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Enrolling by invitationNCT07701746Updated Sep 2, 2026

Ultrasound Guidance vs Landmark Technique for Internal Jugular Vein Catheterization

An observational study in Central Vein Catheter and Ultrasound, sponsored by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital. Enrolling by invitation at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-02.

Sponsored by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
144
Ages
18 Years to 75 Years
Sex
All
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Study summary

Central venous catheterization (CVC) is a fundamental procedure in anesthesiology and reanimation practice for critical clinical processes such as hemodynamic monitoring, vasoactive drug infusion, and fluid resuscitation. The internal jugular vein (IJV) is frequently preferred due to its superficial anatomical location and ease of access. This study aims to observe and compare the ultrasound (USG) guidance and the landmark method in patients scheduled for IJV catheterization.

Read the detailed description

Traditionally, IJV catheterization applied with a blind technique based on anatomical landmarks is increasingly being replaced by USG-guided applications. However, the landmark method is still actively and widely used in the field due to equipment limitations or practical habits. A total of 144 patients aged 18-75 who are operated on in the general operating room unit and have a central venous catheter inserted will be included in this prospective study. Patients will be divided into two groups: those receiving USG-guided catheterization (n=72) and those receiving the landmark technique (n=72). All patients will receive standard general anesthesia after an 8-hour fasting period. The physician performing the cannulation with USG will have at least 2 years of USG experience and/or a certificate.

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Conditions studied

  • Central Vein Catheter
  • Ultrasound
03

In context

Lead sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital is the lead sponsor of 59 studies on the registry; 25 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study population consists of patients aged 18 to 75 years who are scheduled to undergo surgery in the general operating room unit at Dicle University Faculty of Medicine Hospital and require the insertion of a central venous catheter. All included patients will receive standard general anesthesia following an 8-hour fasting period

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients aged 18-75 years
  • Patients operated on in the general operating room unit
  • Patients undergoing central venous catheter insertion

Exclusion criteria

Exclusion Criteria:

  • Refusal to participate in the study
  • Patients aged under 18 or over 75 years
  • Patients undergoing emergency surgery
  • Presence of coagulopathy
  • History of infection, operation, or cannulation in the intervention area
  • Allergy to USG gel
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
144 participants (estimated)
Patient registry
No

Groups and cohorts

  • Ultrasound guided central venous catheterisation

    Patients (n=72) receiving internal jugular vein catheterization performed with ultrasound guidance by an anesthesiologist with at least 3 years of USG experience or certification.

    Procedure: Ultrasound Guidance

  • Landmark technique

    Patients (n=72) receiving internal jugular vein catheterization performed using the traditional blind/anatomical landmark technique (typically by residents or clinicians gaining experience).

    Procedure: Landmark Technique

Interventions

  • ProcedureUltrasound Guidance

    Patients (n=72) receiving internal jugular vein catheterization performed with ultrasound guidance by an anesthesiologist with at least 2 years of USG experience or certification.

  • ProcedureLandmark Technique

    Patients receiving internal jugular vein catheterization performed using the traditional blind/anatomical landmark technique (typically by residents or clinicians gaining experience).

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What researchers measure

Primary outcomes

  1. Number of Needle Redirections.

    Time frame: Intraoperative.

Secondary outcomes

  1. First-Attempt Success Rate

    Time frame: Intraoperative

  2. Total Access Time

    Time frame: Intraoperative, up to 15 minutes

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Study locations

1 site
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References and documents

Publications

  • Sazdov D, Srceva MJ, Todorova ZN. Comparative Analysis of Ultrasound Guided Central Venous Catheterization Compared to Blind Catheterization. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017 Sep 1;38(2):107-114. doi: 10.1515/prilozi-2017-0028. PubMed 28991766 ↗

Individual participant data

Plan to share: No

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jul 2026 (actual). Primary completion is estimated for Sep 2026, 2 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 8, 2026
First posted
Jul 14, 2026
StartActual
Jul 1, 2026
Primary completionEst.
Sep 15, 2026
CompletionEst.
Sep 30, 2026
Last update
Sep 2, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 2, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07701746
Lead sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Responsible party
Fikret Salık (Medicine Doctor Associate Professor in Anesthesiology, Dicle University) — Principal investigator
First posted
Jul 14, 2026
Start date
Jul 1, 2026
Primary completion
Sep 15, 2026 (estimated)
Completion
Sep 30, 2026 (estimated)
Last update
Sep 2, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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