An interventional study of Small Fish Powder and Millet Flour in Child Malnutrition, sponsored by Centre for Food and Nutrition Research, Yaounde. Completed at 1 site in Cameroon. Open to participants aged 6 Months to 7 Months, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-31.
Sponsored by Centre for Food and Nutrition Research, Yaounde · Not applicable, Interventional, and Prevention
This randomized controlled trial evaluated the effectiveness of supplementing the diets of infants aged 6-7 months with small fish powder on growth outcomes in the Garoua 1st Health District, Northern Cameroon. A total of 240 infants were enrolled and randomly assigned to receive either small fish powder or a millet flour control for six months. The primary endpoint was growth effectiveness, defined as achieving a height-for-age Z-score ≥ -1.5 after six months. Secondary outcomes included prevention of acute malnutrition, weight gain, mid-upper arm circumference (MUAC) gain, morbidity frequency, and intervention failure rate. Study procedures comprised weekly ration distribution, anthropometric measurements, hemoglobin and malaria testing, and parental nutritional education. Data were analyzed using SPSS and XLSTAT, with statistical significance set at p \< 0.05.
167 studies on the registry are indexed under Child Nutrition Disorders; 36 are open to participants now.
This study's enrollment of 240 is below the median of 402 across 132 interventional studies indexed under Child Nutrition Disorders.
Browse Child Nutrition Disorders studies →Centre for Food and Nutrition Research, Yaounde is the lead sponsor of 3 studies on the registry; none are open to participants now.
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Dietary Supplement: Small Fish Powder · Dietary Supplement: Millet Flour
Dietary Supplement: Small Fish Powder · Dietary Supplement: Millet Flour
Infants aged 6-7 months will receive a daily ration of small fish powder equivalent to \~25 kcal/day, providing approximately 65% of the recommended daily protein intake for children aged 6-24 months. Parents will be instructed on how to incorporate the powder into the child's usual diet. Weekly distribution will occur at the health center, accompanied by monthly nutrition education and biweekly clinical monitoring.
Infants aged 6-7 months will receive a daily ration of millet flour equivalent to \~25 kcal/day, providing approximately 10% of the recommended daily protein intake for children aged 6-24 months. To standardize taste, 3% fish powder will be added. Parents will be instructed on how to incorporate the flour into the child's usual diet. Weekly distribution will occur at the health center, accompanied by monthly nutrition education and biweekly clinical monitoring.
Height-for-Age Z-score
Growth effectiveness, defined as the proportion of children achieving a height-for-age Z-score ≥ -1.5 SD after six months of supplementation.
Time frame: 6 months
Weight-for-Height Z-score
Prevention of acute malnutrition, defined as weight-for-height Z-score ≥ -1.5 SD.
Time frame: 6 months
Weight Gain
Mean change in body weight (kg) from baseline to six months.
Time frame: 6 months
Mid-Upper Arm Circumference (MUAC) Gain
Mean change in MUAC (cm) from baseline to six months.
Time frame: 6 months
Morbidity Frequency
Number of morbidity episodes (e.g., diarrhea, respiratory infections, malaria) recorded per child during the six-month intervention period.
Time frame: 6 months
Intervention Failure Rate
Proportion of children failing to achieve growth effectiveness (height-for-age Z-score \< -1.5 SD) after six months.
Time frame: 6 months
Hemoglobin Concentration
Mean change in hemoglobin levels (g/dL) from baseline to six months.
Time frame: 6 months
Malaria Prevalence
Proportion of children testing positive for malaria by rapid diagnostic test (RDT) during follow-up.
Time frame: 6 months
Plan to share: Yes — Baseline Characteristics: Infant age, sex, household sociodemographic data, maternal education, household food security and dietary diversity scores. Anthropometric Data: Weight, height/length, mid upper arm circumference (MUAC), Derived indices (height for age, weight for age, weight for height Z scores). Clinical and Laboratory Data: Hemoglobin concentration, Malaria test results, Morbidity episodes (diarrhea, respiratory infections, fever, malaria). Dietary Intake Data: 24 hour dietary recall, Weekly food frequency data, Product consumption records (amount of small fish powder or millet flour consumed, adherence, unused product returned). Follow up Data: Longitudinal measurements at enrollment, 2 months, 4 months, and 6 months, Survival analysis endpoints (growth recovery vs. non recovery).
No publications or documents are linked to this record.
Ran from Jul 2024 to primary completion in Feb 2025, 7 months.
Of 81 non-industry interventional studies with no phase under Child Nutrition Disorders, half reached primary completion within 19 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 36. This study's 7 months is below that.
Counting every sponsor, half of 84 studies reached it within 19 months; a quarter within 11 and three quarters within 40.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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Centre for Food and Nutrition Research, Yaounde