ClinicalTrials.gg
CompletedNCT07710924Updated Jul 17, 2026

Effects of Shockwave Therapy Versus Ultrasound Therapy Among Patients With Chronic Sciatica

An interventional study of Extracorporeal Shockwave Therapy and Therapeutic Ultrasound in Sciatica, Chronic Sciatica and Lumbar Radiculopathy, sponsored by University of Lahore. Completed at 1 site in Pakistan. Open to participants aged 20 Years to 45 Years. Per ClinicalTrials.gov, last updated 2026-07-17.

Sponsored by University of Lahore · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Registered 1 year after the study started (first participant enrolled Jun 2025, registered Jul 2026).
Phase
Not applicable
Study type
Interventional
Enrollment
66
Allocation
Randomized
Ages
20 Years to 45 Years
Sex
All
01

Study summary

Sciatica is characterized by radiating pain, functional limitations, reduced flexibility, disturbed sleep, and impaired quality of life. Extracorporeal Shockwave Therapy (ESWT) and Therapeutic Ultrasound are commonly used physiotherapy modalities for pain relief and tissue healing; however, evidence directly comparing their effectiveness remains limited. This randomized controlled trial compares the effects of Shockwave Therapy and Ultrasound Therapy, each combined with conventional physiotherapy, on pain intensity, hamstring range of motion, sleep quality, and quality of life in patients with chronic sciatica.

Read the detailed description

This randomized controlled trial compares two physiotherapy interventions for chronic sciatica. Sixty-six participants will be randomly allocated to either Shockwave Therapy plus Conventional Physiotherapy or Ultrasound Therapy plus Conventional Physiotherapy. Both groups will receive identical conventional physiotherapy consisting of heat therapy, myofascial release, stretching, and strengthening exercises. Treatment will be administered four sessions per week for eight weeks. Outcomes including pain intensity, hamstring range of motion, sleep quality, and quality of life will be measured at baseline, Week 4, and Week 8 by a blinded outcome assessor.

02

Conditions studied

  • Sciatica
  • Chronic Sciatica
  • Lumbar Radiculopathy

Keywords

  • Sciatica
  • Chronic Sciatica
  • Lumbar Radiculopathy
  • Shockwave Therapy
  • Extracorporeal Shockwave Therapy
03

In context

Sciatica

149 studies on the registry are indexed under Sciatica; 31 are open to participants now.

This study's enrollment of 66 is close to the median of 68 across 122 interventional studies indexed under Sciatica.

Browse Sciatica studies →

Lead sponsor

University of Lahore is the lead sponsor of 232 studies on the registry; 41 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adults aged 20-45 years.
  • Clinically diagnosed chronic sciatica.
  • Radiating pain below the knee.
  • Positive Straight Leg Raise test (30°-70°).
  • Pain intensity ≥4/10 on the Numeric Pain Rating Scale.
  • Symptoms persisting for at least 3 months.
  • Presence of tingling, numbness, lumbar radiculopathy, or piriformis syndrome.

Exclusion criteria

Exclusion Criteria:

  • Lumbar disc herniation.
  • Progressive neurological disorders.
  • Ankylosing spondylitis.
  • Paget disease.
  • Tuberculosis.
  • .
  • Rheumatoid arthritis or other inflammatory disorders.
  • Previous spinal surgery or fracture.
  • Fever, unexplained weight loss, or systemic illness.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
66 participants (actual)

Study arms

  • Experimental
    Shockwave Therapy + Conventional Physiotherapy

    Participants will receive radial extracorporeal shockwave therapy in addition to standardized conventional physiotherapy four times per week for eight weeks.

    Device: Extracorporeal Shockwave Therapy · Other: Conventional Physiotherapy

  • Active comparator
    Ultrasound Therapy + Conventional Physiotherapy

    Participants will receive therapeutic ultrasound in addition to standardized conventional physiotherapy four times per week for eight weeks.

    Device: Therapeutic Ultrasound · Other: Conventional Physiotherapy

Interventions

  • DeviceExtracorporeal Shockwave Therapy

    Radial extracorporeal shockwave therapy will be applied to the sciatic nerve origin and piriformis region using standardized treatment parameters for approximately 10 minutes during each treatment session.

    Also known as: ESWT, Radial Shockwave Therapy

  • DeviceTherapeutic Ultrasound

    Therapeutic ultrasound will be applied to the gluteal and lumbar regions using standardized frequency and intensity parameters for approximately 10 minutes during each treatment session.

    Also known as: Ultrasound Therapy, Ultrasound

  • OtherConventional Physiotherapy

    Conventional physiotherapy will include moist heat therapy, myofascial release, stretching exercises, and strengthening exercises administered during every treatment session.

06

What researchers measure

Primary outcomes

  1. Pain Intensity

    Numeric Pain Rating Scale (0-10). Higher scores indicate greater pain.

    Time frame: Baseline, Week 4, Week 8

  2. Hamstring Range of Motion

    Hip flexion measured with a universal goniometer during the Straight Leg Raise test.

    Time frame: Baseline, Week 4, Week 8

Secondary outcomes

  1. Sleep Quality

    Sleep Quality Scale. Higher scores indicate poorer sleep quality.

    Time frame: Baseline, Week 4, Week 8

07

Study locations

1 site
  • ULTH
    Lahore, Pakistan
08

References and documents

Individual participant data

Plan to share: No — Individual participant data will not be shared because this study was conducted as an academic research project. The informed consent obtained from participants did not include provisions for public data sharing, and the dataset contains sensitive personal health information. Data will be stored securely and used only for academic and research purposes in accordance with institutional ethics approval.

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jun 2025 to primary completion in Mar 2026, 8 months.

Of 44 non-industry interventional studies with no phase under Sciatica, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 6 and three quarters within 30. This study's 8 months is below that.

Counting every sponsor, half of 44 studies reached it within 11 months; a quarter within 6 and three quarters within 30.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 14, 2026
First posted
Jul 17, 2026
StartActual
Jun 30, 2025
Primary completionActual
Mar 10, 2026
CompletionActual
Apr 12, 2026
Last update
Jul 17, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 17, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07710924
Responsible party
Rimsha Imtiaz (Doctor of Physical Therapy Student, University of Lahore) — Principal investigator
First posted
Jul 17, 2026
Start date
Jun 30, 2025
Primary completion
Mar 10, 2026
Completion
Apr 12, 2026
Last update
Jul 17, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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