An interventional study of Technology-Supported Hand Training and Pamphlet-Supported Hand Activity in Stroke, sponsored by University of Michigan. Recruiting at 1 site in United States. Open to participants aged 40 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-10-15.
Sponsored by University of Michigan · Not applicable, Interventional, and Treatment
This pilot randomized controlled trial will evaluate the feasibility and preliminary effects of a home-based, technology-enabled hand telerehabilitation program for adults with chronic stroke. Participants will receive either remotely guided hand training or a standard home exercise program matched for duration and intensity. Outcomes will include measures of hand function, adherence, and feasibility to assess the potential of telerehabilitation for improving access to structured post-stroke hand rehabilitation.
Persistent hand impairment after stroke is common and can substantially limit independence in daily activities. Access to intensive, task-specific hand therapy is often constrained by travel, cost, and availability of rehabilitation services, leading many individuals to rely on unsupervised home exercise programs. Telerehabilitation supported by low-cost technology may improve access to structured hand training while allowing remote supervision, but its feasibility and implementation in the home setting require systematic evaluation. This study aims to evaluate the feasibility and preliminary effects of a hand telerehabilitation program for individuals with chronic stroke. The study will be conducted as a single-center pilot randomized controlled trial comparing two home-based interventions: (i) telerehabilitation and (ii) a standard home-advice exercise program matched for duration and intensity. Participants randomized to the telerehabilitation group will complete supervised home training sessions using technology-assisted activities to target hand function, delivered remotely via video conferencing. Participants in the control group will follow a home exercise plan similar to that used in typical post-stroke therapy. Outcome measures will be collected before and after the intervention and will include standardized assessments of hand function, as well as measures of adherence and feasibility. This study (i) involves adult stroke survivors, (ii) presents minimal risk, (iii) does not involve deception, (iv) does not collect sensitive health information, and (v) includes brief, noninvasive, and nonpainful interactions consistent with standard rehabilitation activities.
8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.
This study's planned enrollment of 22 is below the median of 49 across 6,024 interventional studies indexed under Stroke.
Browse Stroke studies →University of Michigan is the lead sponsor of 1,506 studies on the registry; 192 are open to participants now.
Of its 169 completed or terminated interventional studies of FDA-regulated products, 133 (79%) have results posted.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Exclusion Criteria for subjects exposed to Transcranial Magnetic Stimulation (TMS):
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants will undergo a remotely delivered, technology-supported hand training program that involves guided hand activities in 18 sessions over 6 weeks
Behavioral: Technology-Supported Hand Training
Participants will undergo home therapy intervention guided by an advice plan created using typical occupational therapy guidance that includes 18 sessions over 6 weeks
Behavioral: Pamphlet-Supported Hand Activity
Participants will undergo a remotely delivered, technology-supported hand training program that involves guided hand activities. These activities will target finger coordination, finger individuation, and performance in activities of daily living. Participants may interact with virtual or real passive items to supplement program activities. Activities will be guided remotely by a study team member using video conferencing.
Participants will follow a home advice plan to improve hand function. The plan will be created based on the participant's ability and typical occupational therapy guidance. Activities may resemble typical hand rehabilitation activities performed in a therapy clinic and may involve passive items to supplement program activities. Participants will record their adherence to the program.
Hand Spread
Change in voluntary ability to open the more-impaired hand from before the intervention (pre-intervention) to after the intervention (post-intervention). Hand spread will be measured with motion capture equipment. Hand Spread values range from 0 to no upper limit, with a greater value indicating improved voluntary hand opening ability
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Box and Block Test Score
Change in a measure of arm ability from before the intervention (pre-intervention) to after its completion (post-intervention) using publicly available scoring sheets. The Box and Block test is scored based on how many blocks a patient can move between two adjacent boxes in 1 minute with their more-impaired hand. Box and Block scores range from 0 to no upper limit, with a higher score indicating greater arm ability
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Stroke Impact Scale-Hand Score
Change in the hand function component of the Stroke Impact Scale, a participant-reported measure of hand participation in daily life from before the intervention (pre-intervention) to after its completion using publicly available scoring sheets. Stroke Impact Scale-Hand Scores can range from 0 to 100, with a higher score indicating better self-reported hand function in daily life.
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Adherence
Measure of percentage of sessions completed
Time frame: Post-intervention (immediately following last session of intervention)
Qualitative Survey
Subjective feedback regarding feasibility, acceptance, and perceived functional benefits of the intervention. The qualitative survey has no scale.
Time frame: Post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Upper extremity Fugl-Meyer Score (Hand Section) Score
Change in the score on the Hand subsection of the Fugl-Meyer Assessment of Motor Recovery After Stroke - Upper Extremity from pre-intervention to post-intervention. The Hand subsection measures motor impairment of the hand and ranges from 0 to 14 points, with higher scores indicating better motor function.
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Principal Component Ratio
Change in coordination of the finger joints as measured with motion capture from before the intervention (pre-intervention) to after its completion (post-intervention). The ratio of the variance explained by the non-primary coordination patterns to the primary pattern during a free exploration task will be used to compute the Principal Component Ratio. The principal component ratio can vary from 0 to no upper limit, with a higher ratio indicates improved coordination.
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Action Research Arm Test Score
Change in the Action Research Arm Test Score from before the intervention (pre-intervention) to after its completion (post-intervention) using publicly available scoring sheets. The Action Research Arm Test is a measure of arm functional ability and runs from 0 to 57 points, with higher numbers reflecting better functional ability of the arm.
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Nine-Hole Peg Test Score
Change in the Nine-hole peg test score from before the intervention (pre-intervention) to after its completion (post-intervention) using publicly available scoring sheets. The Nine-hole peg test is a measure of arm functional ability quantified by the time required to place and remove nine pegs. Times of the test can vary from 0 to no upper limit with a smaller time reflecting better functional ability of the arm.
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Corticospinal Excitability
Change in corticospinal excitability of the upper extremity muscles as measured using surface electromyography and transcranial magnetic stimulation between before the intervention (pre-intervention) to after its completion (post-intervention).
Time frame: Pre-intervention (an average of up to 1 week before the first intervention session) and post-intervention (an average of up to 1 week after completion of the 6-week intervention)
Plan to share: No
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From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
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