An observational study in Occupational Accidents and Weather, sponsored by Sergio Gabriel Susmallian. Active, not recruiting at 1 site in Israel. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-07.
Sponsored by Sergio Gabriel Susmallian · Observational
This study will determine whether extreme ambient temperatures increase the incidence and severity of occupational injuries in Israel, and we request Helsinki Committee approval to conduct the analysis using de-identified National Insurance and historical meteorological data, with a waiver of informed consent. The project will link the date, time, and geographic location of recognized occupational accidents with corresponding historical temperature and humidity measurements. The study is retrospective, observational, and involves no direct contact with participants, no intervention, and no alteration of medical care or benefit eligibility.
Occupational injuries represent an important source of preventable morbidity, permanent disability, loss of employment, and economic burden. Rising temperatures and increasingly frequent heatwaves may impair concentration, coordination, judgment, reaction time, hydration, and physical endurance, particularly among workers in construction, agriculture, transportation, manufacturing, and other outdoor or physically demanding occupations. However, the national relationship between ambient heat and work-related injury in Israel has not been adequately quantified. Without reliable population-level evidence, employers, occupational-health authorities, and policymakers cannot identify temperature thresholds at which preventive measures should be intensified or determine which workers and industries are at greatest risk.
Sergio Gabriel Susmallian is the lead sponsor of 5 studies on the registry; none are open to participants now.
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The study population will include adults aged 18 years or older with occupational injuries recognized by the National Insurance Institute between January 1, 2020, and December 31, 2024. Eligible records will be selected from the national occupational-injury administrative database and assigned to one of seven predefined geographic-climatic regions according to the workplace or accident location. Environmental exposure will be determined by linking each injury date, time, and location to the nearest representative meteorological monitoring station. The study will include workplace, occupational-traffic, and commuting injuries meeting the prespecified eligibility criteria.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
For time-specific analyses, a valid recorded accident time permitting linkage to the closest preceding three-hour meteorological observation.
Exclusion Criteria:
Occupational injuries occurring in the northern valleys and inland northern region will be assigned to this geographic-climatic division according to the location of the workplace or accident. Meteorological exposure will be determined using data from the nearest representative monitoring station, including Dafna, Tavor Kadoorie, or Nazareth. This region is characterized by inland climatic conditions with substantial seasonal variation in temperature and humidity. Accident occurrence and severity will be evaluated in relation to temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.
Other: Ambient Weather Exposure
Occupational injuries occurring along the northern Mediterranean coastal region will be assigned to this geographic-climatic division according to the location of the workplace or accident. Meteorological exposure will be determined using data from the Haifa Technion monitoring station or the nearest available representative station. This region is characterized by a Mediterranean coastal climate, with relatively high humidity, moderate winter temperatures, warm summers, and frequent sea-breeze effects. Accident occurrence and severity will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.
Other: Ambient Weather Exposure
Occupational injuries occurring within the central Mediterranean coastal region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Tel Aviv Coast monitoring station or the nearest available representative station. This region is characterized by a warm Mediterranean climate, relatively high humidity, mild winters, hot summers, and frequent sea-breeze effects. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.
Other: Ambient Weather Exposure
Occupational injuries occurring within the southern Mediterranean coastal region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Ashqelon Port monitoring station or the nearest available representative station. This region is characterized by a warm coastal Mediterranean climate, relatively high humidity, mild winters, hot summers, and frequent sea-breeze effects. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.
Other: Ambient Weather Exposure
Occupational injuries occurring within the central highlands region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Jerusalem Centre monitoring station or the nearest available representative station. This region is characterized by higher elevation, lower average humidity than the coastal areas, greater day-night temperature variation, cooler winters, and warm, dry summers. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.
Other: Ambient Weather Exposure
Occupational injuries occurring within the Negev desert region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Avdat monitoring station or the nearest available representative station. This region is characterized by an arid desert climate, very low relative humidity, intense solar exposure, high daytime temperatures, substantial day-night temperature variation, and limited rainfall. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, wind speed, extreme heat, extreme cold, and other predefined environmental indicators.
Other: Ambient Weather Exposure
Occupational injuries occurring within the Dead Sea and extreme arid region will be assigned to this geographic-climatic division according to the workplace or accident location. Meteorological exposure will be determined using data from the Massada monitoring station or the nearest available representative station. This region is characterized by very low elevation, an extremely hot and arid climate, low annual rainfall, intense solar radiation, prolonged periods of extreme heat, and substantial seasonal temperature variation. The occurrence and severity of occupational injuries will be evaluated in relation to ambient temperature, relative humidity, extreme heat, extreme cold, and other predefined environmental indicators. Wind speed will be analyzed when reliable measurements are available.
Other: Ambient Weather Exposure
Ambient temperature, relative humidity, and wind speed at the occupational-injury location and time will be retrospectively obtained from the nearest representative meteorological monitoring station. Environmental exposures will be analyzed in relation to occupational-injury occurrence and severity.
Occurrence of Recognized Occupational Injury During Case Versus Matched Control Periods
The number of accepted occupational-injury events occurring during predefined case periods will be evaluated in relation to ambient temperature, relative humidity, and wind speed obtained from the nearest representative meteorological station. Each injury period will be compared with control periods matched by geographic-climatic region, calendar year and month, day of the week, and three-hour time interval. The association between environmental exposure and occupational-injury occurrence will be estimated using time-stratified case-crossover analysis with conditional logistic regression.
Time frame: At the index injury date and matched control dates, January 1, 2020-December 31, 2024.
Plan to share: No — Individual participant data will not be publicly shared because the study uses confidential administrative records owned and controlled by the National Insurance Institute. Access is restricted to authorized researchers within a secure research environment and is governed by institutional confidentiality agreements, data-protection requirements, and applicable privacy legislation. The combination of accident dates, geographic information, occupational characteristics, and disability outcomes may create a residual risk of participant re-identification even after removal of direct identifiers. Only aggregated, disclosure-controlled results approved by the data custodian may be reported or published.
Ran from Jan 2020 to primary completion in Dec 2024, 59 months.
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This study is active, not recruiting, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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