An interventional study of PCA in Arthroplasty and Knee Osteoarthritis, sponsored by Bursa Yuksek Ihtisas Training and Research Hospital. Not yet recruiting. Open to participants aged 45 Years to 100 Years. Per ClinicalTrials.gov, last updated 2026-08-03.
Sponsored by Bursa Yuksek Ihtisas Training and Research Hospital · Not applicable, Interventional, and Treatment
This study evaluates the analgesic efficacy and motor-sparing properties of ultrasound-guided Suprainguinal Fascia Iliaca Block (S-FIB) compared with Adductor Canal Block (ACB) in patients undergoing primary total knee arthroplasty (TKA). The main hypothesis is that ACB better preserves quadriceps muscle strength, allowing earlier functional mobilization, while providing comparable (non-inferior) analgesia to S-FIB.
Total knee arthroplasty is associated with severe postoperative pain requiring effective multimodal analgesia, and regional nerve blocks are integral to Fast-Track / ERAS (Enhanced Recovery After Surgery ) protocols. The Suprainguinal Fascia Iliaca Block (S-FIB) targets the anterior branches of the lumbar plexus (femoral, lateral femoral cutaneous, and obturator nerves) from a single high-volume injection, but proximal femoral spread can produce quadriceps motor weakness. The Adductor Canal Block (ACB) predominantly blocks the saphenous nerve, sparing motor function at the potential expense of less comprehensive analgesia.
3,302 studies on the registry are indexed under Osteoarthritis, Knee; 608 are open to participants now.
This study's planned enrollment of 60 is below the median of 70 across 2,731 interventional studies indexed under Osteoarthritis, Knee.
Browse Osteoarthritis, Knee studies →Bursa Yuksek Ihtisas Training and Research Hospital is the lead sponsor of 45 studies on the registry; 18 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Active ultrasound-guided Suprainguinal Fascia Iliaca Block
Drug: PCA
Active ultrasound-guided Adductor Canal Block
Drug: PCA
All patients receive standardized spinal anesthesia and postoperative intravenous PCA tramadol within a standardized multimodal regimen.
Postoperative Pain Intensity (NRS)
Numerical Rating Scale (0-10) at rest and during active knee flexion (30°). Time Frame: Postoperative hours 2, 6, 12, 24, and 48.
Time frame: Postoperative hours 24 hour
Quadriceps Muscle Strength
Active Straight Leg Raise (SLR) Angle Maximum hip flexion angle (degrees, 0-90°) achieved during an active straight leg raise in the supine position, measured with a digital clinometer/goniometer.
Time frame: Postoperative hours 6 and 12.
Cumulative Opioid Consumption
Total IV tramadol delivered via PCA (patient controlled analgesia).
Time frame: 24 and 48 hours postoperatively.
Time to First Mobilization
Hours from end of surgery to first assisted/unassisted ambulation
Time frame: Up to 48 hours postoperatively.
Quality of Recovery (QoR-15)
Validated 15-item questionnaire (0-150; higher = better recovery).
Time frame: Baseline (preoperative) and 24 hours postoperatively.
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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Bursa Yuksek Ihtisas Training and Research Hospital