An observational study in Gout and Coronary Atheroma, sponsored by The Affiliated Hospital of Qingdao University. Not yet recruiting at 1 site in China. Open to participants aged 18 Years to 90 Years. Per ClinicalTrials.gov, last updated 2026-08-25.
Sponsored by The Affiliated Hospital of Qingdao University · Observational
This observational study aims to evaluate the association between sodium urate deposition volume and coronary atherosclerotic plaques in patients with foot gout using dual-energy CT (DECT) and coronary CTA. This study will explore imaging-based evidence for the progression and risk prediction of adverse cardiovascular events in patients with gout.
Gout is a common form of inflammatory arthritis characterized by the deposition of monosodium urate crystals in joints and other tissues. This condition triggers an acute inflammatory response; over time, it can increase the incidence and disability associated with chronic gout. Beyond the musculoskeletal system, gout is also linked to an elevated risk of cardiovascular diseases (e.g., coronary artery disease). Chronic inflammation and endothelial dysfunction are the primary mechanisms underlying this association. In recent years, dual-energy computed tomography (DECT) has enabled the direct detection of MSU deposits in the ankle joint and coronary artery walls, which may serve as one of the driving factors for plaque inflammation and rupture. DECT utilizes distinct energy absorption spectra to differentiate MSU deposits from other substances, providing an non-invasive method for assessing the extent of MSU crystal deposition. It has been demonstrated that DECT can be accurately employed to identify MSU deposits within larger anatomical structures-such as urate crystals in peripheral joints-as well as to detect MSU within coronary artery plaques. In conclusion, monitoring the relationship between gout burden and the severity of atherosclerosis in patients with podagra can serve as an imaging-based reference for predicting the risk of cardiovascular adverse events in these patients.
345 studies on the registry are indexed under Gout; 49 are open to participants now.
This study's planned enrollment of 200 is below the median of 232 across 52 observational studies indexed under Gout.
Browse Gout studies →The Affiliated Hospital of Qingdao University is the lead sponsor of 149 studies on the registry; 56 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with podagra who have high-risk factors for cardiovascular disease
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraception
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Perform DECT and CCTA examinations on the patient
Volume of sodium urate deposition and coronary artery plaque volume
Measurement of sodium urate deposition volume and coronary artery plaque volume in patients with foot gout.
Time frame: baseline
Plan to share: No
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
The Affiliated Hospital of Qingdao University →