An interventional study of Vacuum-Assisted Closure (VAC) Therapy and Conventional dressing in Infected Wound and Diabetic Wound, sponsored by Sargodha Medical College. Completed at 1 site in Pakistan. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-09-03.
Sponsored by Sargodha Medical College · Not applicable, Interventional, and Treatment
Among 11 studies in Wound Infection with a site in Pakistan — 1 open to participants now, 1 under way, 1 of them phase 3. Wound Infection · Pakistan.
Among the 11 studies in Wound Infection with a site in Pakistan, this one is the 6th largest by enrollment of the 10 interventional ones that give a count, is one of 3 that started in 2025, is one of 8 with no phase, and was the 11th registered.
270 studies on the registry are indexed under Wound Infection; 33 are open to participants now.
Browse Wound Infection studies →1 of the 11 studies in Wound Infection with a site in Pakistan is open now. Recruiting first, the newest first:
Dow University of Health Sciences · Sites in Pakistan
Ages 18–60
A study can be open while its sites in Pakistan have not opened yet or have stopped. Only those recruiting at a site in Pakistan →
Of the 23 Wound Infection studies recruiting now, 17 (74%) set no upper age limit and 1 (4%) stop at 75 or younger; 2 take children under 18; 2 take healthy volunteers.
This study: 18 Years to 40 Years · all sexes · no healthy volunteers.
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11 studies; the count open now beside each. This study's row is marked.
First in 2019; this study’s year is marked. 3 started in 2025.
This study's enrollment of 90 is below the median of 141 across 228 interventional studies indexed under Wound Infection.
Median enrollment 93 across the 10 interventional studies, 80 across the 1 observational. Of the 10 that completed or were terminated, 0 (0%) have results posted.
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None of the 11 has an industry lead sponsor. The 9 most frequent:
Sargodha Medical College is the lead sponsor of 13 studies on the registry; 5 are open to participants now.
Sargodha Medical College has 1 study filed under Wound Infection — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 11 studies in Wound Infection with a site in Pakistan, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
Wound healing is a complex and dynamic process that includes an immediate sequence of cell migration leading to repair and closure. Delayed wound healing or non-healing of ulcers is a significant health problem, particularly in older adults. Vacuum assisted closure (VAC) is a relatively new technology with applications in a variety of difficult to manage acute and chronic wounds. Literature showed that the outcomes of VAC is a better than other method. Therefore, this study has been planned. This Randomized controlled trial will be done at Department of General Surgery, Dr Faisal Masood Teaching Hospital, Sargodha for 12 months.Sample size of 90 cases; 45 in each groups will be included through Non-probability consecutive sampling and will be randomly divided into 2 equal groups. In group A, VAC will be applied to wound. In group B, conventional dressing will be applied on wound. Wound size after one week will be assessed. If wound will heal completely, then duration for complete healing will be noted. Success will also be noted. All the data will be recorded in proforma.All the data will be analyzed with SPSS version 25. Both groups will be compared by using independent samples t-test for duration of healing, and wound size after a week and chi-square test for success. P-value ≤ 0.05 will be considered as significant. Conclusion and recommendations will be made to obtain better results with high success rate, which will lead to better quality of life and early discharge of patients.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
> Recurrent cases (on medical record)
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will receive vacuum-assisted closure (VAC) therapy for management of infected lower-limb wounds.
Device: Vacuum-Assisted Closure (VAC) Therapy
Participants will receive conventional wound dressing for management of infected lower-limb wounds.
Other: Conventional dressing
Application of vacuum-assisted closure (VAC) therapy to infected lower-limb wounds using negative pressure wound therapy, with appropriate wound preparation and dressing changes according to the study protocol."
Routine conventional dressing of infected lower-limb wounds using standard wound-care techniques and appropriate dressing materials, with dressing changes performed according to the study protocol."
Change in wound size
Time frame: 7 days after initiation of treatment
Treatment success rate
Time frame: Within two weeks of treatment
Duration of treatment/complete healing
Time frame: Treatment success rate within 2 weeks
Plan to share: No
No publications or documents are linked to this record.
Ran from Jul 2025 to primary completion in Aug 2026, 12 months.
Of 59 non-industry interventional studies with no phase under Wound Infection, half reached primary completion within 19 months of starting (the median), counting those still running; a quarter within 13 and three quarters within 53. This study's 12 months is below that.
Counting every sponsor, half of 64 studies reached it within 19 months; a quarter within 13 and three quarters within 53.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.
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Sargodha Medical College