An observational study in Wrinkles and Rhytides, sponsored by Alma Mater Europaea College of Medical Sciences "Rezonanca". Completed at 1 site in Kosovo. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-31.
Sponsored by Alma Mater Europaea College of Medical Sciences "Rezonanca" · Observational
This is a retrospective data collection from patients treated with the bipolar radiofrequency applicator (Coaxipolar) of the Accent devices. Patient files were screened for suitable candidates providing before and after treatment pictures for blinded evaluation. The safety and efficacy of bipolar RF technology, both as a standalone treatment and in combination with unipolar RF, for facial contouring and the reduction of wrinkles and fine lines is investigated.
This is the only study on the registry with Alma Mater Europaea College of Medical Sciences "Rezonanca" as lead sponsor.
Counted across the registry records on this site, refreshed daily.
A total of up to 150 adult subjects of both genders and all skin types are to be included if they meet all of the inclusion and none of the exclusion criteria. Investigator is collecting data retrospectively from their respective patient pool.
Inclusion Criteria:
Exclusion Criteria:
GAIS
Skin laxity was assessed using the Global Aesthetic Improvement Scale (GAIS; 0-4 scale), GAIS 5-point scale (0 = worse, 1 = no change, 2 = mild improvement, 3 = much improvement, 4 = very much improvement)
Time frame: From enrollment to the end of treatment at 24 weeks
Fitzpatrick-wrinkle-scale
Wrinkle severity was assessed by the same three blinded evaluators using the MFWS with seven graded classes ranging from Class 0 (no wrinkles) to Class 3 (deep wrinkles) based on estimated wrinkle depth
Time frame: From enrollment to the end of treatment at 24 weeks
VISIA Score Change (if applicable)
The VISIA® Complexion Analysis Camera (Canfield Scientific, USA) captures standardized images to quantify wrinkle features using absolute scores, which measure the size, area, and intensity of skin features. Changes from baseline are calculated as the average of bilateral measurements, where negative change scores indicate clinical improvement.
Time frame: From enrollment to the end of treatment at 24 weeks
Patient satisfaction (if applicable)
Self-reported on a 5-point Likert scale (0 = worse, 1 = no change, 2 = satisfied, 3 = much satisfied, 4 = very much satisfied)
Time frame: From enrollment to the end of treatment at 24 weeks
This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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Cutis Laxa