An interventional study of Talk2gether program in Social Isolation or Loneliness, sponsored by The University of Texas Health Science Center, Houston. Not yet recruiting at 1 site in United States. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2026-08-24.
Sponsored by The University of Texas Health Science Center, Houston · Not applicable, Interventional, and Supportive care
The purpose of this study is to see if it is feasible to recruit and retain older adults in a, weekly phone call program delivered through the Harris County Precinct 2 Healthcare and Social Services Team and to see how participation in the program affect older adults' loneliness, social isolation, psychological well-being, and satisfaction, and what barriers or challenges arise during implementation
236 studies on the registry are indexed under Social Isolation; 61 are open to participants now.
This study's planned enrollment of 50 is below the median of 80 across 198 interventional studies indexed under Social Isolation.
Browse Social Isolation studies →The University of Texas Health Science Center, Houston is the lead sponsor of 897 studies on the registry; 214 are open to participants now.
Of its 173 completed or terminated interventional studies of FDA-regulated products, 142 (82%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Behavioral: Talk2gether program
Participants will be paired with a trained team member. The team member will then initiate contact with the older adult(s) to begin 90 days of weekly social calls. These weekly social calls will be mostly unstructured, but supported by resource and conversation guides. At the end of 90 days, if the older adult wishes to continue to receive calls, that request will be accommodated
Program Feasibility as assessed by number of participants recruited
Time frame: end of intervention (90 days after baseline)
Program Feasibility as assessed by number of participants that adhered to the weekly calls
Time frame: end of intervention (90 days after baseline)
Feasibility as assessed by number of participants that completed the program
Time frame: end of intervention (90 days after baseline)
Feasibility as assessed by number of participants that encountered barriers or challenges as assessed by the Client Satisfaction Questionnaire (CSQ-8)
This is an 8 item questionnaire and Items 2, 4, 5, and 8 are reverse scored. Total scores range from 8 to 32, with the higher number indicating greater satisfaction
Time frame: end of intervention (90 days after baseline)
Feasibility as assessed by number of participants that encountered barriers or challenges as reported on the Caller and Older Adult feedback form
Time frame: end of intervention (90 days after baseline)
Change in social connectedness as assessed by the Lubben Social Network Scale-6
This is a 6-item self-report measure assessing perceived social support and social network size from family and friends. Each item is scored from 0 to 5, and total scores range from 0 to 30. Higher scores indicate greater social connectedness and lower risk of social isolation
Time frame: baseline, post-intervention (Day 90)
Change in loneliness as assessed by the Patient-Reported Outcomes Measurement Information System (PROMIS) Social Isolation scale
This is an 8 item scale. Each item is rated on a 5-point scale from 1(never) to 5 ( always). Raw scores range from 8 to 40 and are converted to PROMIS T-scores, with a mean of 50 and standard deviation of 10 in the reference population. Higher scores indicate greater perceived social isolation/loneliness.
Time frame: Baseline, end of intervention (90 days)
Change in depressive symptoms as assessed by the Patient Health Questionnaire-2
This is a 2-item self-report measure . Each item is scored from 0 (not at all) to 3 (nearly every day). Total scores range from 0 to 6, with higher scores indicating greater depressive symptom burden.
Time frame: Baseline, end of intervention (90 days)
Change in signs of elder mistreatment as assessed by the Elder Mistreatment Screening and Response Tool (EM-SART).
This is a 3 item questionnaire and each will be scored as either 1(yes) or 0(no) for a maximum score of 3. Higher scores or more endorsed concerns indicate a greater number of signs suggestive of elder mistreatment
Time frame: Baseline, end of intervention (90 days)
Change in sense of purpose using the 7-item Ryff Purpose in Life Scale.
This is a 7 item questionnaire and each item is rated on a Likert-type scale, commonly from 1(strongly disagree) to 6( strongly agree). Negatively worded items are reverse scored, and item scores are summed to generate a total score. Total scores range from 7 to 42, with higher scores indicating a greater sense of purpose in life.
Time frame: Baseline, end of intervention (90 days)
Client satisfaction as assessed by the Client Satisfaction Questionnaire
This is an 8 item questionnaire. Scores are summed across items once. Items 2, 4, 5, and 8 are reverse scored. Total scores range from 8 to 32, with the higher number indicating greater satisfaction
Time frame: end of intervention (90 days)
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Aug 2026; primary completion for Aug 2028, 24 months later.
Of 155 non-industry interventional studies with no phase under Social Isolation, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 36. This study's planned 24 months is above that.
Counting every sponsor, half of 156 studies reached it within 18 months; a quarter within 10 and three quarters within 36.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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The University of Texas Health Science Center, Houston →