An interventional study of AI-Supported Rising-Risk Care Navigation in Population Health Management and Patient Navigation, sponsored by Intermountain Health Care, Inc.. Enrolling by invitation at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-04.
Sponsored by Intermountain Health Care, Inc. · Not applicable, Interventional, and Health services research
ASCEND-MA is an embedded, health-services study of at-risk Medicare Advantage members attributed to Intermountain Health in Utah. Participants are quasi-randomized based on their medical-record-number parity to either AI-supported, nurse-reviewed proactive care navigation or usual care. The study will evaluate whether the program changes cumulative payor-paid healthcare spending over 12 months.
An additional ancillary, separately consented consumer-experience sub-study will sample roughly 45 intervention-arm participants for surveys and interviews about the acceptability, burden, and perceived usefulness of the care-navigation workflow.
308 studies on the registry are indexed under Patient Acceptance of Health Care; 53 are open to participants now.
This study's planned enrollment of 9,906 is above the median of 201 across 217 interventional studies indexed under Patient Acceptance of Health Care.
Browse Patient Acceptance of Health Care studies →Intermountain Health Care, Inc. is the lead sponsor of 120 studies on the registry; 15 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 3 (33%) have results posted.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
•.Enrolled in an eligible Medicare Advantage plan and attributed to Intermountain Health in Utah.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants receive routine clinical care plus the AI Supported Rising Risk Care Navigation strategy. The strategy periodically assesses for care opportunities; every candidate nudge undergoes human clinical review before routing or outreach, and no outreach occurs when no clinically appropriate action is identified
Other: AI-Supported Rising-Risk Care Navigation
Participants receive routine clinical care and existing care-management services under standard eligibility and operating rules. The study introduces no AI-supported care-navigation nudges for this arm and withholds no otherwise available care because of assignment
AI-supported proactive care navigation involves the generation of guideline-informed candidate care-navigation actions from protocol-authorized structured data, human-in-the-loop review by a nurse, and then delivery of the approved suggestion through existing care-management or clinical workflows. The nurse may accept, modify, reroute, or reject each candidate before participant outreach or care-team routing. Reassessment is planned approximately every 90 days and may change intervention delivery, but not assigned-group membership.
Cumulative payer-paid health care spending per participant
Mean cumulative payer-paid health care spending (in U.S. dollars) recorded in claims per participant.
Time frame: 1 year
Rate of All-Cause Acute-Care Episodes
Inpatient admissions, emergency department visits, and observation stays will be combined into acute-care episodes, with related encounters counted once.
Time frame: 1 year
Analyses of Condition (Heart Failure, Diabetes, Chronic Obstructive Pulmonary Disease, Chronic Kidney Disease) specific endpoints
Exploratory analyses will assess prespecified condition-specific care-process and utilization measures in heart failure, diabetes, chronic obstructive pulmonary disease, and chronic kidney disease.
Time frame: 1 year
Plan to share: No
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