ClinicalTrials.gg
RecruitingNCT07760597FREQUpdated Aug 13, 2026

Effects of Exercise Frequency on Muscle Size and Strength in Healthy, Untrained Young Adults

An interventional study of 10 sessions per week of resistance training and Two sessions per week of resistance training in Healthy Adult Male and Female Volunteers, sponsored by Cameron Mitchell. Recruiting at 1 site in Canada. Open to participants aged 19 Years to 39 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-08-13.

Sponsored by Cameron Mitchell · Not applicable, Interventional, and Basic science

From the registry’s dates

  • Started Aug 2026; still recruiting 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
19 Years to 39 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 705 studies in Motor Activity with a site in Canada — 140 open to participants now, 168 under way, 2 of them phase 3. Motor Activity · Canada.

Planned enrollment
352nd of 661
40 · median 46
Started
2026
with 32 others
No phase
570 of 705
121 open now
Primary completion
2027-06
later than 119 of 167 live
Registered
695th of 705
by date

Among the 705 studies in Motor Activity with a site in Canada, this one is the 352nd largest by planned enrollment of the 661 interventional ones, is one of 33 that started in 2026, is one of 570 with no phase, reaches primary completion later than 119 of the 167 other live ones, and was the 695th registered.

By phase

705 studies; the count open now beside each. This study's row is marked.

No phasethis study570 · 121 open
Observational42 · 11 open
Phase 229 · 1 open
Phase 124 · 3 open
Phase 417 · 2 open
Phase 313 · 1 open
Phase 2/37 · 1 open
Phase 1/23 · 0 open

By the year they started

First in 1997; this study’s year is marked. 33 started in 2026.

Size and results

Median enrollment 46 across the 661 interventional studies, 50 across the 42 observational. Of the 473 that completed or were terminated, 41 (9%) have results posted.

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Watch this landscapeDownload CSVWith an account: a weekly mail of what changed among 705 studies in Motor Activity with a site in Canada, or all of them as a file.
02

Study summary

Resistance training (RT) is important for building and maintaining healthy muscles. An exercise frequency called "exercise snacks" involves short bursts of exercise throughout the day (\~5-15 minutes), but no studies have examined a gym-based RT exercise snack program. The invetigators will randomize 40 participants into one of two groups for 10 weeks: the control group will complete two full-body workouts per week (standard-frequency) and the experimental group will complete 10 mini-workouts per week (high-frequency). Muscle hypertrophy (size) and strength will be measured before and after the exercise program to determine if the participants had the same or different results.

03

Conditions studied

  • Healthy Adult Male and Female Volunteers

Browse trials for

Keywords

  • Exerise Snacks
  • Exercise Frequency
  • Resistance Training
  • Muscle Strength
  • Skeletal Muscle Enlargement
  • Exercise
04

Who can participate

Ages eligible
19 Years to 39 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Can fluently read and write in English
  • Lives, works, and/or studies at or near the Gateway Health Building (where all study visits will occur)
  • Willing and able to commit to 2 or 10 in-person training sessions per week for 10 continuous weeks, as well as one week of testing before the training period and one week of testing after the training period
  • Has continuous access to smartphone or other device that they can use to access the Technogym app
  • Answers "No" to all questions on the Canadian Society for Exercise Physiology - Get Active Questonnaire (CSEP-GAQ) or has their doctor's approval to participate

Exclusion criteria

Exclusion Criteria:

  • Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders
  • Lung disease, kidney disease, or liver disease
  • Current diagnosis of type 1 diabetes, type 2 diabetes, or cancer
  • Medical conditions that limit their ability to undertake strenuous physical activity
  • Regular use of any medications that may affect muscle physiology or body composition (i.e. benzodiazepines, hormone replacement therapy, ADHD medication, Metformin, Ozempic)
  • Participated in consistent resistance exercise training more than twice per month in the previous 12 months
  • Participated in consistent moderate or vigorous aerobic training more than twice per week in the previous 12 months, or planning to start consistent training in the next few months
  • Significant gain or loss of body mass in the past 6 months (greater than 2 kg)
  • Current smoker (including but not limited to cigarettes, e-cigarettes, or vaping)
  • of less than 18 kg/m2 or over 30 kg/m2
  • Pregnancy or breastfeeding
  • Currently taking blood thinners
  • Allergic to Tegaderm medical tape (used with the activity trackers)
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Active comparator
    Standard-frequency resistance training

    Behavioral: Two sessions per week of resistance training

  • Experimental
    High-frequency resistance training

    Behavioral: 10 sessions per week of resistance training

Interventions

  • Behavioral10 sessions per week of resistance training

    Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting. Training at an exercise frequency of 10 brief sessions per week (around 8-12 minutes per session).

  • BehavioralTwo sessions per week of resistance training

    Full-body resistance training consisting of 10 sets per week for all major muscle groups with progressive overload in a gym-based setting. Training at an exercise frequency of two sessions per week (around 45-60 minutes per session).

06

What researchers measure

Primary outcomes

  1. Change in Total Body Skeletal Muscle Mass Measured using the D3-Creatine Dilution Method

    Time frame: From enrolment (Week 1) to the end of the exercise training phase (Week 12)

Secondary outcomes

  1. Change in Total Body Muscle Size Measured as Cross-sectional Area using Muscle Ultrasound Imaging

    Muscle ultrasound imaging will be conducted on one randomly selected side of the body (left or right) for each participant. Scans will be analyzed to determine the cross-sectional area of the following seven muscles: rectus femoris, vastus lateralis, biceps brachii, pectoralis major, latissimus dorsi, triceps brachii, and hamstring group (semitendinosus, semimembranosus, and long head of biceps femoris).

    Time frame: From enrolment (Week 1) to the end of the exercise training phase (Week 12)

  2. Change in Muscle Strength Measured as the One-Repetition Maximum of Back Squat and Bench Press

    One-repetition maximums will be measured using a Quantum Synchro Smith Machine.

    Time frame: From enrolment (Week 1) to the end of the exercise training phase (Week 12)

  3. Change in Skeletal Muscle Power Measured at Various Relative Loads for Back Squat and Bench Press

    At enrolment (Week 1), power will be measured using a Quantum Synchro Smith Machine at 40%, 50%, 60%, 70%, and 80% of the participant's initial one-repetition maximum (1RM) for back squat and bench press. At the end of the exercise training phase (Week 12), if a participant's 1RM has increased by less than 25%, power will be measured at the same relative loads. If a participant's 1RM has increased by 25-49%, power will be measured at 50%, 60%, 70%, 80%, and 90% of the participant's initial 1RM (in this case, 90% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM). If a participant's 1RM has increased by 50% or greater, power will be measured at 60%, 70%, 80%, 90%, and 100% of the participant's initial 1RM (in this case, 100% of the participant's initial 1RM would not exceed 80% of the participant's post-training 1RM).

    Time frame: From enrolment (Week 1) to the end of the exercise training phase (Week 12)

  4. Participant Satisfaction with the Exercise Program

    Participant satisfaction with the exercise program will be measured using a modified Intrinsic Motivation Inventory (subscales of "Interest/Enjoyment", "Percieved Competence", "Effort/Importance", and "Value/Usefullness").

    Time frame: At the end of the exercise training phase (Week 12)

07

Study locations

1 of 1 sites recruiting
  • University of British Columbia | Gateway Health Building
    Vancouver, British Columbia V6T 1Z1, Canada
    Recruiting
08

References and documents

Individual participant data

Plan to share: No — The dataset will contain potentially identifying information (age, height, and weight) of people in a relatively small geographic area, so individual participant data will not be shared with other researchers.

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Aug 2026 (actual). Primary completion is estimated for Jun 2027, 10 months after the start.

Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's planned 10 months is below that.

Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.

How these figures are worked out, and which studies are left out of them.

Registered
Aug 7, 2026
First posted
Aug 12, 2026
StartActual
Aug 12, 2026
Primary completionEst.
Jun 2027
CompletionEst.
Jun 2027
Last update
Aug 13, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 13, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07760597
Lead sponsor
Cameron Mitchell
Responsible party
Cameron Mitchell (Associate Professor, University of British Columbia) — Sponsor-investigator
First posted
Aug 12, 2026
Start date
Aug 12, 2026
Primary completion
Jun 2027 (estimated)
Completion
Jun 2027 (estimated)
Last update
Aug 13, 2026

Study contacts

Cameron Mitchell, PhD
Contact
cameron.mitchell@ubc.ca
604-827-2072

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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