An interventional study of questionnaire application in Vaccine Hesitancy, sponsored by Iuliu Hatieganu University of Medicine and Pharmacy. Not yet recruiting. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-29.
Sponsored by Iuliu Hatieganu University of Medicine and Pharmacy · Not applicable, Interventional, and Other
Purpose: To identify and evaluate the factors that influence parents' attitudes towards vaccination.
Objectives:
Method Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III. Collection of clinical data by applying questionnaires completed voluntarily by parents
Parents' knowledge and attitudes towards vaccinating their children
Introduction Vaccines administered in childhood save 2-3 million lives globally each year. They have contributed substantially to the decline in infant morbidity and mortality rates over time and represent the most cost-effective method of reducing childhood illness.
A high vaccination rate among the population protects both those who have received the vaccine and those who have not, through the phenomenon of herd immunity. Maintaining protection plays an important role in the development of the paediatric population. Early childhood infections can affect the growth and development of children, impacting the health and cognitive abilities of future adults. Although vaccines reduce morbidity and mortality, many parents do not vaccinate their children. In developing countries, the main causes of non-vaccination are low socio-economic status, poor parental education and limited access to medical services. On the other hand, in more developed countries, parents, despite having easy access to vaccines and information, choose not to vaccinate their children.
In order to increase vaccination rates, it is necessary to understand where parents' beliefs come from. Parents' refusal to vaccinate their children has been associated with: the costs involved in the vaccination process, fear of adverse effects, both immediate and long-term, the belief that vaccines are ineffective, and various attitudes. These include: lack of trust in the state authorities responsible for implementing vaccination programmes, religious conflicts, and the idea of over stimulating the child's immune system with "too many vaccines".
Recently, a decisive factor has emerged that influences parents' opinions: social media. Studies conducted to date have shown the impact of anti-vaccine content posted online on the decline in vaccination rates.
Hypothesis: The decline in vaccination rates among the paediatric population is occurring in both developed countries and low socio-economic environments, with parental attitudes being the main decisive factor.
Purpose: To identify and evaluate the factors that influence parents' attitudes towards vaccination.
Objectives:
Research area: research into parents' attitudes and knowledge about vaccines and their interaction with healthcare professionals.
Study type: descriptive, cross-sectional, representative sample study. Target population: parents of children under 18 years of age evaluated at the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III, between January- Sept 2026.
Representative sample data collection
Materials and methods:
Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III. Collection of clinical data by applying questionnaires completed voluntarily by parents. By completing the informed consent form, parents gave their consent to participate in this study.
Clinical data to be recorded: gender, age, place of residence, level of education, profession, age of children, vaccination status of parents and children. Collection of data on: parents' knowledge and attitudes towards vaccines, the doctor-parent relationship and parents' level of trust in doctors, and knowledge about infections. Distribution of questionnaires to family doctors and paediatricians to assess the communication relationship between doctors and parents in the context of vaccines.
Descriptive statistics: Data will be stored in accordance with legal provisions for the protection of patients' identity and personal data. Statistical analysis of the data will be performed using Microsoft Excel and SPSS.
The results and conclusions will be disseminated through the publication of articles in scientific journals.
121 studies on the registry are indexed under Vaccination Hesitancy; 14 are open to participants now.
This study's planned enrollment of 200 is below the median of 516 across 98 interventional studies indexed under Vaccination Hesitancy.
Browse Vaccination Hesitancy studies →Iuliu Hatieganu University of Medicine and Pharmacy is the lead sponsor of 56 studies on the registry; 15 are open to participants now.
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- parents of patients under 18 years of age admitted to the Emergency Children's Hospital, Cluj-Napoca, Paediatrics Clinic III during January -sept 2026
Exclusion Criteria:
- parent of patients under 18 years who refuse to participate or to fill in the questionnaire and the consent form
Distribution of questionnaires to parents of patients under 18 years of age admitted in the Emergency Children's Hospital, Cluj-Napoca
Other: questionnaire application
questionnaire application
The questionnaire administered to parents and caregivers, entitled "Parents' Knowledge and Attitudes Toward Childhood Vaccination", was designed to identify the factors influencing vaccine acceptance, hesitancy, and refusal.
The questionnaire items were structured into the following main domains: Sociodemographic characteristics Vaccination status Attitudes and motivations Sources of information and trust Data obtained from the questionnaires will be analysed. The distribution of quantitative variables will be assessed using the Shapiro-Wilk test. Categorical variables will be expressed as absolute frequencies and percentages. Associations between categorical variables were evaluated using the Chi-square test. Comparisons of non-parametric quantitative variables between two independent groups were performed using the Mann-Whitney U test.
Time frame: bseline
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Jul 2026; primary completion for Jul 2026, 0 months later.
Of 82 non-industry interventional studies with no phase under Vaccination Hesitancy, half reached primary completion within 6 months of starting (the median), counting those still running; a quarter within 3 and three quarters within 14. This study's planned 0 months is below that.
Counting every sponsor, half of 83 studies reached it within 5 months; a quarter within 2 and three quarters within 14.
How these figures are worked out, and which studies are left out of them.
This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Iuliu Hatieganu University of Medicine and Pharmacy