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CompletedNCT07766252Updated Aug 14, 2026

CCHW-delivered CFH-based Cancer Prevention Program Among Chinese Americans

An interventional study of Family Health History-Based Cancer Prevention and Navigation Program in Cancer, sponsored by Texas A&M University. Completed at 1 site in United States. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-14.

Sponsored by Texas A&M University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
1,129
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

This study evaluated a culturally and linguistically tailored cancer prevention program delivered by trained Chinese American community health workers to Chinese American adults in Texas. The program focused on breast, colorectal, gastric, liver, and lung cancers and used family health history to provide personalized education and navigation. The study examined whether the program could improve participants' cancer-related knowledge, family health history communication, preventive behaviors, cancer screening, and use of genetic services. The investigators hypothesized that participants would show improvements in these outcomes after receiving the program compared with before the program.

02

Conditions studied

  • Cancer

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Keywords

  • Prevention
  • community health worker
  • family health history
  • Chinese American
  • genetics
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Self-identified as Chinese Americans; aged 18 or above; who could speak, listen, read, and write Mandarin Chinese; who lived in Texas; and who agreed to receive the intervention provided by community health workers

Exclusion criteria

Exclusion Criteria:

  • None specified
04

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
1,129 participants (actual)

Study arms

  • Experimental
    Intervention group

    Behavioral: Family Health History-Based Cancer Prevention and Navigation Program

Interventions

  • BehavioralFamily Health History-Based Cancer Prevention and Navigation Program

    Trained Chinese American community health workers delivered a culturally and linguistically tailored, family health history-based cancer prevention and navigation program to Chinese American adults in Texas. Participants received individualized education about breast, colorectal, gastric, liver, and lung cancer; guidance on how to collect and understand their cancer family health history; and personalized recommendations based on their reported cancer risks and health behaviors. When appropriate, participants were encouraged to discuss their risk with healthcare providers, complete recommended cancer screening, and seek genetic counseling or other genetic services.

05

What researchers measure

Primary outcomes

  1. Change from Baseline in Cancer Family Health History Communication Behaviors at 3 Months

    Participants reported how often they learned about and discussed their cancer family health history with family members and healthcare providers. Items were rated from 1 (never) to 5 (always). Higher scores indicate more frequent family health history communication.

    Time frame: Baseline and 3 months after the intervention

  2. Change from Baseline in Completion of Recommended Cancer Screening at 3 Months

    Average-risk participants reported whether they had completed recommended cancer screenings. Screening completion was coded as yes or no based on whether the participant met the applicable screening recommendation.

    Time frame: Baseline and 3 months after the intervention

  3. Change from Baseline in Cigarette Smoking at 3 Months

    Participants who reported smoking indicated the average number of cigarettes smoked per day. Lower values indicate lower tobacco consumption.

    Time frame: Baseline and 3 months after the intervention

  4. Change from Baseline in Moderate Aerobic Exercise at 3 Months

    Participants reported the average number of minutes of moderate aerobic exercise performed per week. Higher values indicate more physical activity.

    Time frame: Baseline and 3 months after the intervention

  5. Change from Baseline in Alcohol Consumption at 3 Months

    Participants reported the average number of alcoholic drinks consumed per week. One drink was defined as approximately 12 oz of beer, 5 oz of wine, or 1.5 oz of spirits. Lower values indicate lower alcohol consumption.

    Time frame: Baseline and 3 months after the intervention

  6. Change from Baseline in Fruit and Vegetable Intake at 3 Months

    Participants reported average daily fruit and vegetable intake using an 8-category scale ranging from 1 (less than 0.5 cup per day) to 8 (4 cups or more per day). Higher scores indicate greater fruit and vegetable intake.

    Time frame: Baseline and 3 months after the intervention

  7. Change from Baseline in Consumption of Meat and Preserved Foods at 3 Months

    Participants reported average weekly consumption of red meat, processed meat, salty foods, preserved foods, and high-temperature cooked meat. Consumption was expressed as the number of palm-sized servings per week, with one palm-sized serving representing approximately 3 ounces of food. Lower values indicate lower consumption.

    Time frame: Baseline and 3 months after the intervention

  8. Change from Baseline in Cancer-Related Cooking Practices at 3 Months

    Participants reported the frequency of cancer-related cooking practices, including high-temperature cooking, deep frying, and use of an Asian-style kitchen range hood. Items were rated from 1 (never) to 5 (always).

    Time frame: Baseline and 3 months after the intervention

  9. Change from Baseline in Cancer-Related Chemical Exposures at 3 Months

    Participants reported the frequency of environmental and occupational exposures to chemicals associated with lung and liver cancer. Items were rated from 1 (never) to 5 (always). Higher scores indicate more frequent exposure.

    Time frame: Baseline and 3 months after the intervention

  10. Change from Baseline in Body Mass Index at 3 Months

    Body mass index was calculated from participant-reported height and weight as weight in kilograms divided by height in meters squared (kg/m\^2).

    Time frame: Baseline and 3 months after the intervention

  11. Number of High-Risk Participants Who Used Genetic Services by 3 Months

    Among participants identified as having increased cancer risk based on their reported family health history, this outcome measured the number who reported visiting a genetics provider for genetic counseling, genetic risk evaluation, or genetic testing within three months after the intervention.

    Time frame: 3 months after the intervention

Secondary outcomes

  1. Participant Satisfaction With the Cancer Prevention and Navigation Program

    Participants rated their satisfaction with the cancer prevention services provided by their community health worker on a 4-point scale from 1 (very unsatisfied) to 4 (very satisfied). Higher scores indicate greater satisfaction.

    Time frame: Immediately after the intervention

  2. Change from Baseline in Cancer Family Health History Knowledge After the Intervention and at 3 Months

    Participants answered questions assessing cancer family health history knowledge and cancer risk. Each correct response was coded as 1, and incorrect or "not sure" responses were coded as 0. The mean of the item scores was calculated, resulting in a score ranging from 0 to 1. Higher scores indicate greater knowledge.

    Time frame: Baseline, immediately after the intervention, and 3 months after the intervention

  3. Change from Baseline in Cancer Family Health History and Cancer Screening Awareness After the Intervention and at 3 Months

    Participants rated their awareness of communicating cancer family health history and cancer screenings. Items were rated from 1 (never heard of it) to 4 (have heard of it). Higher scores indicate greater awareness.

    Time frame: Baseline, immediately after the intervention, and 3 months after the intervention

  4. Change from Baseline in Attitudes Toward Cancer Family Health History and Cancer Screening After the Intervention and at 3 Months

    Participants rated their attitudes toward communicating cancer family health history and taking recommended cancer screenings. Items were rated from 1 (strongly disagree) to 4 (strongly agree). Higher scores indicate more favorable attitudes.

    Time frame: Baseline, immediately after the intervention, and 3 months after the intervention

  5. Change from Baseline in Intention to Engage in Cancer Family Health History Communication and Cancer Screening After the Intervention and at 3 Months

    Participants rated their intention to communicate their cancer family health history and follow recommended cancer screenings. Items were rated from 1 (very unlikely) to 4 (very likely). Higher scores indicate stronger intention.

    Time frame: Baseline, immediately after the intervention, and 3 months after the intervention

  6. Change from Baseline in Cancer Family Health History Communication and Cancer Screening Self-Efficacy After the Intervention and at 3 Months

    Participants rated their confidence in communicating cancer family health history and following cancer screening recommendations. Items were rated from 0 (not confident at all) to 10 (completely confident). Higher scores indicate greater self-efficacy.

    Time frame: Baseline, immediately after the intervention, and 3 months after the intervention

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Study locations

1 site
  • Texas A&M University
    College Station, Texas 77840, United States
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT07766252
Lead sponsor
Texas A&M University
Responsible party
Lei-Shih Chen (Professor, Texas A&M University) — Principal investigator
First posted
Aug 14, 2026
Start date
Dec 1, 2019
Primary completion
Dec 15, 2020
Completion
Dec 31, 2020
Last update
Aug 14, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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