An interventional study of Group A= Neural Gliders with ESWT and Group B= Neural Gliders without ESWT in Deep Gluteal Syndrome, sponsored by University of Management and Technology Sialkot Pakistan. Enrolling by invitation at 1 site in Pakistan. Open to participants aged 25 Months to 45 Years. Per ClinicalTrials.gov, last updated 2026-08-21.
Sponsored by University of Management and Technology Sialkot Pakistan · Not applicable, Interventional, and Treatment
This study is a randomized controlled trial comparing Neural Gliders with and without Extracorporeal Shock Wave Therapy (ESWT) in patients with Deep Gluteal Syndrome. A total of 44 participants are divided equally into two groups: Group A receives neural gliders, ESWT, and conventional physiotherapy, while Group B receives neural gliders with conventional physiotherapy only. The study evaluates changes in pain, functional disability, and nerve mechano-sensitivity using NPRS, ODI, LEFS, Slump Test, FAIR Test, and SLR. Its aim is to determine whether adding ESWT provides greater clinical improvement than neural gliders alone.
This study is a randomized controlled trial designed to compare the effects of Neural Gliders with and without Extracorporeal Shock Wave Therapy (ESWT) in patients with Deep Gluteal Syndrome (DGS). A total of 44 participants will be randomly divided into two equal groups of 22. Group A will receive neural gliding exercises combined with ESWT and conventional physiotherapy, while Group B will receive neural gliding exercises with conventional physiotherapy only. The conventional treatment includes a hot pack and piriformis stretching. The main outcomes are pain intensity, functional disability, lower-limb function, and nerve mechano-sensitivity, assessed using the NPRS, ODI, LEFS, Slump Test, FAIR Test, and Straight Leg Raise (SLR). The intervention is planned for 3 sessions per week for 4 weeks, and the study aims to determine whether adding ESWT to neural gliders provides greater improvement in pain, function, and nerve mobility than neural gliders alone.
University of Management and Technology Sialkot Pakistan is the lead sponsor of 8 studies on the registry; 6 are open to participants now.
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Exclusion Criteria:
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Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
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Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
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Cancer (malignancy)
Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.
Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Arm Description: Participants in Group A will receive neural gliding exercises combined with radial Extracorporeal Shock Wave Therapy (ESWT) along with standardized conventional physiotherapy. Neural gliders will be performed in supine lying with the hip flexed, while ESWT will be applied over the piriformis/deep gluteal region. Neural gliding will be performed as 2 sets of 10 repetitions, and ESWT will be delivered at 2000 shocks per session with a frequency of 10-15 Hz. Treatment will be given 4 sessions per week for 6 weeks, with both groups also receiving a hot pack and piriformis stretching.
Other: Group A= Neural Gliders with ESWT
Arm Description: Participants in Group B will receive Neural Gliding exercises without ESWT, along with standardized conventional physiotherapy. Neural gliders will be performed in supine lying with the hip flexed, targeting the piriformis region and sciatic nerve pathway. The exercises will be performed as 2 sets of 10 repetitions, with treatment provided 4 sessions per week for 6 weeks. Conventional physiotherapy will include a 10-minute hot pack and piriformis stretching, with no ESWT applied in this group
Other: Group B= Neural Gliders without ESWT
We use Neural Gliders in Deep Gluteal Syndrome because the sciatic nerve can become irritated or restricted as it passes through the deep gluteal region. Neural gliding produces gentle alternating movements that allow the nerve to slide within its pathway, helping improve nerve mobility, reduce mechano-sensitivity, improve circulation around the nerve, and decrease pain and functional limitation. We combine Neural Gliders with ESWT because the two interventions target different components of the problem. Neural gliders mainly address nerve mobility and sensitivity, while ESWT is intended to act on the surrounding deep gluteal/piriformis tissues by helping reduce pain, improve blood flow, decrease tissue tightness, and stimulate healing.
We use neural gliders to improve sciatic nerve mobility and reduce nerve mechano-sensitivity. We add ESWT because it may reduce pain, improve circulation, and treat tight or restricted deep gluteal tissues. Therefore, the combination may address both the nerve and the surrounding soft tissues more effectively."
Universal Gonimeter
A Universal Goniometer is a simple clinical instrument used to measure joint range of motion in degrees. It consists of a central axis or fulcrum with one stationary arm and one movable arm, which are aligned with anatomical landmarks during measurement. In this study, the goniometer is used during the Straight Leg Raise (SLR) test to record the angle at which pain, tightness, or neural symptoms appear. A lower SLR angle indicates greater restriction or nerve mechano-sensitivity, while an increased angle after treatment suggests improved nerve mobility and functional recovery.
Time frame: 6 weeks
NPRS
The NPRS is simple 0-10 scale used to measure pain intensity. Patients rate their pain where 0=no pain and 10=worst possible pain. In your study, it helps track changes in buttock and leg caused by deep gluteal syndrome. A score reduction after treatment indicates improvement. Clinically, a change of ≥ 2 points is considered meaningful
Time frame: 6 weeks
LEFS
The Lower Extremity Functional Scale (LEFS) is a patient-reported outcome measure utilized to evaluate functional impairments in individuals with lower extremity musculoskeletal disorders .
Time frame: 6 WEEKS
Plan to share: Undecided
Start is estimated for Aug 2026; primary completion for Aug 2026, 0 months later.
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Hip socket neuropathy
University of Management and Technology Sialkot Pakistan