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Not yet recruitingNCT07817992Updated Sep 14, 2026

Effect of Virtual Reality- Based Training on Cervical Mobility, Proprioceptive Accuracy and Hand Grip Strength in Patients With Cervical Radiculopathy

An interventional study of Virtual reality training using Shinecon Virtual Reality 3D Glasses and Conventional physical therapy program in Cervical Radiculopathy, sponsored by Cairo University. Not yet recruiting. Open to participants aged 35 Years to 50 Years. Per ClinicalTrials.gov, last updated 2026-09-14.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
35 Years to 50 Years
Sex
All
01

Study summary

The aim of this study is to investigate the effect of virtual reality training on cervical mobility, proprioceptive accuracy and hand strength in patients with cervical radiculopathy. Forty patients of both sexes diagnosed with cervical radiculopathy will participate in this study. The participants' ages will be varied from 35 to 50 years, with a body mass index less than 30 kg/m². Patients will be randomly allocated to virtual reality and control groups. Both groups will receive a conventional physical therapy program in the form of electrotherapy, manual therapy, and strengthening exercises. The virtual reality group will receive virtual reality training in addition to the same physical therapy program. All participants will be assessed before and after treatment using the Joint Position Error by laser pointer for proprioceptive accuracy assessment; cervical ROM (CROM) for cervical mobility assessment; and hand dynamometer for hand grip strength. The treatment will be conducted three sessions per week for six weeks.

02

Conditions studied

  • Cervical Radiculopathy

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Keywords

  • cervical radiculopathy
  • Virtual reality training
  • Propioception
  • Cervical mobility
  • Hand strength
03

In context

Radiculopathy

483 studies on the registry are indexed under Radiculopathy; 145 are open to participants now.

This study's planned enrollment of 40 is below the median of 60 across 373 interventional studies indexed under Radiculopathy.

Browse Radiculopathy studies →

Lead sponsor

Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Patients with unilateral cervical radiculopathy Patients aged 35 to 50 years. Both sexes The patient has experienced chronic neck pain for over six months. Neck pain intensity of 3 to 8 score by Visual Analog Scale. Positive findings in at least 3 out of 4 clinical assessments: Spurling's test, distraction test, upper limb tension test, and ipsilateral cervical rotation \< 60 degrees.

less than 30 kg/m².

Exclusion criteria

Exclusion Criteria:

  • Disorders of the temporomandibular joint.

    • Primary issues related to the shoulder or upper limb.
    • Neurological deficits, cognitive impairments (MOCA\< 25), or a history of cervical spine surgery.
    • Neck discomfort accompanied by dizziness or referred pain in both upper limbs.
    • Clinical instability, recent trauma, or vertebrobasilar insufficiency.
    • Structural irregularities of the spine (e.g., osteoporosis, ankylosing spondylitis, or rheumatoid arthritis).

Pregnant females

Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    Virtual Reality group

    Participants will receive 30 minutes of conventional physical therapy program in addition to 30 minutes of Virtual reality-based Training. The conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises. Virtual reality-based Training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality 3D glasses for 30 minutes per session, three sessions per week for 6 weeks.

    Other: Virtual reality training using Shinecon Virtual Reality 3D Glasses · Other: Conventional physical therapy program

  • Active comparator
    Control group

    Participants will receive 60 minutes of conventional physical therapy program. It will be the same as virtual reality group ( Transcutaneous Electrical Nerve Stimulation (TENS), Ultrasound Therapy, Manual Therapy and Strengthening Exercises).

    Other: Conventional physical therapy program

Interventions

  • OtherVirtual reality training using Shinecon Virtual Reality 3D Glasses

    The virtual reality training will be in the form of virtual activities including postural correction via chin in exercise from sitting, supine and prone positions; and strengthening exercises using virtual reality for 30 minutes per session, three sessions per week for 6 weeks.

  • OtherConventional physical therapy program

    The conventional physical therapy program will be in the form of Transcutaneous Electrical Nerve Stimulation (TENS) (frequency of 50-100 Hz, a pulse duration between 50-200 µs, and an intensity adjusted to a comfortable, non-painful level), Ultrasound Therapy (frequency of 1 MHz, intensity of 0.5-1.0 W/cm², and a 50% duty cycle for pulsed ultrasound)., Manual Therapy ( Grade III and IV Cervical Mobilization, soft Tissue Manipulation in the form of Deep tissue massage and myofascial release techniques for the cervical and upper trapezius muscles, and Strengthening Exercises for cervical and upper limb muscles).

06

What researchers measure

Primary outcomes

  1. Active cervical ROM (CROM)

    Cervical mobility will be assessed using an objective CROM goniometer. First, the patients will be asked to assume an upright sitting with the head in the neutral position. The CROM device will be placed firmly on the head and the the Velcro strap will be secured tightly and then calibrated. The sagittal, frontal, and horizontal gravity meters will be set to 0°. Then, each patient will be asked to perform active cervical ROM in the three planes as the following: flexion, extension, right and left rotation, and right and left side bending. The patients will be stabilized during all ROM assessments to prevent substitutions. All six ROMs will be recorded as degrees.

    Time frame: From enrollment to the end of treatment at 6 weeks

Secondary outcomes

  1. Joint Position Error for proprioceptive accuracy assessment

    A laser pointer will be used for proprioception assessment through Joint Position Error (JPE). It will be placed on the patient's forehead. A2-sized chart with a reference point in the center will be positioned 90cm in front of patient. The patient will sit down 90 cm from the wall, and the reference point of the laser projection will be marked. All patients will be blindfolded and asked to move the head actively away from the reference position to full range and then attempt to reposition the head back to the reference point as accurately as possible. The patients will perform one familiarization trial with eyes open. Head movement will be in the form of cervical flexion, extension, right rotation, and left rotation. Each head movement will be repeated for six times. The JPE will be measured as the difference between the reference position and the returning point in the plane of movement in centimeters and will be converted to degrees. The average of the 6 trials will be used.

    Time frame: From enrollment to the end of treatment at 6 weeks

  2. Hand grip strength

    Hand grip strength will be assessed by Electronic Hand Dynamometer. The participants will be asked to assume an upright sitting position with their forearm in neutral position and rested on the chair, shoulder in 30° abduction, elbow in 90° and wrist in neutral position. Each patient will perform three trials of maximal isometric contraction of hand muscles by applying as much pressure as possible on the dynamometer for at least six seconds. The highest maximal isometric hand strength will be recorded as in Kilogram (Kg).

    Time frame: From enrollment to the end of treatment at 6 weeks

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 14, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07817992
Lead sponsor
Cairo University
Responsible party
Marwa Mostafa Abdel Moneim Afifi (Lecturer at Physical therapy for Neurology Department, Faculty of Physical Therapy, Cairo University, Cairo University) — Principal investigator
First posted
Sep 14, 2026
Start date
Dec 1, 2026 (estimated)
Primary completion
Jul 1, 2027 (estimated)
Completion
Jul 20, 2027 (estimated)
Last update
Sep 14, 2026

Study contacts

Marwa Mostafa
Contact
marwamostsfa506@gmail.com
00201005661591

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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