An observational study in Chronic Cervical Radicular Pain, sponsored by Marmara University. Active, not recruiting at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2026-08-20.
Sponsored by Marmara University · Observational
This observational study aims to determine whether electromyography and nerve conduction study findings can help predict the response to cervical dorsal root ganglion pulsed radiofrequency treatment in patients with chronic cervical radicular pain. Adults aged 18 to 75 years with unilateral cervical radicular pain who are already scheduled to receive pulsed radiofrequency treatment will undergo an electrophysiological evaluation before the procedure. Participants will be classified according to whether cervical radiculopathy is detected on electrophysiological testing. Pain intensity, neck-related disability, quality of life, and depressive symptoms will be assessed before treatment and at 3 weeks, 3 months, and 6 months after the procedure. Outcomes will be compared between participants with and without electrophysiological evidence of radiculopathy to evaluate whether these findings are associated with treatment success.
483 studies on the registry are indexed under Radiculopathy; 145 are open to participants now.
This study's enrollment of 20 is below the median of 100 across 95 observational studies indexed under Radiculopathy.
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The study population consists of adults aged 18 to 75 years with unilateral chronic cervical radicular pain lasting at least 3 months due to cervical disc herniation and/or spinal stenosis. Eligible participants have persistent symptoms despite conservative treatments and are already scheduled to undergo cervical dorsal root ganglion pulsed radiofrequency treatment as part of routine clinical care. Before treatment, all participants undergo electromyography and nerve conduction studies and are classified according to the presence or absence of electrophysiological evidence of cervical radiculopathy.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Age between 18 and 75 years Presence of cervical disc herniation and/or spinal stenosis Unilateral cervical radicular pain radiating to the arm for at least 3 months, confirmed by clinical evaluation, physical examination, and radiological imaging Inadequate response to conservative treatments, including physical therapy, medical treatment, and/or epidural injection
Exclusion Criteria:
History of cervical spine surgery Presence of myelopathy Predominantly axial neck pain Active infection Vertebral fracture Coagulation disorder Presence of a cardiac pacemaker Refusal or inability to provide
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants with chronic unilateral cervical radicular pain in whom cervical radiculopathy is detected by baseline electromyography and nerve conduction studies. Participants receive cervical dorsal root ganglion pulsed radiofrequency treatment as part of routine clinical care and are followed for 6 months.
Participants with chronic unilateral cervical radicular pain in whom cervical radiculopathy is not detected by baseline electromyography and nerve conduction studies. Participants receive cervical dorsal root ganglion pulsed radiofrequency treatment as part of routine clinical care and are followed for 6 months
Change From Baseline in Pain Intensity Assessed by the Numeric Rating Scale
Pain intensity will be assessed using an 11-point Numeric Rating Scale ranging from 0, indicating no pain, to 10, indicating the worst imaginable pain. Change from baseline will be calculated at each follow-up visit and compared between participants with and without electrophysiological evidence of cervical radiculopathy. A greater reduction in score indicates greater improvement in pain.
Time frame: Baseline, 3 weeks, 3 months, and 6 months after cervical dorsal root ganglion pulsed radiofrequency treatment
Treatment Success Based on the Numeric Rating Scale
Treatment success is defined as a reduction of at least 50% in the Numeric Rating Scale pain score compared with baseline. The proportion of participants achieving treatment success will be compared between participants with and without electrophysiological evidence of cervical radiculopathy.
Time frame: 3 weeks, 3 months, and 6 months after cervical dorsal root ganglion pulsed radiofrequency treatment
Change From Baseline in Neck-Related Disability Assessed by the Neck Disability Index
Neck-related disability will be assessed using the Neck Disability Index. Higher scores indicate greater neck-related disability. Change from baseline will be calculated at each follow-up visit and compared between participants with and without electrophysiological evidence of cervical radiculopathy.
Time frame: Baseline, 3 weeks, 3 months, and 6 months after cervical dorsal root ganglion pulsed radiofrequency treatment
Change From Baseline in Health-Related Quality of Life Assessed by EuroQol
Health-related quality of life will be assessed using the EuroQol questionnaire. The instrument evaluates mobility, self-care, usual activities, pain or discomfort, and anxiety or depression. It also includes a visual analog scale ranging from 0 to 100, with higher scores indicating better perceived health status. Changes from baseline will be compared between the two electrophysiological groups.
Time frame: Baseline, 3 weeks, 3 months, and 6 months after cervical dorsal root ganglion pulsed radiofrequency treatment
Change From Baseline in Depressive Symptoms Assessed by the Beck Depression Inventory
Depressive symptoms will be assessed using the 21-item Beck Depression Inventory. Total scores range from 0 to 63, with higher scores indicating more severe depressive symptoms. Change from baseline will be calculated at each follow-up visit and compared between participants with and without electrophysiological evidence of cervical radiculopathy.
Time frame: Baseline, 3 weeks, 3 months, and 6 months after cervical dorsal root ganglion pulsed radiofrequency treatment
Plan to share: No
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This study is active, not recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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