ClinicalTrials.gg
Not yet recruitingNCT07708415Updated Jul 16, 2026

The Correlation of Postoperative Polyp Recurrence and Colorectal Cancer

An observational study in Colorectal Cancer and Polyps, sponsored by Gansu Provincial Hospital. Not yet recruiting at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2026-07-16.

Sponsored by Gansu Provincial Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
3,000
Ages
18 Years to 80 Years
Sex
All
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Study summary

Postoperative endoscopic polyp recurrence correlation of colorectal cancer: a retrospective cohort open-label study

Read the detailed description

This study aims to address the gaps in existing research by focusing on the high-risk group of colorectal cancer patients post-radical surgery, systematically reviewing potential factors influencing polyp recurrence, further clarifying independent risk factors for postoperative polyp recurrence in this population, and constructing a predictive model that better aligns with the clinical needs of such patients, thereby providing more precise references for developing personalized follow-up strategies in clinical practice.

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Conditions studied

  • Colorectal Cancer
  • Polyps

Keywords

  • Colorectal Cancer
  • Polyp recurrence
  • Pathomics
  • Prognostic model
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In context

Colorectal Neoplasms

6,541 studies on the registry are indexed under Colorectal Neoplasms; 1,667 are open to participants now.

This study's planned enrollment of 3,000 is above the median of 250 across 1,440 observational studies indexed under Colorectal Neoplasms.

Browse Colorectal Neoplasms studies →

Lead sponsor

Gansu Provincial Hospital is the lead sponsor of 4 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients who underwent radical surgery for colon cancer at Gansu Provincial People's Hospital from January 2015 to December 2024 and regularly completed colonoscopy follow-up after surgery were selected as the research subjects.After the completion of the prediction model construction, we will include 3-5 external queues for external validation.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Patients who underwent radical surgery for colon cancer at Gansu Provincial People's Hospital from January 2015 to December 2024 and regularly completed colonoscopy follow-up after surgery were selected as the research subjects. Inclusion criteria:

Diagnosed with colon cancer through histopathological examination ; Undergoing radical R0 resection ; Complete Colonoscopy follow-up after surgery less than 12 months.

Exclusion criteria

Exclusion Criteria:

With adenomatous polyposis , Lynch syndrome and Peutz-Jeghers syndrome; Combined inflammatory bowel disease; Polyp were present before surgery and have not been completely removed; With distant or local recurrence; Clinical data is missing and can not be analyzed.

Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Metastases

Cancer that has spread from where it began to other parts of the body. “Metastatic” cancer is cancer that has spread this way.

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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
3,000 participants (estimated)
Patient registry
No

Groups and cohorts

  • Postoperative endoscopic polyp recurrence of colorectal cancer

    Corhort of colorectal cancer patients undergoing colonoscopy follow-up after surgery

    Procedure: Endoscopic polypectomy

Interventions

  • ProcedureEndoscopic polypectomy

    Endoscopic polypectomy

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What researchers measure

Primary outcomes

  1. Adenoma recurrence after colorectal surgery

    Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence

    Time frame: Postoperative;follow up till 5 years

  2. Colitisafter colorectal surgery

    Postoperative colonoscopy review of colorectal cancer patients reveals adenoma recurrence

    Time frame: Postoperative;follow up till 5 years

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Study locations

1 site
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References and documents

Publications

  • Galjart B, Hoppener DJ, Aerts JGJV, Bangma CH, Verhoef C, Grunhagen DJ. Follow-up strategy and survival for five common cancers: A meta-analysis. Eur J Cancer. 2022 Oct;174:185-199. doi: 10.1016/j.ejca.2022.07.025. Epub 2022 Aug 27. PubMed 36037595 ↗
  • IJspeert JEG, Bretthauer M, Jover R, Dekker E; Dutch colonoscopy surveillance working group. Balancing benefit and burden: rethinking post-polypectomy colonoscopy surveillance strategies. Lancet Gastroenterol Hepatol. 2026 Aug;11(8):720-726. doi: 10.1016/S2468-1253(26)00128-7. Epub 2026 Jun 19. PubMed 42320508 ↗
  • Ebert MP, Reichermeier S, Klug L, Lynen Jansen P, Pox C. Clinical Practice Guideline: Colorectal Cancer-Diagnosis, Treatment, Prevention, and Long-Term Follow-Up Care. Dtsch Arztebl Int. 2025 Dec 26;122(26):729-734. doi: 10.3238/arztebl.m2025.0196. Epub 2025 Dec 26. PubMed 41195479 ↗
  • Laven-Law G, Symonds EL, Simpson K, Coats M, De Silva M, Hollington P, Cock C, Wassie MM. Risk of Advanced Colorectal Neoplasia at Follow-up Colonoscopy After Synchronous Adenoma and Clinically Significant Serrated Polyp. Clin Gastroenterol Hepatol. 2026 Feb;24(2):544-553. doi: 10.1016/j.cgh.2025.07.023. Epub 2025 Aug 5. PubMed 40774589 ↗

Individual participant data

Plan to share: No

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Jul 2026; primary completion for Dec 2026, 5 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 3, 2026
First posted
Jul 16, 2026
StartEst.
Jul 1, 2026
Primary completionEst.
Dec 31, 2026
CompletionEst.
Dec 31, 2026
Last update
Jul 16, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 16, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07708415
Lead sponsor
Gansu Provincial Hospital
Responsible party
Xu Zhang (M.D Endoscopic diagnosis and treatment center, Gansu provincial hospital, Lanzhou, Gansu, China, Gansu Provincial Hospital) — Principal investigator
First posted
Jul 16, 2026
Start date
Jul 1, 2026 (estimated)
Primary completion
Dec 31, 2026 (estimated)
Completion
Dec 31, 2026 (estimated)
Last update
Jul 16, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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