Pressure
Pulse pressure was assessed using 24-hour ambulatory blood pressure monitoring after each condition. Mean values were evaluated for the total 24-hour period and separately for waking and sleeping periods to compare the acute responses to Pilates, treadmill walking, and the control condition.
Time frame: 24 hours after each condition
Affective Valence
Affective response was assessed during each exercise session using an 11-point bipolar Affective Valence Scale ranging from -5 (very bad) to +5 (very good), with 0 representing a neutral state. The scale was administered at 10 time points during each exercise session.
Time frame: During each 50-minute exercise session
Plan to share: No
No publications or documents are linked to this record.
Ran from Aug 2024 to primary completion in Dec 2024, 4 months.
Of 1,403 non-industry interventional studies with no phase under Hypertension, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 41. This study's 4 months is below that.
Counting every sponsor, half of 1,498 studies reached it within 23 months; a quarter within 10 and three quarters within 41.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Universidade Estadual do Norte do Parana