An interventional study of assessment in ACL Surgery, sponsored by Centre Hospitalier Metropole Savoie. Recruiting at 1 site in France. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2026-08-14.
Sponsored by Centre Hospitalier Metropole Savoie · Not applicable, Interventional, and Supportive care
The goal of this clinical trial is to to determine the extent of the association between objective changes in the muscle function of the knee extensors (strength and power) and the function reported by the patient following ACL reconstruction surgery. The main questions it aims to answer is:
- Pre- and post-operative (6 months) changes in maximum knee extensor strength following ACL reconstruction, correlated with the IKDC-SKF score.
Before surgery :
Centre Hospitalier Metropole Savoie is the lead sponsor of 22 studies on the registry; 8 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
assessment of knee function before and after cruciate ligament surgery
Other: assessment
* Assessment of force-velocity and power-velocity relationships in each leg during a cycling task * Assessment of unilateral force-velocity and power-velocity relationships during a knee extension task * Assessment of maximum force and explosive force in isometric (static) conditions of the knee extensors. * Measurement of scores using questionnaires (IKDC-SKF).
Correlation of maximum knee extension strength to IKDC-SKF scores
Relationship (r coefficient) between 0-6 month delta of maximum knee extension strength measurements and International Knee Documentation Commitee-SKF scores (100: no limitation)
Time frame: 6 month
Peri-operatory trajectory of maximal dynamic force
Trajectory of evolution of F0 (maximal dynamic force) between baseline, 3 and 6 months, compared between legs (linear mixed effect model).
Time frame: 0, 3 and 6 month
Peri-operatory trajectory of maximal contraction velocity
Trajectory of evolution of V0 (maximal contraction velocity) between baseline, 3 and 6 months, compared between legs (linear mixed effect model).
Time frame: 0, 3 and 6 month
Peri-operatory trajectory of rate of force development
Trajectory of evolution of rate of force development between baseline, 3 and 6 months, compared between legs (linear mixed effect model).
Time frame: 0, 3 and 6 month
Peri-operatory trajectory of maximal isometric force
Trajectory of evolution of maximal isometric force (Fmax) between baseline, 3 and 6 months, compared between legs (linear mixed effect model).
Time frame: 0, 3 and 6 month
Peri-operatory trajectory of maximal dynamic force during cycling
Trajectory of evolution of maximal dynamic force (F0) during cycling between baseline, 3 and 6 months (linear mixed effect model, one fixed factor).
Time frame: 0, 3 and 6 month
Peri-operatory trajectory of maximal contraction velocity during cycling
Trajectory of evolution of maximal contraction velocity (V0) during cycling between baseline, 3 and 6 months (linear mixed effect model, one fixed factor).
Time frame: 0, 3 and 6 month
Determinants of fonctional prognosis
Multivariate analysis including the IKDC-SKF score at 24 months as dependant variable and, as predictors : 1. the 0-3 month delta of V0, F0, RFD and Fmax during knee extension on the operated leg. 2. the severity of the lesion (presence of associated lesions) 3. the presence of a pre-operatory rehabilitation.
Time frame: 0, 3 and 24 month
Determinants of fonctional prognosis
Multivariate analysis including the recurrence of ACL lesion at 24 months (0/1) as dependant variable and, as predictors : 1. the 0-3 month delta of V0, F0, RFD and Fmax during knee extension on the operated leg. 2. the severity of the lesion (presence of associated lesions) 3. the presence of a pre-operatory rehabilitation.
Time frame: 0, 3 and 24 month
Determinants of fonctional prognosis
Multivariate analysis including resuming physical activity at the pre-injury level at 24 months (0/1) as dependant variable and, as predictors : 1. the 0-3 month delta of V0, F0, RFD and Fmax during knee extension on the operated leg. 2. the severity of the lesion (presence of associated lesions) 3. the presence of a pre-operatory rehabilitation.
Time frame: 0, 3 and 24 month
Plan to share: No
No publications or documents are linked to this record.
Started Jun 2026 (actual). Primary completion is estimated for Jun 2030, 48 months after the start.
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Centre Hospitalier Metropole Savoie