An interventional study of Extra-Virgin Olive Oil in Lung Cancer and Chylothorax, sponsored by Fudan University. Recruiting at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-09-08.
Sponsored by Fudan University · Not applicable, Interventional, and Prevention
Among 15 studies in Lung Neoplasms by Fudan University — 9 open to participants now, 9 under way, 4 of them phase 3. Lung Neoplasms · Fudan University.
Among the 15 studies in Lung Neoplasms by Fudan University, this one has the largest planned enrollment of the 10 interventional ones, is one of 4 that started in 2026, is one of 2 with no phase, and was the 15th registered.
5,422 studies on the registry are indexed under Lung Neoplasms; 1,346 are open to participants now.
This study's planned enrollment of 1,036 is above the median of 60 across 3,656 interventional studies indexed under Lung Neoplasms.
Browse Lung Neoplasms studies →9 of the 15 studies in Lung Neoplasms by Fudan University are open now, in 1 country. Each count lists the studies.
Of the 996 Lung Neoplasms studies recruiting now, 683 (69%) set no upper age limit and 142 (14%) stop at 75 or younger; 45 take children under 18; 142 take healthy volunteers.
This study: 18 Years to 80 Years · all sexes · no healthy volunteers.
The full table on the hub →15 studies; the count open now beside each. This study's row is marked.
First in 2013; this study’s year is marked. 4 started in 2026.
Median enrollment 256 across the 10 interventional studies, 876 across the 5 observational. Of the 3 that completed or were terminated, 0 (0%) have results posted.
Fudan University is the lead sponsor of 1,315 studies on the registry; 643 are open to participants now.
3 of the studies in Lung Neoplasms by Fudan University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06547710Fudan UniversityPrimary Tumor Resection for M1a Stage Lung Cancer | 2026-12 |
| NCT07626177Fudan UniversityAssociation Between Screening Behaviors and Lung Cancer Spectrum | 2027-05-01 |
| NCT07807696Fudan UniversityOlive Oil Before Lung Cancer Surgery to Prevent Chylothorax | 2027-06-01 |
Among the 15 studies in Lung Neoplasms by Fudan University, from their registry updates:
Nothing recorded among them since 2026-09-25.
Chylothorax is a rare but serious complication after lung cancer surgery and mediastinal lymph node dissection. This multicenter randomized trial will evaluate whether drinking 40 mL of extra-virgin olive oil 4 hours before surgery can reduce the occurrence of chylothorax after curative lung cancer resection. A total of 1,036 adults with resectable lung cancer will be assigned in a 1:1 ratio to preoperative oral olive oil or standard preoperative fasting without additional olive oil. The primary outcome is the occurrence of chylothorax within 30 days after surgery. Secondary outcomes include repeat surgery, postoperative complications, chest drainage, length of chest tube use, length of hospital stay, and the safety and tolerability of the intervention.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
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Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
ECOG performance status
A scale of how much an illness limits everyday activity. For people being assessed to join a study, scores run from 0 (fully active) to 4; lower is more active.
Studies most often ask for 0–1 or 0–2. Your doctor gives the score; the WHO scale uses the same steps. The full scale also has 5, which records death.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants drink 40 mL of extra-virgin olive oil 4 hours before surgery and then continue fasting from food and water until surgery.
Dietary Supplement: Extra-Virgin Olive Oil
Participants follow each center's standard preoperative fasting regimen: no food for 8 hours and no water for 2 hours before surgery. No additional olive oil is given.
A single 40 mL dose of extra-virgin olive oil is taken orally 4 hours before curative lung cancer surgery. After ingestion, participants continue fasting from food and water until surgery.
Incidence of Postoperative Chylothorax
Percentage of participants diagnosed with postoperative chylothorax. Chylothorax is defined as pleural drainage fluid triglycerides greater than 110 mg/dL (1.2 mmol/L) or a typical milky appearance of pleural drainage after resumption of oral dietary fat.
Time frame: Within 30 days after surgery
Incidence of Postoperative Complications
Percentage of participants with one or more surgery-related postoperative complications, including prolonged air leak, atrial fibrillation or other arrhythmia, postoperative bleeding, pulmonary infection, respiratory insufficiency, bronchopleural fistula, pneumothorax or atelectasis, recurrent laryngeal nerve injury, or death.
Time frame: Within 30 days after surgery
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