An interventional study of Medication Collaboration Intervention in Dementia Family Caregiver, Dementia and Medication Adherence, sponsored by Northwestern University. Recruiting at 1 site in United States. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2026-08-14.
Sponsored by Northwestern University · Not applicable, Interventional, and Supportive care
This study examines the feasibility and acceptability of a brief medication collaboration intervention among older adults (age 60+) with early-stage dementia or mild cognitive impairment who take multiple medications and their family caregivers. The main aims are to: 1) determine the feasibility and acceptability of the intervention for older adults with early-stage dementia and their family caregivers, and 2) explore the effects of intervention on medication collaboration, medication adherence, and beliefs about dementia and autonomy.
In this study, participants will: 1) complete a 15-30-minute baseline interview (by Zoom or phone), 2) participate together in a 45-60-minute virtual intervention led by an interventionist that includes:
Assessment of medication responsibilities and beliefs. Education about dementia and medication management. Cognitive restructuring to address beliefs about independence and caregiver assistance.
Collaborative planning for medication responsibilities and routines; and lastly 3) complete a 15-20-minute one-month follow-up interview (by Zoom or phone) to assess the intervention's acceptability and changes in medication management outcomes.
2,372 studies on the registry are indexed under Dementia; 574 are open to participants now.
This study's planned enrollment of 30 is below the median of 90 across 1,758 interventional studies indexed under Dementia.
Browse Dementia studies →Northwestern University is the lead sponsor of 1,423 studies on the registry; 198 are open to participants now.
Of its 105 completed or terminated interventional studies of FDA-regulated products, 78 (74%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Inclusion criteria for caregivers include::
Exclusion Criteria:
Participants receive a brief virtual medication collaboration intervention designed to support collaborative medication management among older adults with early-stage dementia and their family caregivers. The intervention includes an assessment of medication responsibilities and beliefs, dementia and medication management education, reframing beliefs about autonomy and caregiver assistance, and collaborative development of medication management plans and action planning by setting implementation intentions.
Behavioral: Medication Collaboration Intervention
A brief virtual behavioral intervention for older adults with early-stage dementia and their family caregivers designed to support collaborative medication management. The intervention includes: (1) assessment of beliefs about dementia, autonomy, and current medication responsibilities; (2) education on dementia progression and medication management; (3) reframing maladaptive beliefs regarding independence and caregiver assistance; and (4) collaborative development of implementation intentions and medication responsibility plans to facilitate medication adherence and the transition of medication management responsibilities. The intervention is delivered remotely via Zoom or telephone in a single 45-60-minute session by trained study interventionists.
Acceptability of the Medication Collaboration Intervention
Participant-reported acceptability of the intervention will be measured using The Acceptability of Intervention Measure, Intervention Appropriateness Measure, and Feasibility of Intervention Measure. Scale values range from 1 to 5 with a higher score indicating greater perceived acceptability of the Medication Collaboration Intervention.
Time frame: 1 Month
Medication Collaboration
Self-report of caregiver involvement with medications will be measured using an adapted version of the dyadic relationship scale. Scale scores range from 1-5 with a higher score indicating higher medication collaboration between caregiver and patient.
Time frame: 1 Month
Medication adherence
Self-reported medication adherence via the Medication Adherence Scale. Responses are summed and averaged, with total scores ranging from 0-5, and higher scores indicating better adherence.
Time frame: 1 Month
Beliefs about dementia
Beliefs about dementia will be measured using the Representations and Adjustment to Dementia Index (RADIX) questionnaire. Individual items are scored, and scores range from 1-4.
Time frame: 1 month
Medication Administration Hassles
Caregiver reported medication administration hassles will be measured using The Family Caregiver Medication Administration Hassles Scale. We will use the Logistics subscale. The total score ranges from 0-35, with higher scores indicating greater perceived hassle associated with managing the logistics of another person's medication regimen
Time frame: 1 Month
Beliefs about independence with medicines
Beliefs about independence with medicines will be self reported using individual items. We will use report the frequency of agreement with individual items, where greater agreements indicates stronger beliefs in the importance of medication autonomy and independence.
Time frame: 1 month
Plan to share: No
No publications or documents are linked to this record.
Started Aug 2026 (actual). Primary completion is estimated for Dec 2026, 4 months after the start.
Of 855 non-industry interventional studies with no phase under Dementia, half reached primary completion within 25 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 44. This study's planned 4 months is below that.
Counting every sponsor, half of 901 studies reached it within 25 months; a quarter within 11 and three quarters within 43.
How these figures are worked out, and which studies are left out of them.
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