ClinicalTrials.gg
RecruitingNCT07795021Updated Aug 31, 2026

Stroke Care During the COVID-19 Pandemic

An observational study in Stroke (CVA) or TIA, sponsored by Dr. Yaroslav Winter. Recruiting at 4 sites in 4 countries. Per ClinicalTrials.gov, last updated 2026-08-31.

Sponsored by Dr. Yaroslav Winter · Observational

From the registry’s dates

  • Started Jul 2026; still recruiting 4 months later.
Study type
Observational
Model
Other
Time perspective
Retrospective
Enrollment
40,000
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 83 studies in Stroke with a site in Czechia — 12 open to participants now, 20 under way, 3 of them phase 3. Stroke · Czechia.

Planned enrollment
2nd of 22
40,000 · median 350
Started
2026
with 2 others
Observational
22 of 83
8 open now
Primary completion
2026-09
later than 13 of 19 live
Registered
81st of 83
by date

Among the 83 studies in Stroke with a site in Czechia, this one is the 2nd largest by planned enrollment of the 22 observational ones that give a count, is one of 3 that started in 2026, is one of 22 observational ones, reaches primary completion later than 13 of the 19 other live ones, and was the 81st registered.

Stroke

8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.

Browse Stroke studies →

Open to participants now

12 of the 83 studies in Stroke with a site in Czechia are open now. Recruiting first, the newest first:

6 more — sign in →

All 12 open studies →

A study can be open while its sites in Czechia have not opened yet or have stopped. Only those recruiting at a site in Czechia →

Who these studies take

Of the 1,415 Stroke studies recruiting now, 697 (49%) set no upper age limit and 280 (20%) stop at 75 or younger; 77 take children under 18; 196 take healthy volunteers.

This study: all sexes · no healthy volunteers.

The full table on the hub →

This tab as a report to print or save as PDF → With an account.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 83 studies in Stroke with a site in Czechia, or all of them as a file.
02

Study summary

Background: The SARS-CoV-2 pandemic led to substantial changes in the allocation of healthcare resources and affected the behavior of patients experiencing stroke symptoms. Previous studies have mainly focused on the so-called "first wave" of the pandemic during the first half of 2020. During this period, the number of hospital admissions of patients with transient ischemic attacks (TIAs) and minor strokes decreased significantly in many hospitals. This reduction was attributed not only to the reallocation of healthcare resources toward the care of patients with COVID-19, but also to patients' concerns about becoming infected with SARS-CoV-2 during a hospital stay. Since then, the situation has changed, as hospitals have become better prepared to treat patients with COVID-19 and the public has become better informed about the risks of SARS-CoV-2 infection. It is therefore possible that the pattern of acute stroke care during the subsequent wave of COVID-19, which began in autumn 2020, differed from that observed during the first wave.

Aim: The aim of this project is to analyze changes in patterns of acute stroke care across different regions of Europe during the first and subsequent waves of the COVID-19 pandemic and to identify epidemiological determinants associated with changes in stroke care.

Methods: We will collect and analyze data on hospital admissions of patients with acute ischemic stroke, hemorrhagic stroke, and transient ischemic attacks (TIAs) from approximately 40 participating stroke units across Europe for the period from January 1, 2019, to June 30, 2021.

The following parameters will be collected:

Number of hospital admissions per month and mean length of hospital stay (LOS) per month from January 1, 2019, to June 30, 2021, for the following diagnoses:

ischemic stroke hemorrhagic stroke transient ischemic attack Monthly numbers of thrombolysis and thrombectomy procedures during the same period.

Epidemiological parameters: population density, population age, geography of the region, urban/rural region properties, traffic connection to the first European hot spot of Covid-19, number of nursing homes Care characteritics: hospital size, stroke unit capacity.

Statistical analysis: Changes in the number of stroke admissions and length of hospital stay, as well as rates of thrombolysis and thrombectomy, will be analyzed in relation to regional COVID-19 incidence and mortality rates and other epidemiological parameters, including epidemiological connectivity to the first European COVID-19 hotspot.

Expected outcomes: We aim to identify regional patterns of change in acute stroke care during different phases of the COVID-19 pandemic and to determine epidemiological factors associated with these changes.

Read the detailed description

The study is based on hospital statistics of admissions, length of hospital stay and statistics of thrombolysis and thrombectomy procedures. No individual patients' data will be collected.

03

Conditions studied

  • Stroke (CVA) or TIA

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04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

All patients admitted for stroke or TIA to the participating stroke units between January 1, 2019, and June 30, 2021.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

stroke

Exclusion criteria

Exclusion Criteria:

traumatic cause of stroke

Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

TIA (transient ischaemic attack)

A “mini-stroke”: temporary stroke-like symptoms caused by reduced blood flow to part of the brain, spinal cord or eye, without signs of a new stroke on a scan.

Stroke symptoms need emergency care at once, even if they go away.

05

Study design

Observational model
Other
Time perspective
Retrospective
Enrollment
40,000 participants (estimated)
Patient registry
No

Interventions

  • Otherstatistical analysis

    we will colect hospital statistics. No other interventions will take place

06

What researchers measure

Primary outcomes

  1. hospital admissions

    hospital admissions for stroke ot TIA

    Time frame: 2,5 years

07

Study locations

4 of 4 sites recruiting
  • Departement of Neurology 1st Medical Faculty and General Teaching Hospital
    Prague, Czechia
    Recruiting
  • University Hospital Mainz
    Mainz, Germany
    Recruiting
  • UOC Neurologia, ASST Papa Giovanni XXIII
    Bergamo, Italy
    Recruiting
  • University of Barcelona, Comprehensive Stroke Center, Hospital Clinic
    Barcelona, Spain
    Recruiting
08

References and documents

Publications

  • Hbid Y, Stanley K, Wolfe CDA, Bhalla A, James M, Douiri A; SSNAP Collaboration. Stroke care in the United Kingdom before, during, and after the COVID-19 lockdowns: A retrospective nationwide cohort study. PLoS One. 2025 Sep 2;20(9):e0330903. doi: 10.1371/journal.pone.0330903. eCollection 2025. PubMed 40892745 ↗
  • Dengler J, Abdullah B, Kukolja J, Kuhlen R, Hohenstein S, Dengler NF, Bollmann A, Palm F. Frailty in Stroke Care in Germany Between 2016 and 2022-A Retrospective, Hospital-Based Nationwide Cohort Study. NeuroSci. 2025 Sep 8;6(3):88. doi: 10.3390/neurosci6030088. PubMed 40981263 ↗
  • Abe K, Shibata S, Miyawaki A, Kawachi I. Changes in inpatient and outpatient stroke admissions during COVID-19: a difference-in-differences analysis based on claims data from 242 acute care hospitals in Japan. BMJ Public Health. 2025 Sep 29;3(2):e001958. doi: 10.1136/bmjph-2024-001958. eCollection 2025. PubMed 41035766 ↗
  • Reddi P, Mehta A, Hardigan T, Shafizadeh M, Kellner CP, Dangayach NS, Fifi JT, Mocco J, Majidi S. Acute Ischemic Stroke and Endovascular Thrombectomy During COVID-19 Pandemic: A Nationwide Analysis. Neurosurg Pract. 2025 May 23;6(2):e00144. doi: 10.1227/neuprac.0000000000000144. eCollection 2025 Jun. PubMed 41163989 ↗

Individual participant data

Plan to share: No — IPD will not be collected in this study

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jul 2026 (actual). Primary completion is estimated for Sep 2026, 2 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 26, 2026
First posted
Aug 31, 2026
StartActual
Jul 1, 2026
Primary completionEst.
Sep 30, 2026
CompletionEst.
Oct 30, 2026
Last update
Aug 31, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 31, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07795021
Lead sponsor
Dr. Yaroslav Winter
Responsible party
Dr. Yaroslav Winter (Prof. Dr. Yaroslav Winter, Johannes Gutenberg University Mainz) — Sponsor-investigator
First posted
Aug 31, 2026
Start date
Jul 1, 2026
Primary completion
Sep 30, 2026 (estimated)
Completion
Oct 30, 2026 (estimated)
Last update
Aug 31, 2026

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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