ClinicalTrials.gg
Not yet recruitingNCT07662915Updated Jun 23, 2026

NCMT Technique and Jodhpur Technique and Excimer Laser in Treatment of Non Vitiligo Leucoderma

An interventional study of Melanocyte Keratinocyte Transplantation Procedure (MKTP) and Jodhpur Technique in Leukoderma, sponsored by Al-Azhar University. Not yet recruiting. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2026-06-23.

Sponsored by Al-Azhar University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jul 2026, 4 months ago, but the record still lists the study as not yet recruiting.
Phase
Not applicable
Study type
Interventional
Enrollment
22
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

This study aims to compare the efficacy and safety of Melanocyte Keratinocyte Transplantation Procedure (MKTP) combined with 308-nm excimer laser versus Jodhpur technique combined with 308-nm excimer laser in the treatment of stable non-vitiligo leukoderma. Twenty-two patients with stable depigmented lesions will be enrolled. In each patient, two comparable lesions will be treated using different techniques. Clinical outcomes including percentage of repigmentation, color match, time to onset of repigmentation, complications, and histological changes will be assessed during follow-up to determine the optimal surgical treatment approach for non-vitiligo leukoderma.

02

Conditions studied

  • Leukoderma

Browse trials for

03

In context

Vitiligo

343 studies on the registry are indexed under Vitiligo; 96 are open to participants now.

This study's planned enrollment of 22 is below the median of 36 across 265 interventional studies indexed under Vitiligo.

Browse Vitiligo studies →

Lead sponsor

Al-Azhar University is the lead sponsor of 531 studies on the registry; 172 are open to participants now.

Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age 18 to 60 years.
  • Clinically diagnosed stable non-vitiligo leukoderma.
  • Stable lesion(s) for at least 6 months with no progression.
  • Inadequate response to conventional medical therapy.
  • Presence of two comparable lesions
  • Willingness to participate and provide written .

Exclusion criteria

Exclusion Criteria:

  • Vitiligo or suspected active vitiligo.
  • History of keloid or hypertrophic scar formation.
  • Active infection at donor or recipient sites.
  • Bleeding disorders or anticoagulant therapy that cannot be safely discontinued.
  • Pregnancy or lactation.
  • or uncontrolled systemic disease.
  • Inability to comply with follow-up visits.
  • Unrealistic expectations regarding treatment outcome.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Immunosuppression

A weakened immune system. It can come from an illness, such as HIV or some blood cancers, or from medicines that turn the immune system down, for example after an organ transplant or for an autoimmune disease; steroids at higher doses count.

Read whether the line is about a condition or about medicines, and which medicines and doses it means.

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
22 participants (estimated)

Study arms

  • Experimental
    MKTP+ excimer laser

    Melanocyte Keratinocyte Transplantation Procedure followed by 308-nm excimer laser therapy

    Procedure: Melanocyte Keratinocyte Transplantation Procedure (MKTP) · Device: 308-nm Excimer Laser

  • Experimental
    Jodhpur Technique + Excimer Laser

    Jodhpur technique followed by 308-nm excimer laser therapy

    Procedure: Jodhpur Technique · Device: 308-nm Excimer Laser

Interventions

  • ProcedureMelanocyte Keratinocyte Transplantation Procedure (MKTP)

    Autologous melanocyte-keratinocyte cell suspension prepared using enzymatic separation and applied to a dermabraded recipient site.

  • ProcedureJodhpur Technique

    Autologous non-cultured epidermal cell transfer technique using dermabraded donor skin particles applied directly to the recipient site without enzymatic processing

  • Device308-nm Excimer Laser

    Excimer laser therapy initiated approximately 14 days after surgery, administered twice weekly for 12-16 weeks with dose adjustment according to erythema response

06

What researchers measure

Primary outcomes

  1. Mean Percentage Repigmentation of Target Lesions

    Time frame: 6 months

Secondary outcomes

  1. Time to Onset of Repigmentation

    Time frame: Up to 6 months

  2. Color Match Assessment

    Time frame: 6 months

07

Study locations

No study locations are listed for this record.

08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Jul 2026; primary completion for Jul 2026, 0 months later.

Of 63 non-industry interventional studies with no phase under Vitiligo, half reached primary completion within 19 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 33. This study's planned 0 months is below that.

Counting every sponsor, half of 67 studies reached it within 17 months; a quarter within 8 and three quarters within 32.

How these figures are worked out, and which studies are left out of them.

Registered
Jun 17, 2026
First posted
Jun 23, 2026
StartEst.
Jul 1, 2026
Primary completionEst.
Jul 1, 2026
CompletionEst.
Sep 1, 2027
Last update
Jun 23, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 23, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07662915
Responsible party
Mohamed Mahmoud Mohamed Mahmoud (MD researcher, Al-Azhar University) — Principal investigator
First posted
Jun 23, 2026
Start date
Jul 1, 2026 (estimated)
Primary completion
Jul 1, 2026 (estimated)
Completion
Sep 1, 2027 (estimated)
Last update
Jun 23, 2026

Study contacts

Mohamed Mahmoud
Contact
mas912m@gmail.com
+201091865997

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion