An interventional study of standard Holmium laser enucleation of the prostate and Virtual basket Holmium laser enucleation of the prostate in BPH/LUTS/Sexual Functions, sponsored by Mansoura University. Completed at 1 site in Egypt. Open to male participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2026-09-11.
Sponsored by Mansoura University · Not applicable, Interventional, and Treatment
We aimed to assess impart of VB-HoLEP in management of BPH
The aim of this study is to evaluate safety and efficacy of pulse modulated HoLEP compared to Standard HoLEP as regard sexual and urinary outcomes
LUTS secondary to BOO due to BPH with indication for surgical intervention:
International prostate symptom scores (IPSS) >15 and bother score (QOL) ≥ 3 (according to IPSS question 8) Peak urinary flow rate (Qmax) \<15 ml/sec with at least 150 ml voided volume or catheterized patients due to acute urine retention secondary to BPH who failed trial of voiding on medical treatment.
ASA (American society of anesthesiologists) score ≤3. Prostate size as measured by TRUS ≥80 cc.
Exclusion Criteria:
Patient with neurological disorder which might affect bladder function as cerebrovascular stroke, Parkinson disease Active urinary tract infection (till treated by culture-based antibiotics) Presence of active bladder cancer. Known prostate cancer patients will be excluded preoperatively based on digital rectal examination, prostate specific antigen level, and TRUS imaging followed by prostate biopsies if necessary.
Patient has had an acute myocardial infarction or open-heart surgery \<180 days prior to the date of informed consent.
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standard holmium laser enucleation of the prostate for large sized prostate
Procedure: standard Holmium laser enucleation of the prostate
Virtual basket holmium laser enucleation of the prostate for large sized prostate
Procedure: Virtual basket Holmium laser enucleation of the prostate
prostate enucleation using holmium laser with laser settings 2J/50Hz
prostate enucleation using holmium laser with laser settings adjust to virtual basket mode
Enucleation effeciency
calculated by dividing the overall resected prosatate volume by the enucleation time in gm/min.
Time frame: 6 months
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Plan to share: No
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Mansoura University