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RecruitingNCT07726810DNSUpdated Aug 12, 2026

Dynamic Neuromuscular Stability Exercises With and Without Rhythmic Auditory Stimulation in Lateral Ankle Sprain

An interventional study of Dynamic Neuromuscular Stabilization with Rhythmic Auditory Stimulation and Dynamic Neuromuscular Stabilization Alone in Ankle Sprain, Lateral Ankle Sprain and Lateral Ankle Instability, sponsored by Riphah International University. Recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 30 Years. Per ClinicalTrials.gov, last updated 2026-08-12.

Sponsored by Riphah International University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Started Jul 2026; still recruiting 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
44
Allocation
Randomized
Ages
18 Years to 30 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 10 studies in Ankle Injuries by Riphah International University — 3 open to participants now, 3 under way, none of them phase 3. Ankle Injuries · Riphah International University.

Started
2026
with 1 other
No phase
9 of 10
3 open now
Registered
9th of 10
by date

Among the 10 studies in Ankle Injuries by Riphah International University, this one is one of 2 that started in 2026, is one of 9 with no phase, and was the 9th registered.

By phase

10 studies; the count open now beside each. This study's row is marked.

No phasethis study9 · 3 open
Other kind1 · 0 open

By the year they started

First in 2021; this study’s year is marked. 2 started in 2026.

Size and results

Median enrollment 38 across the 9 interventional studies, 125 across the 1 observational. Of the 5 that completed or were terminated, 0 (0%) have results posted.

Watch this landscapeDownload CSVWith an account: a weekly mail of what changed among 10 studies in Ankle Injuries by Riphah International University, or all of them as a file.
02

Study summary

To examine the effects of Dynamic Neuromuscular Stability exercises with and without Rhythmic Auditory Stimulation on balance, proprioception, and functional performance in badminton players with lateral ankle sprain.

Read the detailed description

A randomized controlled trial compared Dynamic Neuromuscular Stabilization (DNS), balance training, and conventional rehabilitation in amateur athletes with chronic ankle sprain. The findings demonstrated that both DNS and balance training significantly improved ankle stability, balance, reaction time, and functional performance, highlighting their effectiveness in rehabilitation.

A quasi-experimental study investigated the effects of ankle proprioceptive training in recreational badminton players with pronated feet. The intervention resulted in significant improvements in agility, dynamic balance, and ankle function compared with conventional training.

Another study evaluated neuromuscular training with and without kinesio taping in football players following ankle sprain. Both interventions effectively reduced pain and improved range of motion, balance, and functional performance, while the addition of kinesio taping produced greater clinical benefits.

A randomized study assessed the effectiveness of a six-week neuromuscular training program in individuals with lateral ankle sprain. The intervention significantly enhanced muscle strength, proprioception, balance, range of motion, and overall functional recovery compared with routine training.

A pilot randomized trial examined rhythmic auditory stimulation-based gait training in older adults undergoing rehabilitation. The intervention significantly improved gait speed and demonstrated its feasibility as an effective rehabilitation strategy.

A randomized controlled trial evaluated the effects of Dynamic Neuromuscular Stabilization on functional movement. The results showed that DNS training produced significant improvements in movement quality and functional performance compared with conventional physical fitness exercises.

03

Conditions studied

  • Ankle Sprain
  • Lateral Ankle Sprain
  • Lateral Ankle Instability
  • Dynamic Neuromuscular Stabilization (DNS)
  • Balance
  • Proprioception

Browse trials for

Keywords

  • Rhythmic Auditory Stimulation
04

Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age 18-30 years
  • Both male and female genders
  • Diagnosed with Grade I or II lateral ankle sprain (subacute to chronic phase)
  • Within 2-8 weeks post-injury

Exclusion criteria

Exclusion Criteria:

  • History of ankle surgery
  • Vestibular, neurological, or hearing disorders
  • Acute pain prevents participation
  • Current involvement in other rehab programs
  • Any fracture or other injury
  • Any systemic illness
  • Any inflammatory disease (Rheumatoid arthritis, gout)
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
44 participants (estimated)

Study arms

  • Experimental
    Dynamic Neuromuscular Stabilization with Rhythmic Auditory Stimulation

    The intervention was progressively advanced over six weeks. Baseline treatment included warm-up exercises, stretching, and basic balance training with rhythmic auditory cues. During Week 2, participants performed DNS breathing and core stabilization exercises, proprioceptive training, and Theraband ankle strengthening. In Week 4, advanced DNS postures, dynamic balance, and functional movement exercises were introduced with increased rhythmic cueing. By Week 6, participants progressed to advanced DNS exercises, unilateral balance and hopping drills, agility training, and badminton-specific movements synchronized with rhythmic auditory stimulation to enhance neuromuscular control and functional performance.

    Other: Dynamic Neuromuscular Stabilization with Rhythmic Auditory Stimulation

  • Active comparator
    Dynamic Neuromuscular Stabilization Alone

    The intervention was progressively advanced over six weeks. Baseline treatment included warm-up exercises, stretching, and basic balance training. During Week 2, participants performed DNS breathing and core stabilization exercises, proprioceptive training, and Theraband ankle strengthening. In Week 4, advanced DNS postures, dynamic balance, and functional movement exercises were introduced. By Week 6, participants progressed to advanced DNS exercises, unilateral balance and hopping drills, agility training, and badminton-specific movements to enhance neuromuscular control, balance, and functional performance.

    Other: Dynamic Neuromuscular Stabilization Alone

Interventions

  • OtherDynamic Neuromuscular Stabilization with Rhythmic Auditory Stimulation

    The intervention was progressively advanced over six weeks. Baseline treatment included warm-up exercises, stretching, and basic balance training with rhythmic auditory cues. During Week 2, participants performed DNS breathing and core stabilization exercises, proprioceptive training, and Theraband ankle strengthening. In Week 4, advanced DNS postures, dynamic balance, and functional movement exercises were introduced with increased rhythmic cueing. By Week 6, participants progressed to advanced DNS exercises, unilateral balance and hopping drills, agility training, and badminton-specific movements synchronized with rhythmic auditory stimulation to enhance neuromuscular control and functional performance.

    Also known as: DNS, RAS

  • OtherDynamic Neuromuscular Stabilization Alone

    The intervention was progressively advanced over six weeks. Baseline treatment included warm-up exercises, stretching, and basic balance training. During Week 2, participants performed DNS breathing and core stabilization exercises, proprioceptive training, and Theraband ankle strengthening. In Week 4, advanced DNS postures, dynamic balance, and functional movement exercises were introduced. By Week 6, participants progressed to advanced DNS exercises, unilateral balance and hopping drills, agility training, and badminton-specific movements to enhance neuromuscular control, balance, and functional performance.

    Also known as: DNS

06

What researchers measure

Primary outcomes

  1. Joint Position Sense Test

    It evaluates proprioception by measuring a subject's ability to actively or passively reproduce a joint angle without visual input. It has shown moderate to high reliability (ICC = 0.70-0.93) and is a valid measure of sensorimotor deficits following lateral ankle injuries. Pre and post assessment will be done.

    Time frame: 6 weeks

  2. Star Excursion Balance Test

    It is a dynamic balance test that assesses neuromuscular control and postural stability during multi-directional reaching tasks while standing on one leg. It demonstrates high reliability (ICC = 0.85-0.96) and good validity in identifying lower limb deficits, especially following ankle sprains and in athletic populations. Pre and post assessment will be done.

    Time frame: 6 weeks

  3. Sports Ankle Rating Scale

    The Sports Ankle Rating Scale is a subjective questionnaire designed to assess functional limitations, pain, and instability related to ankle injuries in athletic populations. It demonstrates good reliability (Cronbach's alpha \> 0.80) and acceptable validity when compared with clinical outcomes. The scale includes sections on pain, function during sports, and instability episodes to provide a comprehensive ankle health profile. Pre and post assessment will be done.

    Time frame: 6 weeks

07

Study locations

1 of 1 sites recruiting
  • Sports Board of Punjab
    Lahore, Punjab Province 54000, Pakistan
    Recruiting
08

References and documents

Publications

  • Igusa T, Kobayashi T, Uchida H, Tsuchiya K, Akiba T, Sema S, Kaneko S, Yoshita T, Nagai S, Tanaka Y, Kikuchi S, Hirao K. Effect of gait training using rhythmic auditory stimulation on gait speed in older adults admitted to convalescent rehabilitation wards: A study protocol for a pilot randomized controlled clinical trial. Contemp Clin Trials Commun. 2023 Apr 1;33:101125. doi: 10.1016/j.conctc.2023.101125. eCollection 2023 Jun. PubMed 37091510 ↗
  • Karami M, Jamehbozorgi A, Salemi P, Rezaei M. The Effect of 6 Weeks Neuromuscular Training On Muscle Strength, Balance, Range of Motion & Proprioception In Males With Lateral Ankle Sprain. Journal of Modern Rehabilitation. 2025.
  • Yesilkir S, Sahin GE. Dynamic neuromuscular stabilization training for chronic ankle instability: A randomized controlled trial in amateur athletes. J Back Musculoskelet Rehabil. 2026 Jul;39(4):1157-1169. doi: 10.1177/10538127251338170. Epub 2025 May 11. PubMed 40350619 ↗
  • Meng L, Wang Y, Wang Z, Liu Y, Tan Y, Zhang Y, Wei X, Mao X, Zhang Q. Effects of auditory rhythmic adaptation on lower limb joint mechanics during single-leg drop landings in individuals with functional ankle instability. Front Hum Neurosci. 2025 Jul 2;19:1579260. doi: 10.3389/fnhum.2025.1579260. eCollection 2025. PubMed 40672743 ↗
  • Mansouri M, Saki F. The Effectiveness of Neuromuscular Training With and Without Cognitive Intervention on Dynamic Balance and Proprioception of Female Athletes Prone to Ankle Sprain Injury: A Randomized Control Trial.
  • Kim KM, Kim JS, Needle AR. Soleus arthrogenic muscle inhibition following acute lateral ankle sprain correlates with symptoms and ankle disability but not with postural control. J Sport Health Sci. 2024 Jul;13(4):559-568. doi: 10.1016/j.jshs.2024.02.005. Epub 2024 Feb 28. PubMed 38428732 ↗
  • Mansur H, Durigan JLQ, Contessoto S, Maranho DA, Nogueira-Barbosa MH. Evaluation of the Healing Status of Lateral Ankle Ligaments 6 Weeks After an Acute Ankle Sprain. J Foot Ankle Surg. 2024 Nov-Dec;63(6):637-645. doi: 10.1053/j.jfas.2024.07.004. Epub 2024 Jul 25. PubMed 39067610 ↗
  • Taketomi S, Kawaguchi K, Mizutani Y, Takei S, Yamagami R, Kono K, Murakami R, Kage T, Arakawa T, Fujiwara S, Tanaka S, Ogata T. Factors Associated With a Lateral Ankle Sprain in Young Female Soccer Players: A Prospective Cohort Study. Orthop J Sports Med. 2024 Feb 26;12(2):23259671231221481. doi: 10.1177/23259671231221481. eCollection 2024 Feb. PubMed 38410169 ↗
  • Liu Z, Yamaguchi R, Fu S, Zhao H, Li Y, Kobayashi Y, Gong Y, Kumai T. Epidemiology of ankle sprain and chronic ankle instability in elite adolescent dancesport athletes. Phys Sportsmed. 2025 Apr;53(2):119-128. doi: 10.1080/00913847.2024.2418283. Epub 2024 Oct 20. PubMed 39412831 ↗
  • Wagemans J, Dingenen B, Clockaerts S, Bleakley C. Physiotherapists Approach in Lateral Ankle Sprain Rehabilitation: A Survey Study. J Sport Rehabil. 2025 Apr 4;35(1):31-38. doi: 10.1123/jsr.2024-0442. Print 2026 Jan 1. PubMed 40174890 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 12, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07726810
Responsible party
Sponsor
First posted
Jul 24, 2026
Start date
Jul 14, 2026
Primary completion
Aug 14, 2026 (estimated)
Completion
Sep 1, 2026 (estimated)
Last update
Aug 12, 2026

Study contacts

Imran Amjad, PhD
Contact
imran.amjad@riphah.edu.pk
03324390125
Sidra Shafique, MS
principal investigator · Riphah International University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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