An interventional study of Open appendectomy and Laparoscopic appendectomy in Bowel Obstruction, sponsored by Sohag University. Completed at 1 site in Egypt. Open to participants aged 12 Years and older. Per ClinicalTrials.gov, last updated 2026-07-21.
Sponsored by Sohag University · Not applicable, Interventional, and Diagnostic
Acute appendicitis is one of the most common causes of acute abdominal pain requiring surgical intervention, with appendectomy being the definitive treatment . Traditionally performed through an open approach, appendectomy has evolved significantly with the advent of minimally invasive surgery. Since its introduction in the late 1980s, laparoscopic appendectomy has gained widespread acceptance and is now often preferred due to its well-documented advantages, including reduced postoperative pain, shorter hospital stay, quicker return to normal activity, and improved cosmetic outcomes . Despite these benefits, concerns remain regarding the long-term postoperative complications associated with both laparoscopic and open approaches, one of the most clinically significant being bowel obstruction
Postoperative bowel obstruction, often resulting from intra-abdominal adhesions, is a common and sometimes serious complication following abdominal surgeries. The pathogenesis of these adhesions can be influenced by several factors, including the extent of tissue handling, exposure of peritoneal surfaces, the degree of inflammation presents during surgery, and the surgical technique used .
Open surgery, by its nature, involves a larger incision and greater manipulation of intra-abdominal structures, which may predispose patients to more extensive adhesion formation and, subsequently, higher rates of bowel obstruction. On the other hand, laparoscopic surgery, with its minimal access approach, is associated with less tissue trauma and reduced adhesion formation in various abdominal procedures. However, it is not entirely devoid of risk, and rare but serious complications such as internal herniation and port site adhesions can also lead to bowel obstruction in laparoscopic cases .
The clinical presentation of postoperative bowel obstruction can vary widely, ranging from mild intermittent symptoms to complete mechanical obstruction requiring urgent reoperation. Understanding the relative risk and nature of bowel obstruction following laparoscopic versus open appendectomy is essential for both surgical decision-making and informed patient counseling. Moreover, identifying differences in the timing, severity, and management outcomes of this complication between the two surgical approaches may help refine perioperative strategies to minimize patient morbidity .
While several studies have attempted to compare postoperative outcomes between laparoscopic and open appendectomy, data specifically focusing on the incidence and characteristics of bowel obstruction are less abundant and sometimes conflicting . Some retrospective reviews suggest a lower incidence of bowel obstruction following laparoscopic appendectomy, while others report no significant difference. Variations in surgical technique, patient selection, underlying pathology, and follow-up duration may all contribute to these discrepancies .
104 studies on the registry are indexed under Intestinal Obstruction; 15 are open to participants now.
This study's enrollment of 50 is below the median of 62 across 54 interventional studies indexed under Intestinal Obstruction.
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Exclusion Criteria:
Procedure: Open appendectomy
Procedure: Laparoscopic appendectomy
Open appendectomy For gruop A
Laparoscopic appendectomy for group B
Incidence of bowel obstruction post laparoscopic versus open appendectomy
Time frame: 6 months
• Operative time
Time frame: : During operation (from incision to closure)
Analgesic requirement
Time frame: From postoperative Day 0 through postoperative Day 7.
Postoperative pain
Postoperative pain assessed using the Visual Analog Scale (VAS; range 0-10, where 0 indicates no pain and 10 indicates the worst imaginable pain).
Time frame: Postoperative Day 1.
Post operative hospital stay
Time frame: From the day of surgery until hospital discharge (average of 2-5 days).
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: Undecided
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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