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Enrolling by invitationNCT07701720Updated Sep 2, 2026

Ultrasound Guidance vs. Landmark Technique for Catheter Malposition in IJV Catheterization

An observational study in Catheter Malposition and Central Venous Catheterization, sponsored by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital. Enrolling by invitation at 1 site in Turkey (Türkiye). Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-09-02.

Sponsored by Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
204
Ages
18 Years to 75 Years
Sex
All
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Study summary

Central venous catheterization (CVC) via the internal jugular vein (IJV) is a fundamental procedure in anesthesia and intensive care for hemodynamic monitoring, fluid resuscitation, and vasoactive drug administration. While modern clinical guidelines strongly advocate for ultrasound (USG) guidance, the traditional anatomical landmark technique remains widely utilized due to equipment availability or clinician habits. Proper positioning of the catheter tip is critical to prevent severe long-term complications; however, comparative data regarding catheter tip malposition between these two routine techniques-especially when confirmed by postprocedural bedside chest X-ray-require further prospective evaluation. Objective:

The primary objective of this prospective observational study is to compare ultrasound-guided versus landmark techniques for internal jugular vein catheterization with respect to catheter tip malposition, as determined by postprocedural bedside chest X-ray. Secondary objectives include the evaluation of the number of needle redirections, first-attempt success rate, total procedure time, and the incidence of mechanical complications (such as accidental arterial puncture or hematoma formation)

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Conditions studied

  • Catheter Malposition
  • Central Venous Catheterization
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In context

Lead sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital is the lead sponsor of 59 studies on the registry; 25 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Adult and elderly patients (18-75 years) undergoing elective or scheduled surgery in the general operating room unit of Dicle University Faculty of Medicine Hospital who require central venous catheterization via the internal jugular vein as part of routine perioperative care. The catheterization technique (ultrasound-guided or landmark) reflects the routine practice of the performing physician; no technique is assigned by the study for research purposes.

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Inclusion criteria

  • Patients aged 18-75 undergoing surgery requiring central venous (internal jugular) catheterization

Exclusion criteria

Exclusion Criteria:

  • Refusal to participate
  • age \<18 or >75
  • emergency surgery
  • coagulopathy
  • infection, prior surgery, or prior cannulation at the insertion site
  • allergy to ultrasound gel
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Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
204 participants (estimated)
Target follow-up
2 Days
Patient registry
Yes

Groups and cohorts

  • Ultrasound-guided group

    IJV catheterization performed under real-time ultrasound guidance

    Procedure: Ultrasound-Guided Technique

  • Landmark technique group

    IJV catheterization performed via anatomical landmark technique

    Procedure: Landmark Technique

Interventions

  • ProcedureUltrasound-Guided Technique

    Internal jugular vein catheterization performed with real-time ultrasound visualization of the vein to guide needle insertion.

  • ProcedureLandmark Technique

    Internal jugular vein catheterization performed using external anatomical landmarks without real-time ultrasound guidance.

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What researchers measure

Primary outcomes

  1. Incidence of catheter tip malposition

    Time frame: Assessed on postoperative bedside chest X-ray, immediately following the procedure

Secondary outcomes

  1. Incidence of Procedural Mechanical Complications

    The occurrence and rate of immediate mechanical complications directly related to the intervention, specifically tracking accidental carotid arterial punctures and hematoma formations.

    Time frame: During the procedure and up to 24 hours post-operatively.

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Study locations

1 site
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References and documents

Publications

  • Riaz A, Shan Khan RA, Salim F. Ultrasound guided internal jugular venous cannulation: comparison with land-mark technique. J Coll Physicians Surg Pak. 2015 May;25(5):315-9. PubMed 26008653 ↗

Individual participant data

Plan to share: No

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Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Started Jul 2026 (actual). Primary completion is estimated for Oct 2026, 3 months after the start.

How these figures are worked out, and which studies are left out of them.

Registered
Jul 8, 2026
First posted
Jul 14, 2026
StartActual
Jul 15, 2026
Primary completionEst.
Oct 15, 2026
CompletionEst.
Oct 15, 2026
Last update
Sep 2, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 2, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07701720
Lead sponsor
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Responsible party
Fikret Salık (Medicine Doctor Associate Professor in Anesthesiology, Dicle University) — Principal investigator
First posted
Jul 14, 2026
Start date
Jul 15, 2026
Primary completion
Oct 15, 2026 (estimated)
Completion
Oct 15, 2026 (estimated)
Last update
Sep 2, 2026

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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