ClinicalTrials.gg
CompletedNCT07773857Updated Aug 31, 2026

Comparison of Proprioceptive Neuromuscular Facilitation and Patient Education in Upper Crossed Syndrome

An interventional study of Patient Education and PNF in Upper Crossed Syndrome, Forward Head Posture and Rounded Shoulder Posture, sponsored by Atlas University. Completed at 1 site in Turkey (Türkiye). Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-31.

Sponsored by Atlas University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 5 months after the study started (first participant enrolled Mar 2026, registered Aug 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

The aim of this study is to investigate the effects of exercises applied using the Proprioceptive Neuromuscular Facilitation (PNF) technique on pain, joint range of motion, muscle strength, and posture in individuals with Upper Crossed Syndrome, and to compare these effects with patient education. Individuals diagnosed with Upper Crossed Syndrome will be included in the study and allocated into two groups: a PNF-based exercise combined with patient education group and a patient education-only group.

In the PNF group, Stabilizing Reversals for scapular anterior elevation-posterior depression and Replication techniques for posterior depression will be applied. In the patient education group, education including postural awareness and exercise will be provided. Assessments will be conducted at two time points, before and after the intervention. Pain level, joint range of motion, muscle strength and endurance, and postural parameters will be analyzed.

This study is expected to provide evidence regarding the clinical effectiveness of PNF approaches targeting scapular control in individuals with Upper Crossed Syndrome and to contribute to the management of postural disorders in the field of physiotherapy and rehabilitation.

02

Conditions studied

  • Upper Crossed Syndrome
  • Forward Head Posture
  • Rounded Shoulder Posture
  • Hyperkyphosis
  • Kyphosis

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Keywords

  • Upper Cross Syndrome
  • Proprioseptive Neuromuscular Facilitatiton
  • PNF
  • Patient Education
  • Posture
03

In context

Kyphosis

132 studies on the registry are indexed under Kyphosis; 31 are open to participants now.

This study's enrollment of 38 is below the median of 44 across 82 interventional studies indexed under Kyphosis.

Browse Kyphosis studies →

Lead sponsor

Atlas University is the lead sponsor of 96 studies on the registry; 25 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age 18 years or older
  • Clinically diagnosed with Upper Crossed Syndrome and referred by a specialist physician (e.g., Physical Medicine and Rehabilitation, Orthopedics)
  • Upper Crossed Syndrome diagnosis confirmed at baseline based on postural characteristics (e.g., forward head posture, rounded shoulders, thoracic kyphosis etc.)
  • Willingness to participate in the study and provision of written

Exclusion criteria

Exclusion Criteria:

  • History of spinal surgery or spinal fracture
  • Presence of structural spinal deformities (e.g., structural kyphosis or scoliosis)
  • Presence of neuromuscular diseases affecting the spine or upper quadrant
  • Presence of congenital or acquired severe structural spinal anomalies
  • Any medical condition that contraindicates participation in exercise programs
  • History of severe psychiatric disorders
  • History of chronic pain in the cervical or lumbopelvic regions
  • History of postural control disorders
  • Any condition expected to prevent regular participation or adherence during the study period.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
38 participants (actual)

Study arms

  • Active comparator
    Patient Education Group

    Participants in the patient education group will receive a single face-to-face patient education session at the beginning of the study.

    Behavioral: Patient Education

  • Experimental
    PNF Group

    In the PNF group, in addition to patient education, Stabilizing Reversals and Replication techniques with scapular patterns will be performed.

    Behavioral: Patient Education · Behavioral: PNF

Interventions

  • BehavioralPatient Education

    Participants in the patient education group will receive a single face-to-face patient education session at the beginning of the study. This education will include information on postural awareness, correct sitting posture, and maintaining proper posture during activities of daily living. In addition, participants will be provided with a prepared educational brochure and will be asked to perform the two postural exercises included in the brochure three days per week for a total duration of four weeks. Participants will be encouraged to integrate the postural principles taught during the education into their daily lives.

  • BehavioralPNF

    In the PNF, trunk correction in the sitting position, approximation, and the application of Stabilizing Reversals in the direction of scapular posterior depression-anterior elevation and Replication techniques toward scapular posterior depression in the side-lying position will be performed. These interventions are planned to be applied three days per week, with a total intervention duration of four weeks.

06

What researchers measure

Primary outcomes

  1. Posture Assesment

    Posture will be assessed using the Posture Screen Mobile (PSM) application (Backbone Software, Inc., USA), a valid and reliable mobile application designed for postural analysis. Participants will be positioned in a static standing posture on a flat surface, with their feet parallel, wearing appropriate clothing that allows visualization of the upper body and lower extremities. Photographs will be taken from the anterior, posterior, and lateral views using a mobile device placed at a standardized distance. During the assessment, the application will automatically identify anatomical reference points (e.g., ears, shoulders, pelvis). Based on these reference points, postural deviations will be calculated and reported by the software. Anterior and posterior postural deviations in the frontal plane and lateral postural deviations in the sagittal plane will be recorded for each participant.

    Time frame: Baseline and up to 8 weeks

Secondary outcomes

  1. Muscle Strength Assessment

    Muscle strength of the thoracic back extensor muscles and abdominal muscles (upper, lower, and oblique abdominal muscles) will be assessed before and after the intervention using manual muscle testing performed by the same physiotherapist (Scoring 0-5). Upper abdominal muscle strength will be evaluated in the supine position using graded trunk flexion tasks with varying arm positions as resistance. Lower abdominal muscle strength will be assessed in the supine position by recording the ability to maintain lumbopelvic stability while the lower extremities are slowly lowered from 90° hip flexion. Oblique abdominal muscle strength will be evaluated through trunk flexion combined with rotation, with scoring based on movement quality and scapular clearance criteria.

    Time frame: Baseline and up to 8 weeks

  2. Pain Assessment

    The level of back pain will be assessed using the Visual Analog Scale (VAS). The VAS consists of a 10-cm horizontal line, with the endpoints labeled "no pain" and "unbearable pain." Participants will be asked to mark the point on the scale that best represents the intensity of their pain. Pain intensity will be determined by measuring the distance in centimeters from the "no pain" anchor to the participant's mark.

    Time frame: Baseline and up to 8 weeks

  3. Muscle Endurance

    Muscle endurance of the thoracic and lumbar back extensor muscles and the abdominal muscles (upper, lower, and oblique abdominal muscles) will be assessed. Endurance of the thoracic and lumbar back extensors will be evaluated using the Biering-Sorensen Test, a valid and reliable method for assessing isometric endurance of spinal extensor muscles. The duration for which the test position can be maintained will be recorded in seconds. Abdominal muscle endurance will be assessed by recording the holding time (in seconds) at the final position of the highest achievable manual muscle test score. Upper abdominal muscle endurance will be evaluated using the Bench Trunk Curl Test, oblique abdominal muscle endurance will be measured using the Flexion-Rotation Trunk Endurance Test, and lower abdominal muscle endurance will be assessed by recording the duration for which an isometric position requiring lumbopelvic stability can be maintained.

    Time frame: Baseline and up to 8 weeks

  4. Muscle Length Tests

    Muscle length tests will be performed for the following muscle groups. Pectoralis Major (sternal and clavicular portions): Muscle length will be assessed in the supine position by measuring the distance between the lateral epicondyle of the humerus and the examination table on both sides. The upper limb will be positioned in shoulder external rotation with standardized abduction angles (135° for the sternal portion and 90° for the clavicular portion) and elbow extension. The measured distance will be recorded as an indicator of muscle tightness. Pectoralis Minor: Muscle length will be evaluated in the supine position by measuring the distance between the acromion and the examination table bilaterally. Greater distances will indicate increased muscle tightness. Hamstring Muscles: Hamstring muscle length will be assessed bilaterally using the straight leg raise test in the supine position. Hip flexion range of motion will be measured with a universal goniometer and recorded in degree

    Time frame: Baseline and up to 8 weeks

  5. Range of Motion Assessment

    Trunk range of motion, including flexion, extension, lateral flexion, and rotation, will be assessed using a goniometric method. Measurements will be recorded in degrees using Saehan steel goniometers. Trunk flexion and extension will be measured in the standing position, with the goniometer aligned to anatomical landmarks of the lumbosacral region. Trunk lateral flexion will be assessed in standing, with the goniometer positioned to follow the spinal alignment. Trunk rotation will also be measured in the standing position, and the angle achieved during rotation will be recorded in degrees.

    Time frame: Baseline and up to 8 weeks

  6. Flexibility Tests

    Trunk flexion flexibility will be assessed using the sit-and-reach test. Participants will be seated on a firm surface with the knees extended and instructed to reach forward toward their feet without bending the knees. The distance reached will be measured in centimeters using a measuring tape. Trunk extension, lateral flexion, and rotation flexibility will be assessed in the standing position. The distances achieved in the respective movement directions will be measured in centimeters using a measuring tape and recorded.

    Time frame: Baseline and up to 8 weeks

07

Study locations

1 site
  • Istanbul Atlas University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation
    Istanbul, Istanbul 34408, Turkey (Türkiye)
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Mar 2026 to primary completion in Jun 2026, 3 months.

Of 56 non-industry interventional studies with no phase under Kyphosis, half reached primary completion within 9 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 30. This study's 3 months is below that.

Counting every sponsor, half of 58 studies reached it within 9 months; a quarter within 4 and three quarters within 30.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 14, 2026
First posted
Aug 19, 2026
StartActual
Mar 5, 2026
Primary completionActual
Jun 15, 2026
CompletionActual
Jul 15, 2026
Last update
Aug 31, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 31, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07773857
Lead sponsor
Atlas University
Responsible party
Sponsor
First posted
Aug 19, 2026
Start date
Mar 5, 2026
Primary completion
Jun 15, 2026
Completion
Jul 15, 2026
Last update
Aug 31, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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