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CompletedNCT07785570Updated Aug 25, 2026

Hamstring Versus Quadriceps Tendon Graft for MPFL Reconstruction

An observational study in Recurrent Patellar Dislocation, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged 18 Years to 40 Years. Per ClinicalTrials.gov, last updated 2026-08-25.

Sponsored by Cairo University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
38
Ages
18 Years to 40 Years
Sex
All
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Study summary

This prospective comparative study compared the clinical and radiological outcomes of medial patellofemoral ligament (MPFL) reconstruction using a hamstring tendon graft versus a quadriceps tendon graft in patients with recurrent patellar dislocation. The study included 38 patients with 40 affected knees who underwent MPFL reconstruction using either a hamstring tendon graft or a quadriceps tendon graft, according to the treating surgeon's preference. Patients were prospectively followed in two groups according to the graft used. Clinical outcomes were assessed using the Kujala, International Knee Documentation Committee (IKDC), and Tegner-Lysholm scores. Radiological assessment included patellar tilt angle and congruence angle. Postoperative complications and recurrent patellar instability were also evaluated.

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Conditions studied

  • Recurrent Patellar Dislocation

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Keywords

  • Patellar Instability
  • Medial Patellofemoral Ligament
  • MPFL Reconstruction
  • Hamstring Tendon Graft
  • Quadriceps Tendon Graft
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In context

Patellar Dislocation

41 studies on the registry are indexed under Patellar Dislocation; 9 are open to participants now.

This study's enrollment of 38 is below the median of 100 across 15 observational studies indexed under Patellar Dislocation.

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Lead sponsor

Cairo University is the lead sponsor of 4,941 studies on the registry; 1,458 are open to participants now.

Of its 37 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with recurrent patellar instability who underwent medial patellofemoral ligament reconstruction using either a hamstring tendon graft or a quadriceps tendon graft.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients with recurrent patellar dislocation.
  • Age from 18 to 40 years.
  • Patients indicated for isolated medial patellofemoral ligament (MPFL) reconstruction.

Exclusion criteria

Exclusion Criteria:

  1. Patients with trochlear dysplasia (Dejour B-C-D).
  2. Patients with clinical evidence of mal-alignment (varus, valgus, flat foot and femoral anteversion).
  3. Patients with congenital pateller dislocation.
  4. Patella alta and patella baja.
  5. Previous quadriceps muscles operation.
  6. Patients with patellofemoral OA.
  7. Patients with hypermobility syndrome.
  8. Patients with associated pathology.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
38 participants (actual)
Patient registry
No

Groups and cohorts

  • Hamstring Tendon Graft Group

    Patients who underwent MPFL reconstruction using a hamstring tendon graft.

    Procedure: MPFL Reconstruction Using Hamstring Tendon Graft

  • Quadriceps Tendon Graft Group

    Patients who underwent MPFL reconstruction using a quadriceps tendon graft.

    Procedure: MPFL Reconstruction Using Quadriceps Tendon Graft

Interventions

  • ProcedureMPFL Reconstruction Using Hamstring Tendon Graft

    Medial patellofemoral ligament reconstruction was performed using an autologous semitendinosus tendon graft. The graft was fixed to the medial aspect of the patella and passed between layers 2 and 3 of the medial knee structures, followed by femoral fixation at the anatomical MPFL insertion.

  • ProcedureMPFL Reconstruction Using Quadriceps Tendon Graft

    Medial patellofemoral ligament reconstruction was performed using a distally based superficial quadriceps tendon graft. The graft remained attached to the superior pole of the patella, was passed between layers 2 and 3 of the medial knee structures, and was fixed at the anatomical femoral insertion of the MPFL.

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What researchers measure

Primary outcomes

  1. Kujala score

    Functional outcome assessed using the Kujala anterior knee pain scale. The score ranges from 0 to 100, with higher scores indicating better knee function and fewer patellofemoral symptoms.

    Time frame: 12 months postoperatively

Secondary outcomes

  1. International Knee Documentation Committee (IKDC) Score

    Knee function was assessed using the International Knee Documentation Committee (IKDC) score. Scores range from 0 to 100, with higher scores indicating better knee function.

    Time frame: 12 months postoperatively

  2. Tegner-Lysholm Knee Score

    Knee function was assessed using the Tegner-Lysholm knee score. Scores range from 0 to 100, with higher scores indicating better knee function.

    Time frame: 12 months postoperatively

  3. Patellar Tilt Angle

    Patellar tilt angle was measured radiologically to assess patellofemoral alignment before and after MPFL reconstruction.

    Time frame: 12 months postoperatively

  4. Congruence Angle

    Congruence angle was measured radiologically to assess patellofemoral alignment before and after MPFL reconstruction.

    Time frame: 12 months postoperatively

  5. Incidence of Re-dislocation

    Number of cases who experienced re-dislocation after MPFL reconstruction

    Time frame: 12 months postoperatively

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Study locations

1 site
  • Cairo University Hospitals (Kasr Al-Ainy)
    Cairo, Egypt
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 25, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07785570
Lead sponsor
Cairo University
Responsible party
Mahmoud Ahmed El-Desouky (Associate Professor, Cairo University) — Principal investigator
First posted
Aug 25, 2026
Start date
Jun 1, 2018
Primary completion
Jun 1, 2022
Completion
Jun 1, 2022
Last update
Aug 25, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.

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