An interventional study of formulation of green tea leaf extract, bamboo shoot extract and selenium-enriched yeast and formulation of grape seed extract, bamboo shoot extract and selenium-enriched yeast in Androgenic Alopecia and Healthy Adult Male, sponsored by Activ'inside. Recruiting at 6 sites in Italy. Open to male participants aged 35 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-11-09.
Sponsored by Activ'inside · Not applicable, Interventional, and Treatment
The goal of this clinical trial is to evaluate the efficacy and safety of two different formulations of a food supplement on hair health in healthy Caucasian male subjects aged 35 to 65 years with mild to moderate androgenetic alopecia. The main questions it aims to answer are:
Researchers will compare two active supplement groups and a placebo group to determine whether the active products improve objective hair parameters and perceived hair quality.
Participants will:
511 studies on the registry are indexed under Alopecia; 128 are open to participants now.
This study's planned enrollment of 99 is above the median of 50 across 430 interventional studies indexed under Alopecia.
Browse Alopecia studies →Activ'inside is the lead sponsor of 8 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Subjects informed about the test procedures who have signed a consent form and privacy agreement
Exclusion Criteria:
Subjects with eating disorders (i.e. bulimia, psychogenic eating disorders, etc.)
Including oncological diseases, diabetes, diseases, acute inflammatory diseases, ongoing infectious diseases, and alopecia areata.
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A planned gap after a treatment, so that its effects can lessen before the study treatment or a study assessment. Ask the study team and the doctor who prescribed it before changing any medicine.
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Washout period
A planned gap after a treatment, so that its effects can lessen before the study treatment or a study assessment. Ask the study team and the doctor who prescribed it before changing any medicine.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Autoimmune disease
A condition in which the immune system attacks the body’s own tissues, such as rheumatoid arthritis, lupus, psoriasis, type 1 diabetes or inflammatory bowel disease.
Immunotherapy studies often leave out active autoimmune disease, and some name exceptions, such as thyroid disease on replacement hormone. Check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
hard shell capsule containing green tea leaf extract (Camellia sinensis (L.) Kuntze, Theaceae), bamboo shoot extract (Bambusa vulgaris Schrad., Poaceae), and selenium-enriched yeast (Saccharomyces cerevisiae) and maltodextrin
Dietary Supplement: formulation of green tea leaf extract, bamboo shoot extract and selenium-enriched yeast
hard shell capsule containing grape seed extract (Vitis vinifera L., Vitaceae), bamboo shoot extract (Bambusa vulgaris Schrad., Poaceae), and selenium-enriched yeast (Saccharomyces cerevisiae) and maltodextrin
Dietary Supplement: formulation of grape seed extract, bamboo shoot extract and selenium-enriched yeast
hard shell capsule containing maltodextrin
Dietary Supplement: Placebo (maltodextrin)
one capsule per day during breakfast with water for 84 days
one capsule per day during breakfast with water for 84 days
one capsule per day during breakfast with water for 84 days
Change in anagen hair density
Number of hairs in anagen phase per cm² and proportion (in %) using phototricogram (TrichoScan)
Time frame: 42 and 84 days
Total number of hair in anagen phase
= (Anagen hair after supplement use x scalp surface) - (Anagen hair before supplement use x scalp surface) where the scalp surface is 580 cm2.
Time frame: 42 and 84 days
Change in telogene hair density
Number of hairs in telogen phase per cm² and proportion (in %) using phototricogram (TrichoScan)
Time frame: 42 and 84 days
Number of hair protected against falling out (HPF)
(TEAF x SH) - (TEBE x SH) where: TEAF is the number of telogen hair after supplement use ; TEBE is the number of telogen hair before product use; SH is the head surface (580cm2).
Time frame: 42 ans 84 days
Change in total hair density
Number of total hairs per cm² using phototricogram (TrichoScan)
Time frame: 42 and 84 days
Change in hair brightness
Hair brightness is measured on 5 points near the hairline using a spectrophotometer/colorimeter CM 700D (Konica-Minolta). The measured parameter is the 8° gloss value (average value of the 5 measures).
Time frame: 42 and 84 days
Change in hair colour lightness
Hair color lightness is measured on 5 points near the hairline using a spectrophotometer/colorimeter CM 700D (Konica-Minolta). The measured parameter is the L\* parameter (average value of the 5 measures) indicating the hair color lightness (i.e. lighter or darker hair).
Time frame: 42 and 84 days
Self-assessment questionnaire
Subjects are asked to reply to a self-assessment questionnaire to assess the efficacy perceived and the pleasantness of the product. Responses are provided spontaneously, without external influence.
Time frame: 42 and 84 days
Plan to share: No — confidential data
No publications or documents are linked to this record.
Started Oct 2026 (actual). Primary completion is estimated for Mar 2027, 5 months after the start.
Of 61 industry-sponsored interventional studies with no phase under Alopecia, half reached primary completion within 9 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 20. This study's planned 5 months is below that.
Counting every sponsor, half of 146 studies reached it within 12 months; a quarter within 6 and three quarters within 27.
Since we started tracking on Sep 25, 2026, the dates moved once, on Nov 9, 2026: start Sep 2026 → Oct 2026, primary completion Feb 2027 → Mar 2027 and completion Feb 2027 → Mar 2027.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
Contact study teamGet an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Activ'inside